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Advanced Polymer Analysis with MALDI-TOF MS

 Did you know...

... that MALDI-TOF MS offers direct molecular weight distributions and more?

In contrast to GPC, MALDI-TOF MS yields absolute molecular weights not relative ones. MALDI-TOF MS is a fast and versatile method to address challenges in the synthesis or quality control of polymers. Structural features such as repeating units (monomer), sum mass of the end-groups, average masses Mn and Mw are readily available. MS/MS analysis using MALDI-TOF/TOF instrumentation yields information about the block length of di-block-copolymers and masses of single end-groups.

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... that MALDI-TOF MS allows for polymer analysis in minutes?

The simplicity of the measurement and the straightforward data analysis using dedicated software like PolyTools™ or Polymerix (Sierra Analytics) enables the user to get structural information in a few minutes.

... that TLC MALDI is a fast method for silent change analysis?

These days supply chains of raw material change quickly often accompanied with loss of information (silent change) which increases the need for a more thorough quality control of incoming goods. The inexpensive combination of thin layer chromatography (TLC) and MALDI-TOF MS is a valuable solution for this challenge.

Scils workflow polymer

... that TLC MALDI not only allows for lipid analysis?

Industrial materials such as additives are often difficult to analyze using HPLC MS. Employing TLC MALDI is an alternative approach to reveal impurities or map changes against a standard.

Application note

 

 

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