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Webinar Overview
In this webinar, Dr. Iris Zhou covers a range of PET/MR applications entailing neurology, oncology, and liver fibrosis, as well as contrast agent development in both mice and rats, and proves, as she says, the applications are “limited only by imagination”.
Dr. Zhou demonstrates the strengths of PET and MR and the combination of both with applications performed on the BioSpec 4.7 T with PET insert. She describes multi-mouse 11C studies of dopamine release and microglia dysregulation with multi-rat imaging and discusses the practicalities of carrying out multi-rodent studies. She then illuminates work on gastric cancer, where results can be used to stratify patients for more efficient treatment, non-alcoholic steatoheptatitis for early detection of fibrosis, and renal impairment, where results show a compensation via liver excretion, before covering contrast agent development.
She also describes 86Y as surrogate for Gd3+ as they are bother similar in size and chemistry, and shows via co-injection of both in rat that Gd3+ concentration can be determined. She further discusses how her studies with 52-labeled Mn DPDP for dual PET and MR imaging allow identification of where Mn is going on the long term.
On Demand Session
Key Learnings
Multi-rodent Neuro Imaging
- Technicalities of multi-rodent imaging
- Dopamine release
- Microglia dysregulation
Abdominal Imaging
- Gastric cancer
- NASH, Non-alcoholic steatoheptatitis
- Renal impairment
Contrast Agent Development
- 86Y as surrogate for Gd3+
- 52-labeled Mn DPDP
Who should attend?
Researchers wishing to gain an overview of a wide range of developments within the PET/MR imaging field will find this webinar to be an excellent critique.
Speakers
Dr. Iris Zhou
Instructor - Radiology
Massachusetts General Hospital & Harvard University
