rapifleX MPP Publications

rapifleX MPP Publications

rapifleX MALDI PharmaPulse Publications 

Title Author Publication Link
Screening of DUB activity and specificity by MALDI-TOF mass spectrometry Ritorto, M.S.; Ewan, R. et al. Nat Commun. 2014 Aug 27;5:4763 https://www.nature.com/articles/ncomms5763
The Evolution of MALDI-TOF Mass Spectrometry toward Ultra-High-Throughput Screening: 1536-Well Format and Beyond Haslam, C.; Hellicar, J. et al. J.Biomol. Screen. 2016, 21, 176–186 https://doi.org/10.1177/1087057115608605
A Systematic Investigation of the Best Buffers for Use in Screening by MALDI–Mass Spectrometry Chandler, J.; Haslam, C. et al. J. Biomol. Screen. 2016, 22, 1262-1269 https://doi.org/10.1177/1087057116681726
Integration of an In Situ MALDI-Based High-Throughput Screening Process: A Case Study with Receptor Tyrosine Kinase c-MET Beeman, K.; Baumgartner, J. et al. SLAS Disc. 2017, 22, 1203–1210 https://doi.org/10.1177/2472555217727701
Identifying Inhibitors of Inflammation: A Novel High-Throughput MALDI-TOF Screening Assay for Salt-Inducible Kinases (SIKs) Heap, R. E.; Hope, A. G. et al. SLAS Disc. 2017, 10, 1193–1202 https://doi.org/10.1177/2472555217717473
Identification of Small-Molecule Noncovalent Binders Utilizing SAMDI Technology VanderPorten, E.; Scholle, M. et al. SLAS Discov. 2017, 22(10):1211-1217 https://doi.org/10.1177/2472555217712761
Establishing MALDI-TOF as Versatile Drug Discovery Readout to Dissect the PTP1B Enzymatic Reaction Winter, M.; Bretschneider, T. et al. SLAS Discov. 2018, 10, 1-13 https://doi.org/10.1177/2472555218759267
Mapping the dark space of chemical reactions with extended nanomole synthesis and MALDI-TOF MS Lin, S.; Dikler, S. et al. Science 2018, 10.1126/Science.aar6236 https://science.sciencemag.org/content/361/6402/eaar6236
The MALDI-TOF E2/E3 Ligase Assay as Universal Tool for Drug Discovery in the Ubiquitin Pathway De Cesare, V.; Johnson, C. et al. Cell Chemical Biology 2018 https://doi.org/10.1016/j.chembiol.2018.06.004
Automated MALDI Target Preparation Concept: Providing Ultra-High-Throughput Mass Spectrometry–Based Screening for Drug Discovery Winter, M.; Ries, R. et al. SLAS Technology 2018 https://doi.org/10.1177/2472630318791981
Chemical Derivatization Enables MALDI-TOF-Based High-Throughput Screening for Microbial Trimethylamine (TMA)-Lyase Inhibitors Winter, M.; Bretschneider T. et al. SLAS Discovery 2019 https://doi.org/10.1177/2472555219838216

 

For Research Use Only. Not for use in clinical diagnostic procedures.