Small-Angle X-ray Scattering (SAXS)

The Universe of Nanostructure Analysis

SAXS and GISAXS are powerful methods for investigating particles in the 1 nm to 0.1 µm range. From a large variety of materials, such as polymers and proteins in solution, liquid crystals, surface characteristics, powders, bulk samples, and thin films the tools not only provide information on nanoparticle sizes, shape and size distributions, but also on structural dynamics.

The ability to visualize structures being formed —strongly supported by our modern software—is the critical success factor in nanoscience and nanotechnology, particularly since visible light microscopy fails to provide information at this scale.

Small-Angle X-ray Scattering, SAXS, SC-XRD, XRD
Dimensions measured by Small-Angle X-ray Scattering

Bruker solutions for SAXS and GISAXS take advantage of the latest developments in detector technology and high-flux microfocus X-ray sources, fulfilling the needs for precision, speed and reliability. Researchers value the high-quality information on structure-function relationship as it is the key to more successful research.

Today, the most exciting advances in new industrial materials and processes are based on key technologies in the nanoscale-domain (10-9m). Pharmaceuticals, cosmetics, functional food, smart polymers, intelligent surface coatings, sensorics and diagnostics greatly benefit from the tremendous process in SAXS.

SAXS has recently gained momentum as a powerful technique for structural biologists. Biological SAXS is indeed a great tool—complimentary e.g. to Protein Crystallography (PX), NMR & MS—for elucidating the size, conformation, and flexibility of proteins in solution, under physiologically-relevant conditions.

Bruker systems provide a level of data quality that previously was not achievable without a synchrotron, making the Bruker in-house system more attractive than ever.

  • The NANOSTAR laboratory beam-line series can be tailored to the individual needs of varying users’ applications. It offers a wide range of powerful microfocus X-ray sources which include the IµS, the TXS and the recently introduced METALJET.
  • Our new N8 HORIZON is the ideal solution for the characterization of solid-state nanomaterials. It possesses a revolutionary vertical beam path with an impressively small footprint.
  • The compact MICROpix and MICROcaliX series features the renowned Kratky-design, with a particular focus on highest measurement speed, precision and user convenience. The MICROcaliX uniquely combines microcalorimetry and SAXS in a single instrument and is designed in particular for the characterization of temperature-sensitive materials, such as liquid crystals, fats, polymers, protein gels and pharmaceuticals.
  • Our dual port METALJET with D8 VENTURE and the NANOSTAR is the perfect tool for the ‘hybrid analytical approach’, a key success-factor in today’s studies on proteins, membranes or large bio-functional complexes: biological SAXS and PX data are used for high-resolution modeling. Our economical, powerful in-house solution delivers both in one system.


For more information please contact us.