ViscoDirect Software Module
Enhanced Analysis of Viscoelastic Behavior
The ViscoDirect Software Module for Bruker’s NanoWizard BioAFM platform enables the automated, AI-assisted, viscoelastic analysis of living cells, tissues, and soft matter, significantly improving the speed and ease of atomic force microscopy (AFM) experiments.
Biological samples and soft matter exhibit both elastic (solid-like) and viscous (fluid-like) behavior that determines how they sense and respond to mechanical forces. During AFM measurements, viscoelastic matter exhibits distinct loading and unloading profiles. Bruker’s ViscoDirect module enables fast, automated measurement of a sample’s elastic modulus and fluidity (viscosity), while accounting for sample thickness and force indentation.
Using supervised machine learning, this proprietary* fitting module extracts viscoelastic parameters from force-distance curves (FDC) during the AFM measurement, simplifying applications, such as mechanical gradient mapping, multiscale characterization of cellular structures, and quantification of the time-dependent behavior and viscoelastic response of hydrogels, polymers, and colloidal materials.
Only ViscoDirect delivers:
- Immediate viscoelastic analysis and online results during the AFM measurement
- Automated, AI-assisted FDC analysis
- Viscoelastic parameters from new and existing data
*Developed in collaboration with the group of Prof. R. Garcia and licensed from the Spanish National Research Council (CSIC).
Accessories to extend your BioAFM capabilities
Bruker offers an extensive range of BioAFM system add-ons, accessories, and modes to deliver maximum experimental and sample control, superior versatility, and enhanced useability. These options extend the range of applications and experiments supported by Bruker BioAFMs far beyond what is possible with any other BioAFM system on the market today.
Available options include optical systems/accessories, electrochemistry solutions, electrical sample characterization, environmental control options, software modules, temperature control, acoustic and vibration isolation solutions, and more.
Download our accessories handbook to learn more.
