TopSpin 4.5

Get the most out of your Bruker NMR instrument with TopSpin software for both routine and advanced NMR acquisition and analysis.

TopSpin 4

TopSpin 4 is Bruker's standard NMR software for spectrometer control (Avance Neo, Fourier 80). It can also be used as a stand-alone installation for NMR data processing and analysis.

Current Releases

Windows 11

Updated with fix for SKB-643

TopSpin 4.5.0 & CMC-assist 2.26
(2857 MB)

(Created: 2025-07-31)

TopSpin for AVANCE NEO, Avance Core, Fourier 80 and processing in general.

This link allows for the direct installation of a complete acquisition/processing version for Windows 11.

MD5 checksum: c72ee90b1a74950d8ef05d683a0ff10b

System is under maintenance, please check system state

AlmaLinux 9

TopSpin 4.5.0 & CMC-assist 2.26
(2951 MB)

(Created: 2025-01-30)

TopSpin for AVANCE NEO, Avance Core, Fourier 80 and processing in general.

This link allows for the direct installation of a complete acquisition/processing version for Linux.

MD5 checksum: 50607e969289cbdd504d7de7072219a1 

System is under maintenance, please check system state

MacOS (Processing)

TopSpin 4.5.0 Processing Only
(1212 MB)

(Created: 2025-01-30)

TopSpin for macOS
MD5 checksum: 1b10f6d10504ab3262cc2d02b87906c7  

Requirements: macOS 12 or later.

System is under maintenance, please check system state

ISO Download

The ISO images include TopSpin for all supported operating systems and all additional Bruker software such as DynamicCenter. For programs that are supported on the MAC, the MAC version is also included in this image.

TopSpin 4.5.0
(8177 MB)

(Created: 2025-07-31)
TopSpin for AVANCE NEO, Avance Core, Fourier 80 and processing in general.
MD5 checksum: eeb4fc10b8ea08a26082c8bff4f8fc25

System is under maintenance, please check system state

TopSpin License Processing for Academia

Access to Academia licenses is restricted to academic customers. By using this web page for license requests you confirm that you are employed by or studying at an academic- or governmental institution and that you use the software exclusively in this context. Your request and the license generation will be logged. If you do not agree with this, please do not continue.

In the next step a personal ticket code will be generated for you. With this ticket code you can activate the Academia license on a compatible computer of your choice and use the software:

Request Evaluation License
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Request Academia License
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System is under maintenance, please check system state

Compatibility/Requirements

Supported Spectrometer Hardware

Table: Which Spectrometer Hardware is supported by which TopSpin version.

Shaded combinations have reached the End Of Service (EOS) , check also https://www.bruker.com/en/services/product-end-of-life.html.

- Indicates that this combination was never supported

1 No TopSpin support for DMX if a 4-phase modulator is available. If in doubt send the file ‘hardware_list’ from your spectrometer configuration directory to nmr-support@bruker.com

Supported Operating Systems

Spectrometer Control Support

The spectrometer software was tested and validated on following operating systems.

Software versions are listed as the first and last supported version, or as the first supported version with a '+' appended if support is still active.

Table: Acquisition support for 64-bit operating systems.