SCiLS™ Lab Bibliography

Title Author Publication Link
Impact of spatial metabolomics on immune-microenvironment in oral cancer prognosis: a clinical report. Bag S, Oetjen J et al. Mol Cell Biochem 2023
Spatial resolution of renal amyloid deposits through MALDI-MSI: a combined digital and molecular approach to monoclonal gammopathies. Bindi G, Smith A et al. J Clin Pathol 2023
Rewiring of the N-Glycome with prostate cancer progression and therapy resistance. Butler W, McDowell C et al. NPJ Precis Oncol 2023;7(1):22
3D bioprinted colorectal cancer models based on hyaluronic acid and signalling glycans. Cadamuro F, Marongiu L et al. Carbohydr Polym 2023;302:120395
A Comparison of Different Sample Processing Protocols for MALDI Imaging Mass Spectrometry Analysis of Formalin-Fixed Multiple Myeloma Cells. Casadonte R, Kriegsmann J et al. Cancers (Basel) 2023;15(3)
Imaging Mass Spectrometry for the Classification of Melanoma Based on BRAF/NRAS Mutational Status. Casadonte R, Kriegsmann M et al. Int J Mol Sci 2023;24(6)
MALDI-IHC-Guided In-Depth Spatial Proteomics: Targeted and Untargeted MSI Combined. Claes BSR, Krestensen KK et al. Anal Chem 2023;95(4):2329-2338
In Situ Imaging of O-Linked β-N-Acetylglucosamine Using On-Tissue Hydrolysis and MALDI Mass Spectrometry. Escobar EE, Seeley EH et al. Cancers (Basel) 2023;15(4)
Longitudinal spatial mapping of lipid metabolites reveals pre-symptomatic changes in the hippocampi of Huntington's disease transgenic mice. Farzana F, McConville MJ et al. Neurobiol Dis 2023;176:105933
MALDI mass spectrometry imaging shows a gradual change in the proteome landscape during mouse ovarian folliculogenesis. Fiorentino G, Smith A et al. Mol Hum Reprod 2023;29(4)
Titania Nanosheet as a Matrix for Surface-Assisted Laser Desorption/Ionization Mass Spectrometry Analysis and Imaging. Gao C, Wang Y et al. Anal Chem 2023;95(2):650-658
MALDI Imaging, a Powerful Multiplex Approach to Decipher Intratumoral Heterogeneity: Combined Hepato-Cholangiocarcinomas as Proof of Concept. Gigante E, Cazier H et al. Cancers (Basel) 2023;15(7)
Characterization of Hormone Receptor and HER2 Status in Breast Cancer Using Mass Spectrometry Imaging. Gonçalves JPL, Bollwein C et al. Int J Mol Sci 2023;24(3)
Optimized protocol for MALDI MSI of N-glycans using an on-tissue digestion in fresh frozen tissue sections. Grgic A ,Krestensen KK ,Heeren RMA Sci Rep 2023;13(1):2776
Divide and Conquer: A Flexible Deep Learning Strategy for Exploring Metabolic Heterogeneity from Mass Spectrometry Imaging Data. Guo L, Dong J et al. Anal Chem 2023;95(3):1924-32
Sample preparation for lipid analysis of intra-articular adipose tissue by using matrix-assisted laser desorption/ionization imaging. Haartmans MJJ, Claes BSR et al. Anal Biochem 2023;662:115018
Tumor ratio of unsaturated to saturated sulfatide species is associated with disease-free survival in intrahepatic cholangiocarcinoma. Huizing L, Chen L et al. Cell Oncol (Dordr) 2023
Investigation of Phospholipid Differences in Valproic Acid-Induced Autistic Mouse Model Brain Using Mass Spectrometry Imaging. Jang HJ, Kwon KJ et al. Metabolites 2023;13(2)
Effect of Micro-Patterned Mucin on Quinolone and Rhamnolipid Profiles of Mucoid Pseudomonas aeruginosa under Antibiotic Stress. Jia J, Parmar D et al. ACS Infect Dis 2023;9(1):150-161
Classification of Pancreatic Ductal Adenocarcinoma Using MALDI Mass Spectrometry Imaging Combined with Neural Networks. Kanter F, Lellmann J et al. Cancers (Basel) 2023;15(3)
