Software for Hyphenated Experiments

An open concept that can be used for many types of experiments

HyStar™ coordinates experiments when a liquid chromatography system is coupled with spectroscopic methods like NMR and/or MS. HyStar controls the chromatography system and the interfaces which divert the solvent flow into the spectrometers or intermediate collectors.

The HyStar concept is an open concept that can be used for many types of experiments. At a basic level it can be used to control the chromatography part of the standard LC-MS system in combination with NMR it can be used for a LC-SPE-NMR or an LC/MS-SPE-NMR system. Here HyStar triggers sample collection in solid phase extraction cartridges, based on chromatograms reconstructed from MS data. The sample is then transferred into a flow NMR probe and the measurement of the NMR spectra initiated. Alternatively, the transfer into NMR tubes in a SamplePro Tube is also possible.

Systems controlled by HyStar

In an setup for NMR spectroscopy the following instruments are compatible

  • Agilent (most 1100/1200/1260/1290 series instruments)
  • Waters (AQUITY™ UPLC)
  • Bruker/Spark Prospekt2 LC-SPE-NMR interface

    MS and NMR spectrometers:

    • Bruker Avance NMR spectrometers
    • Bruker Daltonics ion Trap MS
    • Time-of-Flight mass spectrometers
    • SamplePro Tube for collection of SPE fractions into NMR tubes