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工艺开发与反应监测

API的工艺开发包括对用于生产所需原料药的配方的初步设计以及工艺放大。

利用布鲁克MATRIX-MF近红外光谱仪对小规模化学批反应进行实时监测,可以为未来的生产工艺带来巨大效益。不必等待实验室分析和对反应的更严格控制,有利于更早地检测到关键问题,并帮助选择正确的标准,确定一条安全的可扩展路径。

NMR is highly complementary to vibrational spectroscopy in the field of reaction monitoring. It’s quantitative by nature, structurally rich and non-intrusive making the technique extremely useful to identify and characterize reaction intermediates, gain insights into the reaction mechanisms and determine kinetics.

[Bitte nach "Chinese (Simplified)" übersetzen:] NMR complements IR in the lab, enhancing process understanding and consequently the robustness and confidence of IR in situ process monitoring in the plants. InsightMR enables monitoring of chemical reaction by NMR in real-time under real conditions. With integrated data acquisition and analysis, and a custom designed flow tube, InsightMR is the perfect solution to complement your vibrational spectroscopy measurements.

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