In situ, multimodal, nanoscale imaging is highly desired for today’s multidisciplinary research, e.g. energy, material and biological studies. Bruker recently developed batch-fabricated, robust nanoelectrode probes that have an exposed, active Pt tip apex of ~250 nm height and an end tip radius of ~25 nm. These probes are used in PeakForce Scanning Electrochemical Microscopy (PeakForce SECM) for simultaneous capture of topography, conductivity, and quantitative nanomechanical information at the nanoscale, and electrochemical properties at sub-100 nm resolution. Bruker also developed Force Volume SECM providing improved electrochemical kinetic quantification, 3-D nano-electrochemical and nanomechanical mapping. The nanoelectrode probe - by design - also enables nanoelectrical measurements in liquid, in particular PeakForce-TUNA, PeakForce-KPFM and PFM. In this talk, Dr. Huang will introduce these unique techniques with a variety of applications examples related to today’s highly multidisciplinary research.