Available with tools for spectra database creation, identification, and quantification of compounds in complex mixtures as well as tools for chemometrics, including multivariate statistics.
Well-proven for the qNMR and quality control of small molecule APIs and raw materials, AssureNMR can now efficiently and accurately evaluate complex mixtures such as biologics, biofluids, and cell culture media. Targeted fingerprinting enables identification and quantification of key metabolites of cell culture media to indicate when the material is out of specification required for optimal production. The identification of components is enhanced by access to large, public databases.
Marco Guerrini from Ronzoni Institute, an expert in the analysis of the biologic heparin, said: “AssureNMR increases the analysis speed and is customizable. It allows the skilled NMR user to automate their workflow and make their sophisticated method of NMR acquisition and analysis accessible to any NMR lab, even one without an expert in the field of glycosaminoglycans.”
Anthony Ribeiro, Ph.D., of Duke University Medical Center said: “These features represent major enhancements to the AssureNMR software package for the detailed analysis of biofluid systems.”
(1) L. Poppe et al., Anal. Chem. 2013, 85, 9623−9629; L. Poppe st al., Anal.Chem. 2015, 87, 5539-5524.
A Track Record of Reliability
AssureNMR can be used to provide a detailed summary of sample composition and classification of a wide variety of samples, all in complete automation.
Featuring full integration for instrument control, AssureNMR uses Assure-System Suitability Test to verify and optimize the instrument performance. With capacity for use within GMP environments, AssureNMR provides a traceable record of sample analysis and results, ideal for R&D and production environments that need documentation of performance qualification tests.
Choose Your Solution
With new capabilities and product levels, you can choose the one that best fits your screening needs:
Industrial Applications & Solutions
For use when:
Mixture and Pure Material Analysis
Spectral Database (SBASE)
NMR System Requirements