In Situ Self-Assembled Formation of Nitrogen-Rich Ag@Ti3C2 Film for Sensitive Detection and Spatial Imaging of Pesticides with Laser Desorption/Ionization Mass Spectrometry (LDI-MS). Li W, He Q et al. ACS Appl Mater Interfaces 2023;15(14):18402-18413
Spatial metabolomics reveals skeletal myofiber subtypes. Luo L, Ma W et al. Sci Adv 2023;9(5):eadd0455
Applications and continued evolution of glycan imaging mass spectrometry. McDowell CT, Lu X et al. Mass Spectrom Rev 2023;42(2):674-705
Targeting succinate metabolism to decrease brain injury upon mechanical thrombectomy treatment of ischemic stroke. Mottahedin A, Prag HA et al. Redox Biol 2023;59:102600
Lipidized PrRP Analog Exhibits Strong Anti-Obesity and Antidiabetic Properties in Old WKY Rats with Obesity and Glucose Intolerance. Mráziková L, Hojná S et al. Nutrients 2023;15(2)
Monoisotopic silver nanoparticles-based mass spectrometry imaging of human bladder cancer tissue: Biomarker discovery. Ossoliński K, Ruman T et al. Adv Med Sci 2023;68(1):38-45
Spatially Resolved Molecular Approaches for the Characterisation of Non-Invasive Follicular Tumours with Papillary-like Features (NIFTPs). Piga I, L'Imperio V et al. Int J Mol Sci 2023;24(3)
Fast and Reproducible Matrix Deposition for MALDI Mass Spectrometry Imaging with Improved Glass Sublimation Setup. Shanmugaraj N, Rutten T et al. J Am Soc Mass Spectrom 2023;34(3):513-517
Development of Spheroid-FPOP: An In-Cell Protein Footprinting Method for 3D Tumor Spheroids. Shortt RL, Wang Y et al. J Am Soc Mass Spectrom 2023;34(3):417-425
A multimodal pipeline using NMR spectroscopy and MALDI-TOF mass spectrometry imaging from the same tissue sample. Tressler CM, Ayyappan V et al. NMR Biomed 2023;36(4):e4770
Detection of early proteomic alterations in 5xFAD Alzheimer's disease neonatal mouse model via MALDI-MSI. Uras I, Karayel-Basar M et al. Alzheimers Dement 2023
Hepatic glutamine synthetase controls N5-methylglutamine in homeostasis and cancer. Villar VH, Allega MF et al. Nat Chem Biol 2023;19(3):292-300
Commensal microbiome promotes hair follicle regeneration by inducing keratinocyte HIF-1α signaling and glutamine metabolism. Wang G, Sweren E et al. Sci Adv 2023;9(1):eabo7555
Mobility-resolved broadband dissociation and parallel reaction monitoring for laser desorption/ionization-mass spectrometry - Tattoo pigment identification supported by trapped ion mobility spectrometry. Wolf C, Behrens A et al. Anal Chim Acta 2023;1242:340796
Region-resolved multi-omics of the mouse eye. Xiang H, Zhang B et al. Cell Rep 2023;42(2):112121
Exposure to isocyanates predicts atopic dermatitis prevalence and disrupts therapeutic pathways in commensal bacteria. Zeldin J, Chaudhary PP et al. Sci Adv 2023;9(1):eade8898
Tandemly duplicated CYP82Ds catalyze 14-hydroxylation in triptolide biosynthesis and precursor production in Saccharomyces cerevisiae. Zhang Y, Gao J et al. Nat Commun 2023;14(1):875

SCiLS Lab Bibliography 2022

Title Author Publication Link
The fatal trajectory of pulmonary COVID-19 is driven by lobular ischemia and fibrotic remodelling. Ackermann M, Kamp JC et al. EBioMedicine 2022;85:104296
A Protocol for the Acquisition of Comprehensive Proteomics Data from Single Cases Using Formalin-Fixed Paraffin Embedded Sections. Acland M, Mittal P et al. Methods Protoc 2022;5(4)
Venoms for all occasions: The functional toxin profiles of different anatomical regions in sea anemones are related to their ecological function. Ashwood LM, Undheim EAB et al. Mol Ecol 2022;31(3):866-883
