- Unique 4-axis concept
- 3D imaging of both large life specimens and clared tissue
- Compact, vibration-free and robust design
- Resolution down to 280 nm in 3D
- Browser-based user interface
The MuVi SPIM is a horizontal setup designed to image large volumes very fast. The unique 4-axis concept with its two-sided illumination allows four combinations of illumination and detection.
This provides four orthogonal views of the specimen without the need for sample rotation, avoiding shadowing effects and facilitating long-term imaging. Combined with the sample mounting from below, this allows maximized acquisition speed and high precision of data fusion while preserving stability and integrity of the sample.
The MuVi SPIM capacities can be further extended to enable imaging of optically cleared samples and performing photomanipulation experiments (e.g. ablation, bleaching). For this purpose, the MuVi SPIM CS (Cleared Sample) and the MuVi SPIM PM (Photomanipulation) have been conceived.
Typical applications of the microscope include in toto imaging of animal models such as Zebrafish embryos, Drosophila larvae, marine biology samples, plant and root development, large cleared tissue samples. Adding the photomanipulation unit provides further flexibility, enabling optical interaction with the samples.