CaptiveSpray nanoBooster for LC/MS

Ease of Use

CaptiveSpray provides a vortex gas that sweeps around the emitter spray tip to desolvate and focus the Taylor cone into the MS inlet capillary. The vacuum seal to the MS ion guide draws all of the sample ions into the MS increasing the efficiency of sample transfer from the spray tip into the mass spectrometer. The direct connection to the inlet capillary eliminates the need for any source adjustment making the CaptiveSpray source truly Plug-and-Play.

Smart Ionization Support by Dopant-enriched Gas Supply

The nanoBooster option allows the modification and vapor enrichment of gas that flows around the emitter. Dependent on the used dopant, either charge stripping or charge enhancement of peptides and proteins can be achieved during the ionization process. Charge enhancement is advantageous for the analysis of large biomolecules due to the reduction of the mass-to-charge (m/z) ratio. Furthermore, higher charge stages increase efficiency of electron transfer dissociation (ETD) MS/MS.