SmartProbe.jpg
11B-NMR spectra
2D COSY

硼 NMR

硼是一种无机及有机化合物中的常见元素。

[Bitte nach "Chinese (Simplified)" übersetzen:] Boron is a common element used in inorganic and organic compounds. The spectra of decaborane show 11B-NMR spectra with and without proton decoupling. The 2D COSY was recorded in just a few minutes.

Back
Structure Verification and Elucidation

结构验证和解析

15检测实验和结构工程

[Bitte nach "Chinese (Simplified)" übersetzen:] 15N detection experiments and structural work

Structure verification and determination require high quality spectra, which are characterized by excellent lineshape for all nuclei and high sensitivity for all experiments. Well balanced rf channels and matched B1 homogeneity of all coils are a prerequisite, if best sensitivity is to be obtained for any type of application. Excellent solvent suppression enables applications in water, like biomolecular experiments and metabonomic studies.

Back
19F, 1H HMBC Experiment
19F, 1H HOESY and HMBC experiment

氟 NMR

氟是一种在许多药物类化合物中都存在的元素。

[Bitte nach "Chinese (Simplified)" übersetzen:] Fluorine is an element found in many pharmaceutical compounds. Essential structural parameters are accessible with heteronuclear NOE experiments, like the HOESY experiment. Fluorine is also used as a spy for studies of the metabolism of active agents, and for enzymatic HTS screening.

(Top) 19F, 1H HMBC Experiment of cytostaticum fluorurazil. The correlation shows a spatial neighbourhood to the proton of the heterocycle.

(Bottom) Comparison of the 19F, 1H HOESY and HMBC experiment. While the HOESY spectrum has a correlation to the proton of the heterocycle, the HMBC shows a correlation to the NH protons.

Back
更多信息