Single Crystal Diffraction

SC-XRD Application Note

SC-XRD, Application Note

Single-crystal X-ray diffraction, commonly referred to as X-ray crystallography, is an analytical technique in which X-ray methods are employed to determine with certainty the actual arrangement of atoms within a crystalline specimen. The science of X-ray crystallography originated in 1912 with the discovery by Laue that crystals diffract X-rays. Since that time, single-crystal X-ray diffraction has developed into the most powerful method known for obtaining the atomic arrangement in the solid state.


X-ray crystallographic structure determination can be applied to a wide range of sizes of structures, from very small molecules and simple salts, to complex minerals, synthetically prepared inorganic and organometallic complexes, natural products and biological macromolecules, such as proteins and even viruses.