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Molecular Imaging Using CEST MRI

A Free Preclinical Imaging Educational Webinar

Figure above:
MRI-CEST Imaging of the pH evolution of an acute kidney injury mouse model by means of Iopamidol, a pH-responsive contrast agent: a)T2w image Showing ROIs on kidney region; b) pH image before acute kidney injury onset; c) pH image at day 1 corresponding to an high level of damage; d) pH image after 3 weeks, corresponding to the recovery of the damage.

1 September, 2016

Seminar Overview

Due to its strengths like versatility, resolution and soft tissue contrast, magnetic resonance imaging (MRI) provides multiple advantages for Molecular Imaging applications. In particular Chemical Exchange Saturation Transfer (CEST) agents represent a prominent example of MR-based Molecular Imaging probes. One virtue of CEST agents is that their MRI contrast can be turned "on" by choosing the agent`s selective irradiation frequency. Importantly, this feature allows the visualization of different CEST agents in the same setting. The continual improvement of the agents and techniques in recent years makes CEST MRI a promising tool for Molecular Imaging research.

Key points

This webinar will focus on the latest advances of the CEST molecular imaging technique and state-of-the-art CEST imaging agents including:

  • LipoCEST agents providing an increased sensitivity and thus enabling a strong CEST contrast
  • CellCEST with the potential to visualize cells in vivo

(Click for Full Presentation Abstract)

Who should attend

The webinar addresses to all scientists and technicians working in the field of molecular imaging, preclinical imaging and small animal imaging and scientists who are interested in working with in MRI based Molecular Imaging in the future.


Presenter Molecular Imaging Using CEST MRI

Professor Silvio Aime

Professor of General and Inorganic Chemistry at the Department of Molecular Biotechnologies and Health Sciences
Head of the Center of Excellence on Molecular Imaging of the University of Torino, Italy (biography)

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