Resolution in a new dimension for solving challenges of society

The new GHz-class NMR technology is now enabling novel research in functional structural biology of proteins and protein complexes.

1.2 GHz at the Max-Planck Institute for Biophysical Chemistry in Göttingen

Analysis of biomolecules in solid and liquid phases using NMR spectroscopy

Research includes the structures, dynamics and function of important globular proteins, membrane proteins and protein complexes.

Ultra-high field NMR is also unique in that it can study the properties and interactions of intrinsically disordered proteins (IDPs), which make up 30-50% of the human proteome. IDPs play a crucial functional rule in fundamental cell biology, and they are also implicated in many instances of disease biology.

Prof. Dr. Christian Griesinger and Prof. Dr. Markus Zweckstetter gave us an interesting insight about their work with the new 1.2 GHz How do molecules behave under disease conditions? How can we use this knowledge to find cures for disease like Alzheimer and Parkinson.