timsTOF Pro

timsTOF Pro - Re-defining proteomics throughput and sensitivity

Speed and sensitivity translating into high proteome coverage

The combined power of trapped ion mobility spectrometry (TIMS) and Parallel Accumulation Serial Fragmentation (PASEF) allows for greater proteome or sub-proteome (e.g. Phosphoproteome) coverage without requiring the large sample amounts (typically 1-4µg of a peptide mixture on column) often used in proteomics.

Superior results can be obtained from less than 200ng sample load, therefore reducing both sample preparation costs and MS maintenance frequency. Using a 90 min gradient length more than 5,400 protein groups can be identified from a typical human cell line lysate. The timsTOF Pro can also deliver reproducible quantitative information from smaller amounts of highly complex mixtures.

Deep proteome coverage with short gradients
Deep proteome coverage with short gradients (30 min, 60 min and 90 min) using 100 ng of HeLa digest

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