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Toxtyper 2.0 complete application solutions

From comprehensive screening to targeted libraries and semi-quantification

Example data demonstrating simultaneous, highly sensitive detection of drugs in human urine. Following simple sample preparation (liquid-liquid-extraction) of 1 mL of urine, the Toxtyper 2.0 permits detection down to 0.8 ng/ml.

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Open library concept

The appearance of new drugs, such as synthetic cannabinoids, makes it necessary to update the screening methods quickly. Toxtyper 2.0 provides ready-to-use spectral reference libraries, constantly updated through contributions from our customers and collaboration partners. User-defined library entries can be created in a few mouse clicks, allowing laboratories to quickly respond to new patterns of illicit and licit drug misuse.

Interactivity provides easy access to high-value data

The intuitive and highly dynamic Toxtyper 2.0 graphical user interface can be customized to the users' preference. For easy and fast result evaluation identified compounds can be sorted by various parameters, e.g. by peak intensity, retention time or alphabetically. In addition color coding of deviating parameters in retention time or mass shift, or of lower purity scores, supports the evaluation options.

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Screening, confirmation, and semi-quantitation in one run

The standard workflows can be extended by additional automated methods for semi-quantitation using any of the Toxtyper 2.0 libraries. A one-point calibration for the target compounds using internal standards provides data regarding the concentration range (e.g. above or below a target value) within the same single LC-MSn analysis.

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