rapifleX Tissuetyper

Novel Ion Source Design for Robust Day-to-Day Operation

  • Extends uptime between cleaning by orders of magnitude.
  • Easy access to self-aligning ion lenses when cleaning is in fact needed. The whole lens pack can be rinsed with Ethanol.
rapifleX Tissuetyper
Workflow Ion Source

Leading Software for MALDI Tissue typing

flexImaging

allows to set up and analyze individual datasets.

 

  • Wizard driven user-friendly set up of new experiments
  • True 64-bit application allows efficient handling of megapixel datasets
  • Direct access to single mass spectra
  • Batch acquisition
  • Co-register and super-impose virtual microscopic slides at full resolution for detailed histological annotation
MALDI Imaging data overlaid with virtual microscopic slide in flexImaging
MALDI Imaging data overlaid with virtual microscopic slide in flexImaging.

SCiLS Lab

statistical analysis software for mining MALDI Tissuetyper data. It allows both the analysis of individual datasets and the comprehensive analysis of clinical and pre-clinical studies.

 

  • User interface to handle multiple datasets
  • Univariate analysis: Mean intensities, standard deviations, uncovering discriminative m/z-markers (ROC analysis), hypothesis tests and discovery of co-localized m/z values
  • Unsupervised multivariate analysis: Spatial segmentation of large datasets, component analysis for extraction of underlying trends
  • Supervised tissue typing: Calculation of classifiers based on training data and classification of new observations / samples
Analysis of a clinical dataset in SCiLS Lab
Analysis of a clinical dataset with 21 independent patient samples in SCiLS Lab.

SCiLS Lab 3D

With the unparalleled speed of the rapifleX, 3D MALDI Tissuetyper studies are within reach. The SCiLS Lab 3D option allows the reconstruction, visualization, and statistical analysis of 3D Imaging datasets.

3D volume reconstruction and spatial segmentation of a kidney sample in SCiLS Lab
3D volume reconstruction and spatial segmentation of a kidney sample in SCiLS Lab.
Related Information