QCI-F-CRP_Banner.jpg

Versatile Quadruple Resonance CryoProbe for fluorine applications and triple resonance bio-NMR

New, versatile proton / fluorine optimized quadruple resonance NMR ‘inverse’ probe

Applications

Triple resonance HCN, HFC, HFN 
Triple resonance HCN with 2H decoupling
Quadruple resonance HFCN

New, versatile proton / fluorine optimized quadruple resonance NMR ‘inverse’ probe, featuring four fully independent channels (plus lock channel) for 19F{1H} and 1H {19F} experiments, and also simultaneous decoupling on multiple nuclei such as 13C, 19F and 15N - all without changing probe.

The novel QCI HFCN quadruple resonance probe addresses bio-NMR as well as fluorine NMR screening (3-FABS, FAXS, …) applications. The newest member of the Bruker CryoProbe family is designed for highest sensitivity on the 3 most important nuclei: 1H, 19F and 13C. Having a comparable sensitivity to classical triple resonance CryoProbes (TCI) for 1H and 13C, it adds 19F detection and decoupling capability with the performance of a dedicated fluorine CryoProbe! Potential applications range from triple resonance including deuterium decoupling for double and triple labeled bio-NMR samples to 19F{1H} screening applications and small molecule structure elucidation / verification work. The probe is compatible with shaped tubes for optimum performance on lossy samples.

Several recent discoveries in RNA research make this probe a very timely introduction to the field of cutting edge NMR research. The cryogenically cooled preamplifier for deuterium guarantees highest sensitivity for the lock channel, resulting in excellent stability of the spectrometer. This also permits the use of as little as a few percent of deuterated solvents.  In addition the QCI CryoProbe™ is equipped  with cold preamplifiers for 1H  and 13C. The probe is compatible with shaped tubes for optimum performance on lossy samples.