Banner webinar 21 july 2020

核磁共振波谱法测定新冠病毒RNA 成分的二级结构

Christian Richter from GU Frankfurt will discuss how he and his colleagues are part of the organization researching COVID19 with NMR.
This webinar took place on July 21st 2020

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总览

抗击新冠病毒引起的全球大流行病是当前社会和科学面临的最大挑战。德国法兰克福大学核磁共振研究小组发起倡议,于2020年3月底成立了一个由30个小组组成的国际联盟。利用核磁共振波谱,他们正在针对所有与新冠病毒相关的蛋白质进行结构检测,而其中的RNA成分则正在形成新型药物的潜在靶点。 

此外,他们将用RNA和蛋白质来筛选一个片段数据库,这个片段库是为了便于后续化学操作而设计的。(在本次研讨会中)我们专注于本项目的RNA部分,还将介绍项目的生化背景、核磁共振分配策略,并展示我们的筛选结果。 

Speakers

Dr. Anna Wacker
Dr. Anna Wacker
Anna Wacker works as a PostDoc in the Schwalbe Lab. Her main research focus lies on conserved RNA elements involved in regulatory pathways in prokaryotes. For Covid19-NMR, she uses her experience in RNA structural characterization by NMR spectroscopy to coordinate the workflow of RNA sample design, production, measurement, assignment and screening.
Dr. Christian Richter
Dr. Christian Richter
Christian Richter is an NMR expert who is jointly responsible for the supervision of the high-resolution NMR spectrometers at the institute. He has also developed new NMR experiments for the conformational determination of RNA. In addition, he has developed methods for side chain assignment in unfolded protein. C. Richter has also established fragment based screening experiments for RNA and proteins in the institute.