Reactive oxygen and nitrogen species are involved in a vast range of major diseases including cardiovascular disease, Alzheimer’s disease, Parkinson’s disease, cancer, multiple sclerosis, autism, and infections. These free radicals have an unpaired electron, creating a highly reactive molecule that will try to obtain an additional electron from wherever it can. In the cells and tissues of the human body this can result in major damage to lipids, proteins and DNA, ultimately affecting the function of cells, tissues and organs.
Some of the most abundant radicals produced in natural biochemical reactions are reactive oxygen species (ROS) such as hydroxyl, hydroperoxyl and superoxide radicals, and reactive nitrogen species (RNS), such as nitrogen monoxide and peroxynitrite.
In this webinar, Kalina Ranguelova, Applications Scientist for Bruker BioSpin, will outline how Bruker electron paramagnetic resonance (EPR) technology can be applied to the detection of ROS and RNS, focusing in particular on the use of spin trapping techniques.v
The webinar will highlight how Bruker’s EMXnano spectrometer, with its compact desktop footprint and easy-to-use functionality, makes this technology accessible to more labs and researchers than ever before.