An overview of image registration for aligning mass spectrometry imaging with clinically relevant imaging modalities. Balluff B ,Heeren RMA ,Race AM J Mass Spectrom Adv Clin Lab 2022;23:26-38
Mass spectrometry-based metabolomics in microbiome investigations. Bauermeister A, Mannochio-Russo H et al. Nat Rev Microbiol 2022;20(3):143-160
Fallopian tube secreted protein affects ovarian metabolites in high grade serous ovarian cancer. Bergsten TM, Levy SE et al. Front Cell Dev Biol 2022;10:1042734
Mass spectrometry imaging to explore molecular heterogeneity in cell culture. Bien T, Koerfer K et al. Proc Natl Acad Sci U S A 2022;119(29):e2114365119
Integrating age, BMI, and serum N-glycans detected by MALDI mass spectrometry to classify suspicious mammogram findings as benign lesions or breast cancer. Blaschke CRK, Hill EG et al. Sci Rep 2022;12(1):20801
Neuroinflammation in neuronopathic Gaucher disease: Role of microglia and NK cells, biomarkers, and response to substrate reduction therapy. Boddupalli CS, Nair S et al. Elife 2022;11
MALDI Mass Spectrometry Imaging for the Distinction of Adenocarcinomas of the Pancreas and Biliary Tree. Bollwein C, Gonҫalves JPL et al. Molecules 2022;27(11)
Evaluation of Quantitative Platforms for Single Target Mass Spectrometry Imaging. Bowman AP, Sawicki J et al. Pharmaceuticals (Basel) 2022;15(10)
High-Mannose N-Glycans as Malignant Progression Markers in Early-Stage Colorectal Cancer. Boyaval F, Dalebout H et al. Cancers (Basel) 2022;14(6)
Spatial metabolomics reveals upregulation of several pyrophosphate-producing pathways in cortical bone of Hyp mice. Buck A, Prade VM et al. JCI Insight 2022;7(20)
Metabolic tumor constitution is superior to tumor regression grading for evaluating response to neoadjuvant therapy of esophageal adenocarcinoma patients. Buck A, Prade VM et al. J Pathol 2022;256(2):202-213
Orthotopic Glioblastoma Models for Evaluation of the Clinical Target Volume Concept. Bütof R, Hönscheid P et al. Cancers (Basel) 2022;14(19)
Protective Mechanism of Polygonum perfoliatum L. Extract on Chronic Alcoholic Liver Injury Based on UHPLC-QExactive Plus Mass Spectrometry Lipidomics and MALDI-TOF/TOF Mass Spectrometry Imaging. Chen H, Peng L et al. Foods 2022;11(11)
In situ metabolic profile and spatial distribution of ocular tissues: New insights into dry eye disease. Chen X, Zhang C et al. Ocul Surf 2022;24:51-63
Unraveling metabolic alterations in transgenic mouse model of Alzheimer's disease using MALDI MS imaging with 4-aminocinnoline-3-carboxamide matrix. Chen Y, Hu D et al. Anal Chim Acta 2022;1192:339337
Spatially revealed perfluorooctane sulfonate-induced nephrotoxicity in mouse kidney using atmospheric pressure MALDI mass spectrometry imaging. Chen Y, Jiang L et al. Sci Total Environ 2022;838(Pt 3):156380
Glycosphingolipids are mediators of cancer plasticity through independent signaling pathways. Cumin C, Huang YL et al. Cell Rep 2022;40(7):111181
'On the Spot' Digital Pathology of Breast Cancer Based on Single-Cell Mass Spectrometry Imaging. Cuypers E, Claes BSR et al. Anal Chem 2022;94(16):6180-6190
Correlating Mass Spectrometry Imaging and Liquid Chromatography-Tandem Mass Spectrometry for Tissue-Based Pharmacokinetic Studies. Dannhorn A, Kazanc E et al. Metabolites 2022;12(3)
Evaluation of Formalin-Fixed and FFPE Tissues for Spatially Resolved Metabolomics and Drug Distribution Studies. Dannhorn A, Swales JG et al. Pharmaceuticals (Basel) 2022;15(11)
Resolving the developmental distribution patterns of polyphenols and related primary metabolites in bilberry (Vaccinium myrtillus) fruit. Dare AP, Günther CS et al. Food Chem 2022;374:131703
Multicenter Evaluation of Tissue Classification by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging. Deininger SO, Bollwein C et al. Anal Chem 2022;94(23):8194-8201
Novel Combined Enzymatic Approach to Analyze Nonsialylated N-Linked Glycans through MALDI Imaging Mass Spectrometry. DelaCourt AT, Liang H et al. J Proteome Res 2022;21(8):1930-1938
Spatial Multiomics of Lipids, N-Glycans, and Tryptic Peptides on a Single FFPE Tissue Section. Denti V, Capitoli G et al. J Proteome Res 2022;21(11):2798-2809
iMS2Net: A multiscale networking methodology to decipher metabolic synergy of organism. Dong J, Peng Q et al. iScience 2022;25(9):104896
MALDI-2 and t-MALDI-2 Mass Spectrometry Imaging. Dreisewerd K ,Bien T ,Soltwisch J Methods Mol Biol 2022;2437:21-40
Spatial analysis of the glioblastoma proteome reveals specific molecular signatures and markers of survival. Duhamel M, Drelich L et al. Nat Commun 2022;13(1):6665
Dissecting the Kinetic Mechanism of Human Lysine Methyltransferase 2D and Its Interactions with the WRAD2 Complex. Edwardes LV, Caswell SJ et al. Biochemistry 2022;61(18):1974-1987
Sphingomyelinases in retinas and optic nerve heads: Effects of ocular hypertension and ischemia. Fan J, Liu J et al. Exp Eye Res 2022;224:109250
Region-Specific and Age-Dependent Multitarget Effects of Acetylcholinesterase Inhibitor Tacrine on Comprehensive Neurotransmitter Systems. Fridjonsdottir E, Vallianatou T et al. ACS Chem Biol 2022;17(1):147-158
Device-Controlled Microcondensation for Spatially Confined On-Tissue Digests in MALDI Imaging of N-Glycans. Fülöp A, Marsching C et al. Pharmaceuticals (Basel) 2022;15(11)
Mass Spectrometry Imaging Spatial Tissue Analysis toward Personalized Medicine. Gonçalves JPL ,Bollwein C ,Schwamborn K Life (Basel) 2022;12(7)
MALDI-MSI: A Powerful Approach to Understand Primary Pancreatic Ductal Adenocarcinoma and Metastases. Gonçalves JPL, Bollwein C et al. Molecules 2022;27(15)
High Spatial Resolution MALDI Imaging Mass Spectrometry of Fresh-Frozen Bone. Good CJ, Neumann EK et al. Anal Chem 2022;94(7):3165-3172
In Situ N-Glycosylation Signatures of Epithelial Ovarian Cancer Tissue as Defined by MALDI Mass Spectrometry Imaging. Grzeski M, Taube ET et al. Cancers (Basel) 2022;14(4)
Multimodal Imaging Mass Spectrometry of Murine Gastrointestinal Tract with Retained Luminal Content. Guiberson ER, Good CJ et al. J Am Soc Mass Spectrom 2022;33(6):1073-1076
iSegMSI: An Interactive Strategy to Improve Spatial Segmentation of Mass Spectrometry Imaging Data. Guo L, Liu X et al. Anal Chem 2022;94(42):14522-14529
Cryo-ultramicrotomy and Mass Spectrometry Imaging Analysis of Nudibranch Microstructures. Hamilton BR, Chan W et al. J Am Soc Mass Spectrom 2022;33(3):592-597
Pharmacological inhibition of MERTK induces in vivo retinal degeneration: a multimodal imaging ocular safety assessment. Hamm G, Maglennon G et al. Arch Toxicol 2022;96(2):613-624
On-tissue derivatization for isomer-specific mass spectrometry imaging and relative quantification of monosaccharides in biological tissues. Han Y, Zhao Y et al. Anal Chim Acta 2022;1225:340241
Acute lyme disease IgG N-linked glycans contrast the canonical inflammatory signature. Haslund-Gourley BS, Grauzam S et al. Front Immunol 2022;13:949118
Multimodal Lung Cancer Subtyping Using Deep Learning Neural Networks on Whole Slide Tissue Images and MALDI MSI. Janßen C, Boskamp T et al. Cancers (Basel) 2022;14(24)
Robust subtyping of non-small cell lung cancer whole sections through MALDI mass spectrometry imaging. Janßen C, Boskamp T et al. Proteomics Clin Appl 2022;16(4):e2100068
Visualizing the spatial distribution of functional metabolites in Forsythia suspensa at different harvest stages by MALDI mass spectrometry imaging. Jing F, Wang L et al. Fitoterapia 2022;162:105285
Spatial quantitation of antibiotics in bone tissue compartments by laser-capture microdissection coupled with UHPLC-tandem mass spectrometry. Kaya F, Zimmerman MD et al. Anal Bioanal Chem 2022;414(23):6919-6927
Physiological constraints dictate toxin spatial heterogeneity in snake venom glands. Kazandjian TD, Hamilton BR et al. BMC Biol 2022;20(1):148
Mass spectrometry imaging spatially identifies complex-type N-glycans as putative cartilage degradation markers in human knee osteoarthritis tissue. Lee YR, Briggs MT et al. Anal Bioanal Chem 2022;414(26):7597-7607
Multi-omics profiling of collagen-induced arthritis mouse model reveals early metabolic dysregulation via SIRT1 axis. Li L, Freitag J et al. Sci Rep 2022;12(1):11830
Reduced Hemoglobin Signal and Improved Detection of Endogenous Proteins in Blood-Rich Tissues for MALDI Mass Spectrometry Imaging. Lin M ,Eberlin LS ,Seeley EH J Am Soc Mass Spectrom 2022;33(2):296-303
Deep multilayer brain omics identifies the potential involvement of menopause molecular networks in Gliomas' disease progression. Liu C, Zhang W et al. FASEB J 2022;36(10):e22570
High-throughput screening and spatial profiling of low-mass pesticides using a novel Ti3C2 MXene nanowire (TMN) as MALDI MS matrix. Ma C, Wang X et al. Chemosphere 2022;286(Pt 2):131826
Sample preparation optimization of insects and zebrafish for whole-body mass spectrometry imaging. Ma L, Xie Q et al. Anal Bioanal Chem 2022;414(16):4777-4790
Matrix-assisted laser desorption/ionization mass spectrometry imaging reveals Spatial-Temporal-Content" changes of parishins in Gastrodiae Rhizoma during the steaming process." Ma T, Sun C et al. Food Res Int 2022;162(Pt B):112092
Quaternized Acridine Maleimide MALDI Probe Enables Mass Spectrometry Imaging of Thiols. Ma Z, Yuan J et al. Anal Chem 2022;94(43):14917-14924
On-tissue spatially resolved glycoproteomics guided by N-glycan imaging reveal global dysregulation of canine glioma glycoproteomic landscape. Malaker SA, Quanico J et al. Cell Chem Biol 2022;29:30-42.e4
CD138 Is Expressed in Different Entities of Salivary Gland Cancer and Their Lymph Node Metastases and Therefore Represents a Potential Therapeutic Target. Mayer M, Nachtsheim L et al. Int J Mol Sci 2022;23(16)
Utilizing imaging mass spectrometry to analyze microbial biofilm chemical responses to exogenous compounds. McCaughey CS, Trebino MA et al. Methods Enzymol 2022;665:281-304
Structural Characterization and Spatial Mapping of Tetrodotoxins in Australian Polyclads. McNab JM, Briggs MT et al. Mar Drugs 2022;20(12)
Pro-inflammatory IgG1 N-glycan signature correlates with primary graft dysfunction onset in COPD patients. McQuiston A, Scott D et al. Transpl Immunol 2022;71:101491
Protein Alterations in Cardiac Ischemia/Reperfusion Revealed by Spatial-Omics. Mezger STP, Mingels AMA et al. Int J Mol Sci 2022;23(22)
Mass Spectrometry Imaging of Lipids Using MALDI Coupled with Plasma-Based Post-Ionization on a Trapped Ion Mobility Mass Spectrometer. Michael JA, Mutuku SM et al. Anal Chem 2022;94(50):17494-17503
Chemical traits of cerebral amyloid angiopathy in familial British-, Danish-, and non-Alzheimer's dementias. Michno W, Koutarapu S et al. J Neurochem 2022;163(3):233-246
