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Recent Webinars


SCiLS Lab: Feature Extraction with Principal Components

Mass spectrometry imaging produces highly complex data that is difficult to access and understand. This webinar demonstrates feature extraction with principal components and advanced visualization techniques in SCiLS Lab

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Scientists' Choice Awards Winner

Label-Free High-Throughput MALDI TOF Mass Spectrometry in Drug Discovery

Speaker: Matthias Trost, Professor of Proteomics, Newcastle University

The presentation will give a current overview of label-free high-throughput MALDI TOF mass spectrometry and its use in drug discovery screening. It will explain the basics of MALDI TOF mass spectrometry and the benefits of label-free screening compared to current labeled approaches. Data presented will focus on enzymes in the ubiquitin system (deubiquitylases, E2/E3 ligases) and protein kinases.

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TargetScreener HR

Eliminating False Positives and Negatives: Correctly Report Results the First Time

Speaker: Dr. Carsten Baesmann, Director of Applied Markets Solutions Development, Bruker Daltonics

The webinar provides a detailed overview of how high-resolution mass spectrometry and data acquisition using a 'catch all compound' acquisition scan mode can reduce instances of reporting false positives and negatives.

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Webinar Toxicology

Toxtyper Screening - A New Kind of Forensic Evidence

Speaker: Dr. Andrea Steuer, Forensic Toxicologist Dept. of Forensic Pharmacology & Toxicology, Institute of Forensic Medicine, Zürich

The webinar briefly introduces the field of forensic toxicology and focus on the use of the Toxtyper system for urine screening within this field.

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Webinar Archive


28.06.2016 Structure Elucidation with Trapped Ion Mobility Spectrometry

Presenters: Dr. Christian Bleiholder, Ph.D., Assistant Professor of Chemistry & Biochemistry, Florida State University

Ion mobility spectrometry - mass spectrometry (IMS-MS) offers great potential to structurally characterize biological macromolecules and their complexes, ranging from amyloid assemblies to viral capsids and allosteric control of protein function. Trapped ion mobility spectrometry (TIMS) is a novel ion mobility method with unique capabilities for structural studies. One unique feature of TIMS is the ability to trap ions for extended periods of time. Further, TIMS has demonstrated unparalleled ion mobility separation power. This webinar will discuss the technical and theoretical foundation of TIMS, demonstrate the capabilities of TIMS in terms of its resolving power and ability to trap ions for extended periods of time, and illustrate its potential for structural biology studies in conjunction with novel computational methods.

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28.06.2016 Streamlining Drug Development Native LC-MS for Rapid Screening and Drug Product QC Release Testing of ADCs

Presenters: Dr. Lieza Danan-Leon, Senior Scientist, Head of Mass Spectrometry, Stemcentrx

In this webinar, Lieza Danan-Leon presents an LC-MS-based workflow performed in native conditions that can unambiguously provide drug load distribution and DAR values of ADCs at different stages in the drug development process. The Bruker maXis II UHR QTOF coupled to a non-denaturing HPLC separation was used to optimize the conjugation process in drug discovery and compare drug substance batches.

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01.04.2016 MALDI

Presenters: Toshiji Kudo, Ph.D. MALDI Application, Bruker Daltonics K.K.

MALDI-TOF MSはイオン化法にマトリックス支援レーザー脱離イオン化(Matrix Assisted Laser Desorption/Ionization、MALDI)、分析計に飛行時間型(Time Of Flight、TOF)を採用したタイプの質量分析装置であり、広範なサンプルに対応できることや測定時間の短さ、優れたメンテナンス性から様々な分野で広く用いられています。
Duration: 9 minutes
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日付 タイトル
16.06. 2016

Uncovering Metabolic Pathways in Disease to Support Drug Discovery Using High Resolution MALDI Imaging Mass spectrometry
Speakers: Ellen Jones, Ph.D., MALDI Imaging Research Center, Genentech; Dr. Dennis Trede, Ph.D., Managing Director, SciLS Bremen
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16.06. 2016

Rapid and Sensitive Quantitation of Approximately 100 Synthetic Cannabinoids In Serum by UHPLC-Triple Quadrupole Mass Spectrometry
Speakers: Rafaela Martin, PhD, Applications Specialist, Bruker Daltonics
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24.05. 2016

High-throughput MALDI TOF mass spectrometry for drug discovery
Speakers: Dr Matthias Trost, MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee
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17.05. 2016

Biosynthetic Function of Genes in Plants and Their Consequences in Insects – a Metabolite Profiling Approach Driven by Automatic Compound Identification
Speakers: Sven Heiling, Ph. D., Department of Molecular Ecology, Max Planck Institute for Chemical Ecology
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13.04. 2016

Top, Down…Bottom, up… Middle what? What Does it All Mean? And Why is it Important for mAb Characterization?
Speaker: Jason S. Wood, PhD
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07.04. 2016

A comprehensive workflow for glycopeptide analysis
Speaker: Kristina Marx, Stuart Pengelley
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23.03. 2016

Meeting the challenges of metabolite identification in MS-based matabolomics
Speaker: Prof Dr Liang Li, University of Alberta
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04.11. 2015

New Developments in Quadrupole Time-of-Flight Instrumentation for Quantitative Proteomics
Speaker: Scarlet Beck, Florian Meier
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09.09. 2015

Advances in Glycopeptide Analysis
Speaker: Kathrin Stavenhagen, M.Sc.
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12.08. 2015

Development of Spectral Libraries, Predictive Software, and UHPLC-MS-SPE-NMR Technologies for Large-Scale Plant Metabolite Identification
Speaker: Lloyd W. Sumner, Ph.D.
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09.07. 2015

Application of High Resolution LC-QTOF Mass Spectrometry for Target and Non-Target screening of Emerging Environmental Contaminants in Surface and Waste Waters
Speaker: Nikolaos S. Thomaidis, Assoc. Prof.
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08.07. 2015

MALDI Imaging Moving Into The Fast Lane: Toward High Throughput Tissue Typing
Speaker: Dr. Ron M.A. Heeren
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Automated De Novo Identification and Profiling of Disulfide Bonds in Biotherapeutics Including Analysis of Disulfide Bond Scrambling in Monoclonal Antibodies
Speaker: Jason S. Wood, Ph.D.
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Accelerating Pharma R&D using Mass Spectrometry and NMR
Speaker: Dr. Meike Hamester, Dr. Matthias Trost, Dr. Jens Fuchser
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06.02. 2014

Identification of Microorganisms using MALDI-TOF
Speaker: Jennifer Reyes
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