Bremen, Germany, March 29, 2019 –Bruker announces that on Wednesday, March 27th, its ultra-high sensitivity, high-throughput 4D proteomics platform, the timsTOF Pro mass spectrometer received the prestigious technology award during the Proteomic Forum 2019/XIII. Annual Congress of the European Proteomics Association (EuPA) in Potsdam, Germany. The EuPA Technology Award is given to recognize a team with an outstanding contribution in private industry who played a key role in commercialization of a proteomics technology.
In his acceptance remarks Dr. Gary Kruppa, Vice President for Proteomics at Bruker Daltonics credited R&D groups led by Dr. Melvin Park, and Oliver Raether with the invention and development of the trapped ion mobility (TIMS) technology. The TIMS technology is the basis for the PASEF method which was invented and developed by the same teams in collaboration with the group of Prof. Matthias Mann at the Max Planck Institute for Biochemistry in Martinsried, Germany. Dr. Kruppa further commented, “Bruker’s entire team supporting development, marketing and other commercialization aspects of the timsTOF Pro is delighted to have its innovation recognized by the proteomics community.”
Shown in the picture receiving the award are (from left to right): Prof. Uwe Voelker, conference co-chair and head of the Department of Functional Genomics at the University of Greifswald; Dr. Pierre-Olivier Schmitt, market manager for proteomics at Bruker Daltonics; Dr. Gary Kruppa; Dr. Scarlet Koch, market manager for proteomics at Bruker Daltonics; Karl Mechtler, EuPA Executive Committee member of EuPA and Head of the Protein Chemistry Facility at the Research Institute of Molecular Pathology (IMP) in Vienna, Austria.
About the timsTOF PRO with PASEF
The proprietary timsTOF Pro system uses PASEF, enabled by Trapped Ion Mobility Spectrometry (TIMS) to provide industry-leading data acquisition speed for shotgun proteomics. The unique dual TIMS geometry of the timsTOF Pro, combined with the time focusing of the ion packets in the TIMS device, means that the speed advantage provided by PASEF comes along with simultaneous improvements in sensitivity and quantitation. All of these gains in speed, sensitivity and quantitation maintain the advantages of Bruker’s high-performance QTOF mass spectrometers, including high mass resolution (resolving power of 50,000 FWHM even at highest data acquisition rates) in MS and MS/MS mode, ppm accurate mass, and high isotopic fidelity (True Isotopic Pattern, or TIPTM). The robust timsTOF Pro with PASEF gives scientists the tools to dig deeper into the complex cellular machinery with the potential to discover low-level, biologically significant peptides or proteins, or validate them in translational proteomics research.
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