PEGS Europe 2025

• Meet us at Booth 328: We're looking forward to meeting you in front of our biosensors and Beacon^® solutions that will be on display at our booth. Take the chance to discuss with our experts how our solutions can help you in current and future projects.
• Exhibitor Tutorials: Attend our tutorial sessions hosted by Bruker's expert team to discover the latest on Bruker’s Biosensors and Beacon antibody screening solutions.
• Beacon^® Live Demo at LxBio Ab: Come see a live demo of a Beacon^® system and observe single B cell antibody discovery happen in real time at LxBio’s world-class services lab in Lisbon.

Biophysical characterization of antibodies against membrane proteins: from high-throughput screening to on-cell kinetics

Location: Engineering Antibodies and Beyond Track

As antibody formats grow more complex, precise biophysical characterization becomes essential. We present a workflow combining high-throughput SPR for epitope binning and interaction screening, switchSENSE^® for affinity vs. avidity and ternary complex detection, and single-cell Interaction Cytometry for real-time kinetics on living cells in native context. Together, these tools support informed antibody design and selection.

Speaker:

Function Beyond Binding: Discovering Internalizing Antibodies and Screening T Cell Engager Libraries

Location: Antibody-Based Therapies Track

Traditional antibody discovery focuses on identifying monoclonal antibody binders, while pushing functional characterization into later, more expensive screening. The Beacon^® optofluidic platform, including the newest accessible Beacon Discovery™ system, enable researchers to characterize antibodies for function first and expand beyond single B cell screening to address ever-evolving biologic modalities and MOAs. We will highlight several case studies, including internalizing anti-PD-L1 antibody discovery and T cell engager library screening for cytotoxicity. 

Speakers:

Live Single B Cell Antibody Discovery in Real Time

Location: Professor Gama Pinto Avenue 1649-003 Lisbon - Portugal

Join us for an off-site live demonstration of the Beacon^® system performing single B cell antibody discovery. Experience how LxBio Ab uses their Beacon^® to rapidly assess antigen specificity in under 30 minutes and meet experts from Bruker Cellular Analysis and LxBio to discuss how optofluidics changes the game. Transportation to and from PEGS Europe and lunch will be provided – please register soon to secure your spot as space is limited!

As you are certainly aware, special compliance regulations apply to public officials* and healthcare professionals** with regard to the event we are planning. If you accept our invitation, we will therefore assume that you will observe the compliance regulations that apply to you and that you have the necessary employer approval.

*Government Official means according the Bruker policies any of the following: any officer, employee or representative of a government (national, regional or local) entity, or any public agency, public authority, department or instrumentality thereof, regardless of their rank or title (e.g. a regulatory official or government inspector); any person working for or advising a government-owned or government-controlled enterprise (e.g. a professor at a government-owned university, or a purchaser at a government-owned hospital); any person working for or advising a national or international non-governmental organization (e.g. an employee of the Red Cross or The World Bank); any person performing a public function or providing a public service, even if that person works for a non-governmental institution (e.g. private security personnel working in public functions); any person hired to review or accept bids for a government agency; any person with the responsibility to allocate or expend government funds; any person in a public law function, civil servant, judge or military personnel; any person acting for a political party, including party officials, candidates or individuals holding a position in a political party office; members of royal families; or immediate family members of any of the persons listed above. An immediate family member is a grandparent, parent, spouse, significant other, child, or sibling.

**A Healthcare Professional (HCP) is in accordance with the Bruker policies any physician, dentist, nurse, pharmacist or other individual who may prescribe, administer, purchase, dispense, recommend, or supply medical products or treatments or pharmaceutical products. In many cases, Bruker interacts with HCPs who work for state-owned hospitals (e.g. as medical scientists). These individuals will be classified as both HCPs and Government Officials.