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Elute LC series - Ultimate precision for mass spectrometric applications

Developed for highest reproducibility in retention time and peak shape, the new Bruker Elute HPLC systems are available in a variety of configurations to match your individual analytical LC-MS requirements.

Elute LC series

The heart of the Bruker Elute series of ultra-high performance liquid chromatography systems (UHPLC) are binary linear driven pumps that deliver virtually pulse-free, reproducible flow rates with a unique accuracy that will generate total confidence in your results.
Tailored to your applications, we provide a variety of complete liquid chromatography systems ready to start fulfilling your mass spectrometric demands:

  • Built for any routine lab applications the Elute SP offers standard 700 bar performance at a market-leading price/performance ratio.
  • The Elute UHPLC delivers high-end, 1300 bar performance for ultrafast LC-MS/MS applications. 

If your lab needs to combine on-line extraction with powerful UHPLC applications the Elute OLE UHPLC system is the perfect solution. 

For any demanding front end sample preparation steps the Elute HT, paired with the new PAL3 high throughput autosampler, is the ideal choice.  

Delivering maximum uptime - built for the routine lab

All Elute systems are designed to minimize gradient delay volume providing you with the benefit of shortest run-to-run times, saving your time in daily routine. Furthermore, the Elute binary high pressure mixing pump comes with an active piston backwash extending the lifetime of the pistons seals and therefore increasing your productivity and reducing costs of ownership.

LC-MS system


If you need high sample throughput on the EVOQ LC-TQ System, or need high flexibility for your LC-MS research methods on a Bruker impact II or compact QTOF, a fast exchange of solvents and switching to different LC-MS methods is beneficial. Whatever the case, Elute systems are your ideal partner in the laboratory to ensure flexibility as they can be equipped with different options such as column switching and selecting up to six different eluents.

 

 

 

Compass software

Elute LC series - Providing full confidence proven by a reliable design

The new Bruker Elute LC systems are built on an innovative pump design that provides you with a virtually pulse free, precise, volumetric flow control which is independent of flow rates, solvent compressibility or composition.

All Bruker Elute LC systems are configured with two pairs of serial-coupled, individually controlled linear drive pump heads. This principle makes it easy to transfer your UHPLC methods from one system to another, whether you need to transfer the method to an adjacent laboratory or even to a laboratory in a different country: Elute systems ensure quick and easy method transfer based on their robust technology. The flow path in the Elute Systems is optimized by minimizing the gradient delay volume. As a result you are gaining high chromatographic resolution, very fast gradients and ultimate short cycle times thus increasing your sample throughput and reducing your costs. 

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Delivering maximum uptime

By adding an ancillary pump, all Elute LC systems incorporate a true self-priming and self-purging-facility through the built in pump. The automatic purge and mobile phase priming process takes only a few minutes and makes it simple to exchange mobile phases to avoid any leaks in manual operations. In addition, the possibility of using two different sets of mobile phases, and the option of column exchange (up to six) provides a huge flexibility for routine labs, allowing highest productivity e.g. for the analysis of different sample types for overnight LC-MS runs.

Built-in priming pump

Seamless software integration by Compass

The control of the Elute LC systems are embedded into Bruker´s leading Compass software framework enabling our users a straightforward and easy access to the LC hardware modules for fast method development. A simple set-up of methods for sample batches and sample tables is guaranteed through the highly intuitive graphical user interface of Compass. Direct visualization of your results via a “Quick Data Viewer” as well as in-depth analysis enables all levels of operators gaining an extra productivity in their daily work.

Elute UHPLC – Settings standards in Retention time stability

Exceeding the guidelines for Multiresidue Screening

Today’s guidelines defining retention time (RT) deviations for pesticide screening are setting demanding new levels for the respective LC-MS methods. The new EU SANTE guidelines 11945 I 2015, require retention time deviations to meet < 0.1 min. Based on its innovative pump design the Elute UHPLC performs easily below this RT threshold by providing typical RT deviations of 0.01 min.

Multitarget Screening
Pesticide Screening of > 500 pesticides in food matrix separated on an Intensity Solo C18 RP column on the Elute UHPLC coupled to an impact II QTOF Instrument.

Ultrafast quantitative LC-MS/MS methods

Fast confirmation and quantitation of urine alcohol metabolite markers are needed to ensure high productivity for the forensic lab. These methods are routinely established by LC-TQ MS/MS methods. The Elute UHPLC coupled to the EVOQ LC-TQ enables fast and reliable confirmation and quantitation of Ethylglucoronide (EtG) and Ethylsulfate (EtS) in urine matrix.

Ethyl-glucuronide-_EtG__Ethyl-sulfate-_Ets_-350px.jpg
A fast three minute method to quantify EtG and EtS in urine with the new Bruker Elute UHPLC coupled to the EVOQ Elite triple quadrupole system.

Sensitivity for quantitation in food matrices

The minimum required performance level (MRPL) for Chloramphenicol detection in food is 0.3 ppb (EU decision 2003/181/EC). The Elute UHPLC coupled to the EVOQ Elite LC-TQ delivers great sensitivity (LLOQ 0.02 ppb) and ultra-sharp peak widths typically in the range of 2 sec. These levels can be achieved even in challenging matrices such as eggs.

Chloramphenicol 350px
Shown is the chromatographic peak width at half maximum (2.1 – 2.4 seconds range) for Chloramphenicol in egg matrix.

On-line sample preparation

On-line liquid extraction (OLE) has major advantages compared to off-line solid phase extraction (SPE) such as: direct injection of 100% of the sample in a closed automated system and using smaller particle sizes, leads to sharper focused chromatographic peaks. The Elute OLE system combines the advantages of an UHPLC system with the process advantages of OLE improving the quality and reproducibility of your results. For demanding sample preparation tasks e.g. for water analysis or analysis of complex matrices such as urine, the pre-enrichment capability of the Elute OLE delivers an added high value benefit to your laboratory.

Pestidcides in water
Pesticides in water (600 μl vol.), Triazophos 0.5 - 1000 ppt extracted and separated by an Elute OLE
system coupled to an impact II QTOF instrument.

Service & Support Elute LC series

Bruker Daltonics services are performed by factory trained and certified engineers. DIN EN ISO 9001:2000 requirements are fulfilled

Available services include:

  • Help desk service for a faster access to our support team, to your service order follow up and for general information
  • Planned maintenance, according to your requirement
  • Telephone support from highly-skilled troubleshooting professionals, to isolate and resolve hard- and software probl
  • Web-based remote instrument service for service diagnosis and applications support
  • Customer on-site repair and maintenance service
  • Spare parts availability typically over night or within a few working days worldwide
  • Compliance services for installation qualification, operational qualification / performance verification
  • Site planning and relocation
  • Advise to improve labs efficiency (consumable, method development & how to run the complete solution)

For Research Use Only. Not for Use in Clinical Diagnostic Procedures.