How microCT can provide insight into dynamic disease processes
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Overview
In this webinar, Prof. Greetje Vande Velde will give an overview of her work, which involves lung and brain infections. Dr Vande Velde will describe how high-field MRI and low dose µCT complement each other; where micro-CT gives high contrast in the lungs and MRI allows clear visualization of the brain.
The webinar will also introduce the use of the Skyscan 1278 micro-CT from Bruker, that was used in Dr Vande Velde’s experiments, as is a non-invasive imaging technique that can be used with the same animal multiple times - to not only create high quality images, but to also minimize the number of animals used in the trials.
What to expect
This webinar will look at how non-invasive imaging can yield much better results at the pre-clinical stage and how the ethics of (pre-) clinical research can also be improved. Expect to see how the Skyscan 1278 MicroCT in combination with a BioSpec 9.4 T MRI can be used to improve the data generated from animals, regardless of the species or disease type. Viewers should also expect to see the many benefits this technique offers, as well as the types of disease that it is useful for.
Key Topics
Introduction to Micro CT
- Data Processing (better and more relevant data)
- Higher Image Quality
- Ability to Image an animal multiple times
- High spatial & temporal resolution
- Low radiation dosage
- Improved pre-clinical workflow
Combining CT with MRI
Applications:
- Lung disease
- Cardiac disease
- Metabolic diseases
- Cancerous tumors
- Brain imaging
- Animal disease model phenotyping
Improving Ethics:
- Reducing the number of (transgenic) animals used in pre-clinical research/studies
- Non-invasive
Who should attend
The webinar is primarily aimed at those who work with animals, in particular transgenic animals, and are looking to refine and reduce, or improve their workflow. Additionally, people who are involved in lung, cardiac and neuroscience research would find this webinar useful.
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