Pharma Knowledge Seminar

Revealing Molecular Mysteries through NMR Spectroscopy

In collaboration with CSIR-IICT Hyderabad and Bruker Biospin

Seminar Overview:

Unlocking the Secrets of Peptides, Oligos, Biosimilars, Drug Conjugates and their Impurities with NMR

Are you curious about the fascinating world of molecular investigation?

Let’s break it down!

We’re diving into the magic of Nuclear Magnetic Resonance (NMR), specifically tailored for the Pharma/BioPharma industry.

Date: Thursday, Friday, June 20th and 21st, 2024

Time: 9:00 AM - 5:00 PM

Venue:
CSIR- Indian Institute of Chemical technology
Uppal Main Road, Tarnaka, Hyderabad,
Telangana 500007. INDIA
Swami Vivekananda Auditorium

Presentations: 9:00 AM until 02:00 PM
followed by live practical sessions

Please mark your calendar and plan to attend!

What Awaits You:

NMR Sessions and Live Demos: Experience the live demonstrations of NMR instruments! It’s like playing with a high-tech detective kit for molecules!

Small Molecular & Peptidic Drugs: Many drug candidates are small organic molecules with diverse atomic arrangements to address different therapeutic requirements. Similarly, certain peptides are also used as drugs. Based on the sequence of the amino acids, the proteins adopt specific three-dimensional shape and thereby determine biological functions. At the seminar, we’ll unravel the ways to determine the 3D solution-state structures of small organic molecular drugs and peptides/proteins.

Biosimilars: Biologics and biosimilars are like the superheroes of medicine - they fight diseases! But they’re complex. NMR steps in as our superhero sidekick, helping us fingerprint comparison of their structures with natural therapeutic analogs. 

Impurity Identification and Quantification of Pharmaceutical Products: Ever wondered how we detect those sneaky impurities in medications? NMR reveals their hidden identities. We’ll explore how NMR ensures the purity and safety of pharmaceuticals.

Drug Conjugates: Brace yourself for mind-expanding talks by experts from IICT Hyderabad and Bruker Biospin. They’ll unravel the mysteries of drug conjugates - those clever combinations that enhance drug effectiveness.

Tips and Tricks Live Session: Ready to roll up your sleeves? We’ll guide you through experimental setups for 1D, 2D, HSQC, DOSY, and more. It’s like being in a molecular lab, conducting experiments that could change the future of medicine.

Learn from the Experts: Our seasoned instructors - true NMR wizards - will guide you through real-world applications and case studies. They’ll show you how NMR advances peptide and Biosimilar/biologics research. It’s like having Yoda teach you the ways of the NMR Force.

Network and Collaborate: Share experiences, discuss challenges, and explore potential collaborations.

Secure your spot now as seats are limited and embark on this exciting journey!

Pharma Knowledge Seminar: Agenda

Day 1: June 20, 2024

Time Duration Topics Presenters
08:00 AM - 09:15 AM 45 Min Registration and Networking  
09:15 AM - 09:25 AM 10 Min Welcome and Introduction Mr. Jayant Nagavkar & Dr. Jagadeesh Bharatam
09:30 AM - 10:15 AM 45 Min Advancements in NMR Techniques for Peptide Structure Determination Dr. Jagadeesh Bharatam, CSIR -IICT
10:15 AM - 11:00 AM 45 Min Overview of NMR Applications in Pharma/BioPharma Mr. Kathrine Holub, Bruker BioSpin
  15 Min Tea / Coffee Break
11:15 AM - 11:45 AM 30 Min Biosimilars and Similarity Studies Dr. Sharada Rao Patil, Syensqo Pvt. Ltd.
11:45 AM - 12:15 PM 30 Min Solid-state NMR Analysis of Pharmaceuticals Dr. T.G. Ajithkumar, NCL Pune
12:15 PM - 12:45 PM 30 Min Peptide Conformations and Impurity Indentification by NMR Dr. Rajesh Sonti, NIPER Hyderabad
12:45 PM - 01:15 PM 30 Min Small Peptide - Experiment and Analysis Dr. N. Chandrasekhar, Bruker BioSpin
01:15 PM - 01:45 PM 30 Min Fast Measurement - NMR Supersequences for Small Molecule Analysis Dr. Maksim Mayzel (Online), Bruker BioSpin
  45 Min Lunch Break
    Live Demo of Exciting Experiments  
02:30 PM - 04:30 PM 120 Min Experimental Set-ups for 1D, 2D, HSQC, DOSY

Dr. Chandrasekhar,

Dr. Jithender Reddy,

Dr. A.V.S. Sarma

NOAH Experiments
DOSY Experiments and Data Processing
Fast Measurement - NMR Supersequences for Small Molecule Analysis
  15 Min Tea / Coffee Break
04:45 PM onwards   NMR Lab Tour  
Roundtable Discussion - Challenges and Opportunities  

Day 2: June 21, 2024

Time Duration Topics Presenters
09:30 AM - 10:15 AM 45 Min Exploring the Role of NMR in Peptide, Oligo, and Biologics Analysis Dr. Victor Beaumont, Bruker BioSpin
10:15 AM - 11:00 AM 45 Min NMR Applications in Biosimilar Development Dr. Jithender Reddy G, CSR - IICT
  15 Min Tea / Coffee Break
11:15 AM - 11:45 AM 30 Min Zooming Inside HOS of In-Formula State Biopharmaceuticals by NMR Spectroscopy Dr. Ashutosh Kumar, IIT Mumbai
11:45 AM - 12:15 PM 30 Min Evolving Analytical Landscape Bio-NMR Analysis - Orthogonal Analytical Studies Dr. Ravi Krovidi, PAA Pvt. Ltd.
12:15 PM - 12:45 PM 30 Min BioHOS: Advanced Spectral Analysis and Quantification of Biologic Modifications Dr. Christian Fischer (Online), Bruker BioSpin
12:45 PM - 01:15 PM 30 Min Mestrelab Software Solutions Mr. Sandeep Baluni, Mestrelab
01:15 PM - 01:45 PM 30 Min Bruker Products / Benchtop NMR Solutions for Small Molecules and Biotherapeutics Analysis Dr. Devendra Babu, Bruker BioSpin
    Lunchbreak
    Live Demo of Exciting Experiments  
02:30 PM - 04:30 PM 120 Min Peptide Sample Measurements in Formulation State - Its Challenges and Solutions

Dr. Chandrasekhar,

Dr. JithenderReddy,

Dr. A.V.S. Sarma,

Mr. Sandeep Baluni

HOS Experiments Set-up and Processing for Similarity Studies
Utilizing NMR Software Tools for Pharmaceutical Analysis
Fourier 80 MHz - Live Show
GxP Solutions - Mdrive Software Live Show
  15 Min Tea / Coffee Break
04:45 PM onwards   Roundtable Discussion - Challenges and Opportunities  

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