Efficient identification methods for laboratory testing, active surveillance and screening of patients are therefore in high need to avoid spreading of CRKP. The MBT Subtyping Module looks automatically for a blaKPC related peak in the sample spectrum after successful identification of the Enterobacteriaceae listed below. If present, the MALDI Biotyper will report this sample as a presumptive blaKPC positive.
The MBT Subtyping Module quickly detects blaKPC expressing Enterobacteriaceae. Please note that negative results do not indicate that these strains are susceptible, but will require additional confirmation methods.
An automated check for presumptive presence of KPC is done after successful identification of the following species:
- Citrobacter freundii
- Enterobacter aerogenes
- Enterobacter asburiae
- Enterobacter cloacae
- Enterobacter kobei
- Enterobacter ludwigii
- Escherichia coli
- Klebsiella aerogenes
- Klebsiella oxytoca
- Klebsiella pneumoniae
- Klebsiella variicola
- Serratia marcescens
The MBT Subtyping Module detects also cfiA positive Bacteroides fragilis strains and PSM-mec carrying Staphylococcus aureus strains.
K. pneumoniae with blaKPC related peak (blue line)
ESBL K. pneumoniae negative control (dotted red line).