December 19, 2014

Announcement of Bruker HMDB Metabolite Library to Accelerate the Accurate Mass Identification of Target Compounds in Clinical Metabolomics

Dr. Liang Li

Dr. Liang Li from the University of Alberta

BILLERICA, Massachussetts - December 18, 2014: Bruker Daltonics today launches the newest member of its successful ‘omics’ knowledge generation platform, the Bruker HMDB Metabolite Library for its high-performance accurate mass QTOF mass spectrometry platforms.

Developed in collaboration with the University of Alberta, Canada, the Bruker HMDB Metabolite Library is a tandem mass spectrometry accurate-mass library designed to accelerate data analysis workflows in metabolomics research. It contains manually curated MS/MS spectra to speed the high-confidence identification of metabolites in human metabolomics and clinical research.  Compounds contained in the library were selected from the Human Metabolome Data Base (HMDB - www.hmdb.ca) and include metabolites found in urine, blood, other biofluids and cell extracts.


Dr. Liang Li,
Professor of Chemistry, at the University of Alberta, explained: “As a co-PI of the Human Metabolome Database (HMDB) project, my laboratory generated the original MS/MS spectral library of about 800 human metabolites using a low-resolution triple quadrupole mass spectrometer, which has been used by many in the metabolomics field for metabolite identification.  We are delighted to have collaborated with Bruker to produce a new Human Metabolite MS/MS accurate-mass library with much improved spectral quality.  This library, along with an automated spectral acquisition and processing strategy, allows researchers to identify metabolites very quickly and with highest confidence.”

Dr. Aiko Barsch, Metabolomics Director at Bruker Daltonics, commented: “The Bruker HMDB Metabolite Library delivers outstanding and robust performance in a very accessible platform.  We are excited to enhance the reach and capabilities of our ESI-QTOF mass spectrometers to make this innovative technology readily available and accessible - also for non-mass-spec-experts.”

Read more about Bruker HMDB Metabolite Library, here.

About Bruker Corporation (NASDAQ: BRKR)

Bruker Corporation is a leading provider of high-performance, scientific instruments and solutions for molecular, cellular and materials research, as well as diagnostics, industrial, clinical research and applied analysis. For more information, please visit www.bruker.com.

Media Contact:

Tony Lewtas Bruker Daltonics, Billerica, Massachusetts T: +1 978 663 3660 ext.1212 E: tony.lewtas@bruker.com