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NMR Software

TopSolids

Bruker created TopSolids which is a workflow software package. This Solid state NMR software has been designed to give easy access. Learn more today.

TopSolids™ is an intuitive, workflow-based software package for solid-state NMR that is especially designed to give an easy access into the delicate setup of probe hardware and difficult experiments dedicated to insoluble protein systems and solid samples, e.g. from pharmacy, catalysis, batteries or material science. 

Bruker’s second generation of this interactive user interface provides menu-based, automated setup and acquisition of the most advanced multinuclear multi-dimensional NMR experiments using a comprehensive library of protocols and an optimum of automated procedure.

TopSolids™ ensures robust, secure spectrometer and probe setup and guarantees unsurpassed spectral quality by combining optimized acquisition parameters with fine tuning on the actual research sample.

With TopSolids™ Bruker offers a high level of convenience to use one of the most important techniques for understanding the structure and dynamics of insoluble samples with least user interaction to overcome the necessity for extensive prior knowledge.

It is your key to unlock solid-state NMR - it has never been easier or faster!

Technical Details

General features

  • Intelligent handling of project and parameters
  • PDF parameter reporting, including information about multidimensional experiments
  • Parameter import from a previous TopSolids project
  • Guided preparation of hardware settings (probe selection, reading a shim file, etc.)
  • Safety checks to minimize risk of damage for probe and sample
  • Queuing of multidimensional experiments
  • Uniform workflow

NMR System Requirement

  • Acquisition software Topspin 4+ and 3.6+
  • Avance NEO or newer console
  • 4 mm or 3.2 mm solid-state NMR probe (whether SB/ WB, double/ triple resonance)
  • Recommended for protein applications: BCU cooling unit
  • use of a MAS3 unit is generally recommended

Features for probe setup/ maintenance

  • Probe setup within less than 30 minutes possible
  • Only two samples needed: KBr, adamantane
  • Automated determination of 1H and 13C hard pulses
  • Automated z shimming routine
  • Automated quality evaluation of magic angle adjustment and shimming
  • Automated spectral referencing
  • Useful for regular probe performance tests