Reaction monitoring is critical for process understanding, optimization and scaling up, leading to cost savings and ensuring the quality of the final product. It often provides insights into the chemical reaction mechanisms. Kinetic information can be extracted from time course data to build kinetic models that will be used to predict conditions, enabling effective process optimization, risk assessment and control.
The quantitative nature of electron paramagnetic resonance (EPR) and the non-intrusive nature makes the technique extremely powerful for the identification and characterization of radical reaction intermediates, providing insights into the reaction mechanisms and kinetics of chemical reactions.