SpatialOMx on the timsTOF fleX rapidly provides a high definition, label-free overview that merges chemical information with vital morphological context. Whether it’s proteomics, lipidomics, glycomics, or metabolomics, the timsTOF fleX is the ideal dual-source platform for MALDI guided SpatialOMx analyses. First, use the patented smartbeam™ 3D technology to conduct fast, label-free MALDI Imaging for mapping the distribution of molecules in your sample that identify molecularly unique regions of interest for microextraction and deeper X-Omic analyses. Then, apply timsTOF flex’s powerful LC-MS/MS with PASEF for the highest level of identifications and for greatest confidence in your results. Regions of interest may be selected manually or use SCiLS Lab automated segmentation to know exactly where your microextraction will have the highest impact.
Bruker Daltonics IntelliSlides now support a brand new workflow which allows for fast, simple, and highly automated set-up of Imaging acquisitions using flexImaging 6.0 and COMPASS for flex 2.1.
Using the TissueScout to scan barcoded IntelliSlides allows for fast recognition of the correct sample image in flexImaging as well as alignment of the sample with instrument optics. The new workflow includes checks to confirm instrument performance, and automatic assignment of measurement regions using dedicated algorithms for whole tissue sections and Tissue microarrays (TMAs).
MALDI Imaging is made simple with Bruker Daltonics.
Additional information about the efficiency improvements with IntelliSlides and flexImaging 6.0 can be found in the video: