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solariX MRMS -明确的同位素精细结构质谱图

Solarix MRMS磁共振质谱仪系列, 提供7T、12T和15T磁场强度的选择。

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solariX系列仪器的主要特点

先进技术实现同位素精细测量(IFS)日常化

与其他FTMS技术相比,solarix结合了最新磁共振质谱、和谐阱分析池和磁场离子轨迹控制技术,这是实现超高的质量分辨率的先决条件,并获得宽质量范围同位素精细结构(IFS)常规测定的结果。

可靠的测量和判别分子式

IFS提供了其他类型质谱仪测定数据中丢失的额外信息。利用solariX XR和solariX 2XR 卓越的IFS检测能力,不仅可以获得待分析物的精确质量,还可以确定其元素组成。结合Bruker SmartFormula 算法,可以在最大置信度下给出明确的分子式。    

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eXtreme 解决方案揭示真实杂环原子含量

把MRMS的领先技术的应用到您的研究工作中

  • 7T solarix XR MALDI质谱仪具有独特的ESI/MALDI双离子源,是非标记小分子MALDI成像分析的最高标准。该系统可用于研究药物和代谢物在组织中分布,并将组学研究和空间位置关联
  • 使用7T solariX 2XR和流动注射分析的FIA-MRMS工作流程不需要连接耗时的色谱,简化了仪器方法并提高了表型组和非目标代谢组研究的分析通量。
  • 了解石油的分子组成可以预测其表现和性质以及环境特征。采用15T高场磁共振质谱仪可以进行复杂分子分类,解决了石油加工中的问题。

Learn more about Applications

solariX instruments: Forging Productivity from Innovation

Bruker's solariX XR and solariX 2xR are the result of our tradition of technological innovation. These instruments' core technologies include a ParaCell Detector, Absorption Mode Processing and magnetron control techniques. Together with unmatched mass accuracy this enables routine Isotopic Fine Structure (IFS) analysis for a broad mass range. A wide range of source technologies available for the solariX series allow application of these techniques to a wide variety of samples for flexible experiment and workflow design.

Patented ParaCell detector

The ParaCell is the enabling technology for solariX XR and 2xR. This detector concept is a departure from traditional MRMS cell strategies and provides uncommon broadband ion stability resulting in resolution orders of magnitude above other detection schemes. The ParaCell in combination with Absorption Mode Processing algorithms is the prerequisite for routine access to Isotopic Fine Structure (IFS) Information.

2xR technology realizes scientific visions and increased prodcuctivity

Brukers 2xR solariX instruments uses magnetron control technology and a newly developed, high sensitivity, low noise preamplifier, realizing scientists long standing vision to exploit harmonics detection schemes  and thus increasing the experimental speed and instrument productivity.

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Optional ESI/MALDI dual source

solariX series instruments allow for operation of a unique ESI/MALDI dual source. This optional source can either run liquid samples introduced via the Electrospray ionization (ESI) source or from MALDI samples. This highly sensitive MALDI source uses  Brukers SmartBeam-II™ laser technology and provides several small focus diameters for various applications with different sample preparation techniques. Fast switchover between MALDI and ESI operation is controlled by a software pushbutton, so even simultaneous ESI/MALDI operation is possible.

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Discover previously hidden information to proof your results

Bruker's eXtreme Resolution Magnetic Resonance Mass Spectrometry (MRMS) technology enables scientists to see vital "hidden" information that is missing in data from other types of mass spectrometers. This advanced technology addresses the needs of specialists in a variety of focus areas that all desire efficient and precise solutions for their analytical problems. The unique value of this technology is Isotopic Fine Structure (IFS), resulting in unmatched confidence for compound identification that previously required guesswork.

High Resolution MALDI imaging

MRMS offers unrivaled mass resolving power and outstanding mass accuracy in the ppb range. This results in high resolution MALDI imaging data with the ability of straightforward identification of compounds from tissue directly with utmost confidence. Label-free molecular visualization is an enormous advantage in comparison to radioactive labeling procedures, such as whole-body autoradiography.

MALDI Imaging

Molecular Drug Imager: label-free compound mapping to support ADMET studies

Molecular Drug Imager is a complete solution for label-free distribution monitoring of drug candidates and multi-generational metabolites. In silico metabolite prediction interfaces with MALDI Imaging results from 7T solariX XR for automated mapping of reactive metabolites. Uncover new biochemical pathways by utilizing the broadband detection capabilities of 7T solariX XR to correlate distributions of drug-related material with changes in endogenous compounds or histopathology.

Molecular Drug Imager

‘Phenotyping’ by Magnetic Resonance Mass Spectrometry (MRMS)

MRMS eXtreme Resolution enables the acceleration of sample throughput in phenomics and discovery metabolomics research by omitting time consuming chromatography. Flow Injection analysis (FIA) or MALDI based workflows provide access to compounds not readily detectable by LC-MS analysis and simultaneously analyze known and unknown metabolites.

Phenotyping

Molecular Classification of Petroleum

A detailed knowledge of the exact chemical composition of crude oil and crude oil fractions is essential for the oil industry. Crude oils with similar or even identical bulk chemical properties can behave completely different. Therefore, detailed information on relative abundances of those problematic compound classes is of major interest to e.g. optimize processes.  Understanding the molecular compositional of petroleum allows for the prediction of its behavior and properties as well as environmental fingerprinting.

Petrolomics

For Research Use Only. Not for Use in Clinical Diagnostic Procedures.