For more than 25 years, Bruker has been the leader in MALDI mass spectrometry innovation. MALDI is amenable for any analytical task and this is exemplified in the scientific literature where MALDI imaging publications dominate 5:1 over the next ionization technology. Bruker delivers MALDI imaging systems that incorporate novel MALDI technologies to accomplish any targeted or untargeted imaging study.
Images are generated by collecting MALDI data in a virtual grid pattern applied to a sample surface. Thin sections of samples are mounted onto conductive glass slides and a layer of MALDI matrix is applied by aerosol. Bruker’s MALDI imaging technologies allow the user to define the measurement area and resolution directly using a digital image of the sample. The size of the virtual grid establishes the image resolution and is tailored for the experimental question to be answered.
Given each MALDI spectrum is acquired from a discrete virtual grid without oversampling, the resulting dataset is a molecular signature of the unique area sampled. Unlike ionization systems which utilize oversampling, Bruker’s MALDI imaging technologies produce ion images which do not exhibit image ‘blurring’.