Conferences & Tradeshows

Well Characterized Biologics & Biological Assays

October 25-28, 2021, Virtual

At this conference

Well Characterized Biologicals & Biological Assays is the industry’s most trusted and longest running event providing the regulatory guidance and analytical characterization and biological assay strategies to ensure accurate CMC submissions.


For more than 60 years, Bruker has enabled scientists to make breakthrough discoveries and develop new applications that improve the quality of human life. Bruker’s high-performance analytical and diagnostic systems explore life and materials at molecular, cellular and microscopic levels in the applied, molecular, and pharmaceutical research areas. Please join us at our virtual booth and during our Tech Spotlight Presentation events.

When: Monday, 25 October 2021

Time: 11:35 AM - 12:05 PM Eastern Time

Track: Well Characterized Biologics

Title: Comparative assessment of mAb higher order structure in biopharmaceutical development using novel NMR and chemometric analysis

Developments in pulse sequences and instrumentation along with the incorporation of chemometric tools permit NMR spectroscopy to report comparative metrics for higher order structure analysis (HOS) of intact monoclonal antibodies (mAbs). These 1D and 2D NMR chemometric methods can be used in different applications, including forced degradation HOS studies on mAbs, given the high sensitivity and resolution of the technique.

Presented By: Victor Beaumont, Senior Scientist, Pfizer

Victor Beaumont

Senior Scientist, Pfizer

Victor received his Bachelor’s Degree in 2013 at the University at Buffalo, NY under the advisement of Dr. Thomas Szyperski, where he worked on pulse sequence validation for large biomolecules. He then joined Dr. Patrick Loria’s group at Yale University to work on his PhD thesis regarding the functional implications of protein motions using NMR. Victor has been at Pfizer since 2019 as an NMR specialist for biotherapeutic characterization. During his time there, Victor has worked to develop chemometric methods for structure comparability of monoclonal antibodies through different applications.