GenoType EHEC
Reliable Shiga toxin detection for early Enterohemorrhagic Escherichia coli (EHEC) diagnostics
Approximately 1,000 cases of infection caused by enterohaemorrhagic E. coli (EHEC) occur every year in Germany.
EHEC are highly contagious. Generally, 10 to 100 pathogens are enough to trigger an infection and possibly serious complications, such as haemolytic-uraemic syndrome (HUS). Improved laboratory diagnostics are therefore indispensable for the early diagnosis of the disease, in order to allay the clinical course and to avoid outbreaks, especially in public facilities.
Microbiological detection of EHEC is difficult, since EHEC can not be phenotypically distinguished from apathogenic E. coli. The most important diagnostic criteria in EHEC laboratory diagnostics has to be the detection of shiga toxins. For the identification of shiga toxins the use of molecular methods is recommended.
With our test system GenoType EHEC, such a method is available for your reliable and rapid EHEC diagnostics. Starting from cultivated samples, the Shiga toxin genes, that are important for the reliable identification of an EHEC infection, are detected. The differentiation of EHEC from Shigella ssp. and EIEC is ensured with the detection of the Shigella-specific virulence factor ipaH.
Benefits
Accurate results: A reliable differentiation of E. coli and Shigella ssp. as well as the detection of the diagnostically significant Shiga toxin genes and the intimin gene eae provides an accurate report, ensuring an effective EHEC diagnosis.
Rapid result: Detection is performed using culture material within one working day and thus allows for the rapid detection of EHEC.
Cost-efficient: No cost-intensive instrumentation is required for the procedure; consequently, economic set-up is also possible for smaller laboratories.
Please contact your local representative for availability in your country.
Not for sale in the USA.
Legal Manufacturer is Hain Lifescience GmbH – A Bruker Company
