Biosensors for molecular interactions

Molecular interactions govern the function of biomolecules in health and disease. They can activate or inhibit specific intracellular signals, they can result in the formation of functional complexes, they can induce conformational changes, in short, they are the linchpin of biological processes. Characterizing molecular interactions can therefore help to better understand these processes, creating essential knowledge to increase or restore health.

Bruker’s portfolio of biosensors offers innovative technologies for the biophysical characterization of interactions, providing data such as affinity, kinetic rates, and thermodynamics. It includes three core technologies:

Surface plasmon resonance (SPR): our high-performance SPR platforms offer unmatched throughput and multiplexing capacity. 

switchSENSE: with its versatile measurement modes, switchSENSE enables the characterization of complex interactions like multispecific binders, conformational changes, enzymatic activity, and ternary complexes.

Single-cell Interaction Cytometry (scIC): scIC allows the measurement of real-time binding rates directly on living cells, retaining the native microenvironment of interactions.

Explore our technologies and learn how they are used in other labs in our DISCOVER MOLECULAR INTERACTIONS Webinar series and other webinars.

Do you have interesting data you would like to share with the community to increase the visibility of your work and discuss results? Reach out to events.biosensors@bruker.com to discuss speaking possibilities in our webinars.