Imaging VIP Day

Poster hall Pharma/Biopharma

The ever increasing need to accelerate time to market for new drugs places a burden on analytical labs in terms of sample volume and confidence in data required for decision making. Innovations in trapped ion mobility mass spectrometry and software give BioPharma scientist new tools to characterize biologic drugs with more speed and keep up with the pace of development. Mass spectrometry imaging is becoming an essential tool to understand diseases and determine drugs PK and metabolism which are essential to address the right tissue and evaluate toxicity early.

Bottom-up protein characterization

Poster: Routine Analysis of Host Cell Proteins in Antibody Preparations using PASEF

Poster: Application of PASEF MS/MS scans to monoclonal antibody peptide mapping

Poster: A unified workflow for automatic mapping of disulfide bonds in protein therapeutics based on high resolution LC-QTOF

Intact protein characterization

Poster: Characterization of a Fusion Protein Dimer by a UHR ESI - QTOF Mass Spectrometer

Mass Spec Imaging 

Poster: MALDI Imaging Mass Spectrometry for the study of cardiovascular pathology

Poster: Distinct deposition of amyloid-bspecies in brains with Alzheimer’s disease pathology visualized with MALDI imaging mass spectrometry

Poster: Hepatic Lipid Analysis in an Experimental Model of Chronic Alcohol Exposure using of MALDI-TOF and MALDI-FT-ICR Mass Spectrometry

MALDI based protein characterization

Poster: Rapid Identity Assays for mAb Development, Production Control and Release

 

 

ASMS 2019

Poster: Simultaneous Profile and Determination of Statin Composition in Various Media and Biological Matrices by Accurate Mass and High Resolution LC-QTOF-MS

Poster: CHO Cell Culture Media Profiling and Unknown Identification by Liquid Chromatography and Accurate Mass High Resolution Mass Spectrometry

Poster: Structural study of a PEGylated therapeutic protein by MALDI-ISD and ESI-QTOF

Poster: Streamlining mAb characterization with a PASEF based disulfide analysis workflow

Poster: Separation of Asp/IsoAsp Isobaric Peptides using Trapped Ion Mobility Spectrometry (TIMS)

Poster: The benefit of peptide CCS value prediction and experimental determination

Poster: A software platform for peptide synthesis quality control by both LC-free MALDI-TOF and LC-ESI-QTOF molecular weight determination

Poster: A software platform for the quality control of synthetic oligonucleotides

Poster: Optimized data analysis pipeline for MALDI imaging based tumor typing from FFPE tissue samples evaluated on six benchmark classification tasks

Poster: Predicting Lymph Node Metastasis in Endometrial Cancer by multi-modal mass spectrometry imaging

Poster: Mass Spectrometric In-Depth Proteome Analysis of the Kidneys from Rat Model of Diabetic Nephropathy

Poster: Metabolomics Characterization of Cell Culture Media by Ultrahigh Resolution LC-QTOF-MS Analysis

Poster: Analysis of Histones from HEK293 Cells using a QTOF with Trapped Ion Mobility and PASEF Workflows

Poster: Identification and Quantitation of Phosphopeptide Positional Isomers using Trapped Ion Mobility Spectrometry and PASEF