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Structural Biology

Macromolecular Complexes

Bruker provides the tools needed to determine properties of molecular complexes, including the 3D-structure to an atomic level. This helps researchers getting better insights into the fundamental role macromolecular complexes play in all basic life processes.

Insights in cell regulation

Bruker provides the outstanding tools researchers need to determine properties of molecular complexes, including the 3D-structure to an atomic level. This helps getting better deeper insights into the fundamental role macromolecular complexes play in all basic life processes.

Large macromolecular complexes perform many critical roles in the execution and regulation of cellular processes. Our instruments help scientiest understanding the structural interactions and dynamics and of such complexes, which is today’s key focus in advancing our understanding of cellular processes.

Single Crystal X-ray Diffraction (SC-XRD) plays a leading role in the structure determination of large, stable multi-protein complexes at near atomic resolution.

Small-angle X-ray scattering (SAXS) is a widely used, convenient technique to characterize the hydrodynamic properties of large complexes in solution. SAXS is particularly informative where ligand-induced conformational changes occur or protein-protein binding events are involved in the activity of the system.