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Proteomics
The goal of structural genomics is the determination of the structures of all proteins encoded inthe genome of an organism. NMR is one of the essential techniques used for protein structure solution.
MALDI-TOF mass spectrometry has found a wide acceptance for industrial, large-scale SNP Genotyping and synthesis/quality control of oligonucleotides. For these applications, Bruker Daltonics’ MALDI-TOF solutions offer a unique combination of data accuracy, speed, automation capability, and cost-effectiveness.
Protein Structure Determination (X-ray)
X-ray powder diffraction (XRPD), single-crystal diffraction of biological and chemical crystals are of varying importance for the different steps of the pharmaceutical value chain, from drug discovery through drug development and production.
Structural biology is one of the most important applications of NMR in Life Sciences today and can be optimally performed with the AVANCE series and its purpose-designed user interfaces.
MALDI- and ESI-MS/MS are the core technologies for protein identification and in-depth characterization in expression proteomics. Adjusted automation suites are essential for successful sample tracking, archiving and retrieval for low to high throughput approaches.
Bruker Optics now offers new accessories designed for the analysis of proteins and DNA/RNA with infrared spectroscopy.
Mass spectrometry continues to contribute its ability as a superior tool for protein expression profiling and analysis of biomarker patterns from bodily fluids and tissues. These scientific applications are addressing areas such as predictive medicine, toxicology and in the very near future, diagnostics.







