Approaching Ettlingen on the motorway A5 from Frankfurt/Stuttgart (from the North/East) or from Basel/Strasbourg (from the South) leave the motorway at exit no. 48 Karlsruhe Süd (Rheinstetten, Ettlingen) and follow the right lane in direction to Rheinstetten. You will pass the "Radisson" Hotel and on your left hand side. After the industrial area "Beim Runden Plom" turn in direction to Ettlingen. At the next traffic lights drive straight on. After about 500 meters, you will see the Bruker Biospin building on your left hand side. After the left-hand bend, turn left and you will reach Bruker Optics building after about 150 meters.