All of our MALDI-TOF mass spectrometers can analyze ions over a wide m/z range, enabling analysis of a broad spectrum of molecules, from smaller molecules, for example lipids and peptides, up to polymers and intact proteins larger than 100 kDa. With our PAN panoramic focusing, peak resolution is maintained, and the new 10 bit digitizer of the autoflex maX enhances dynamic range for a more complete view of low abundance sample components. In MALDI MS imaging applications, this expansion of dynamic range can be invaluable for complex samples such as tissue, but also beneficial for all applications, including QC workflows, direct TLC-MALDI, and polymer characterization.
Characterization of poly n-butylacrylates on the autoflex maX system.
MALDI-TOF spectrum of the poly n-butylacrylate synthesized in bulk at 100°C* illustrates the dynamic range of the autoflex maX system with signal intensities the range of three orders of magnitude. Both very low intense signals around 35 kDa and fine spectral detail in the low mass range (~3kDa) are clearly detected without saturation.
*Agirre, J. I. Santos, A. Etxeberria, V. Sauerland, J. R. Leiza, Polym. Chem., 2013, 4 (6), 2062 – 2079