Microbiology & Diagnostics

Microbial Identification

Unbiased and fast identification of microorganisms down to the species level

Identification of microorganisms

Significant advances in microbiology have been achieved thanks to continuous innovations in mass spectrometry (MS) over the past decade. Now the standard in microorganism identification, Matrix-Assisted Laser Desorption/Ionization Time-Of-Flight (MALDI-TOF) MS enables microbiology laboratories to reliably and rapidly identify microbes, in a cost-effective manner.

A revolution in microbiology

Microorganisms identification to the species level is a key task of microbiology. Traditionally has been achieved by carrying out labour-intensive and time-consuming biochemical assays. Though current sequencing technologies may provide very precise insights, they are still far too slow and expensive. Bruker has successfully introduced an innovative, molecular-based mass spectrometric identification method that enables faster and more efficient analysis than conventional assays or sequencing.

By using our experience and expertise as a worldwide leading provider of MALDI-TOF mass spectrometry, Bruker developed the MALDI Biotyper® - a revolutionary approach for the analysis of microorganisms. This "Open Microbiology Concept" includes interfacing, own library creation and can be easily integrated into any laboratory environment. Within just a few years, the MALDI Biotyper® has become the worldwide leading solution for clinical microbiology, as well as for water, pharmaceutical and food testing.

MALDI Biotyper® - Changing microbiology

The MALDI Biotyper® (MBT) is a microbial identification system based on MALDI-TOF mass spectrometry, allowing unbiased identification of microorganisms within a few minutes down to the species level. The MBT is an easy, rapid, robust, high-throughput, cost-effective and efficient identification technology, ideally suited to microbial laboratories.

Due to its broad applicability, speed of analysis and low sample processing costs, the MBT is ideally suited to the role of microorganism identification. MALDI-TOF MS determines the unique proteomic fingerprint of an organism, and matches characteristic patterns with an extensive reference library to determine the organism´s identity. Continuous expansion of the reference library ensures that a broad range of microorganisms can be identified easily.

Bruker´s state-of-the art MALDI Biotyper® solutions

The best technology from the experts in mass spectrometry. As the leader in MALDI-TOF technology it is of great importance to Bruker to design robust, compact high-performance platforms intended for extensive and routine use in the microbiology laboratory.
The MALDI Biotyper® is a modular system designed to be configured according to individual laboratory needs. Bruker offers laboratories the choice of the microbial MALDI-TOF mass spectrometer that best fits their needs. Continuous hardware development has led to the 4th generation of Bruker´s benchtop MALDI Biotyper® system.

  • The NEW MALDI Biotyper® sirius one GP or RUO System, with Bruker´s proprietary lifetime* smartbeam™ solid state laser technology at 200 Hz repetition rate and positive ion mode. System improvements, including the newest electronics and high-performance vacuum system, generate very fast target exchange.
  • The NEW MALDI Biotyper® sirius GP or RUO System, with the same improvements, smartbeam™ 200 Hz laser and positive as well as negative ion detection. The additional capability of analysis in negative ion mode broadens the research applications, such as the analysis of lipids.
* Lifetime meaning 7 years or 500 million shots, whichever comes first.

 

For General Purpose use [In the United States, Japan and Taiwan: For Research Use Only (RUO)].

Not for use in clinical diagnostic procedures. Please contact your local representative for availability in your country.