Structural amyloid plaque polymorphism is associated with distinct lipid accumulations revealed by trapped ion mobility mass spectrometry imaging. Michno W, Wehrli PM et al. J Neurochem 2022;160(4):482-498
Multiomic Mass Spectrometry Imaging to Advance Future Pathological Understanding of Ocular Disease. Millar J, Ozaki E et al. Metabolites 2022;12(12)
Unravelling Prostate Cancer Heterogeneity Using Spatial Approaches to Lipidomics and Transcriptomics. Mutuku SM, Spotbeen X et al. Cancers (Basel) 2022;14(7)
Imaging Mass Spectrometry Reveals Alterations in N-Linked Glycosylation That Are Associated With Histopathological Changes in Nonalcoholic Steatohepatitis in Mouse and Human. Ochoa-Rios S, O'Connor IP et al. Mol Cell Proteomics 2022;21(5):100225
Mass Spectrometry-Based Differentiation of Oral Tongue Squamous Cell Carcinoma and Nontumor Regions With the SpiderMass Technology. Ogrinc N, Attencourt C et al. Front Oral Health 2022;3:827360
The metabolic landscape in chronic rotator cuff tear reveals tissue-region-specific signatures. Olie CS, van Zeijl R et al. J Cachexia Sarcopenia Muscle 2022;13(1):532-543
Mass spectrometry imaging discriminates glioblastoma tumor cell subpopulations and different microvascular formations based on their lipid profiles. O'Neill KC, Liapis E et al. Sci Rep 2022;12(1):17069
Caffeine intake exerts dual genome-wide effects on hippocampal metabolism and learning-dependent transcription. Paiva I, Cellai L et al. J Clin Invest 2022;132(12)
Hornerin deposits in neuronal intranuclear inclusion disease: direct identification of proteins with compositionally biased regions in inclusions. Park H, Yamanaka T et al. Acta Neuropathol Commun 2022;10(1):28
Induction of Liver Size Reduction in Zebrafish Larvae by the Emerging Synthetic Cannabinoid 4F-MDMB-BINACA and Its Impact on Drug Metabolism. Park YM, Dahlem C et al. Molecules 2022;27(4)
Multi-Class Cancer Subtyping in Salivary Gland Carcinomas with MALDI Imaging and Deep Learning. Pertzborn D, Arolt C et al. Cancers (Basel) 2022;14(17)
Spatially resolved multi-omics deciphers bidirectional tumor-host interdependence in glioblastoma. Ravi VM, Will P et al. Cancer Cell 2022;40(6):639-655.e13
Imaging mass spectrometry reveals complex lipid distributions across Staphylococcus aureus biofilm layers. Rivera ES, Weiss A et al. J Mass Spectrom Adv Clin Lab 2022;26:36-46
Metabolic Links to Socioeconomic Stresses Uniquely Affecting Ancestry in Normal Breast Tissue at Risk for Breast Cancer. Rujchanarong D, Scott D et al. Front Oncol 2022;12:876651
Atlas of exercise metabolism reveals time-dependent signatures of metabolic homeostasis. Sato S, Dyar KA et al. Cell Metab 2022;34(2):329-345.e8
MALDI imaging mass spectrometry: an emerging tool in neurology. Schnackenberg LK, Thorn DA et al. Metab Brain Dis 2022;37(1):105-121
Bioactive lipid screening during respiratory tract infections with bacterial and viral pathogens in mice. Schultz D, Cuypers F et al. Metabolomics 2022;18(6):39
GlycoFibroTyper: A Novel Method for the Glycan Analysis of IgG and the Development of a Biomarker Signature of Liver Fibrosis. Scott DA, Wang M et al. Front Immunol 2022;13:797460
A non-dividing cell population with high pyruvate dehydrogenase kinase activity regulates metabolic heterogeneity and tumorigenesis in the intestine. Sebastian C, Ferrer C et al. Nat Commun 2022;13(1):1503
S100A4 exerts robust mucosal adjuvant activity for co-administered antigens in mice. Sen Chaudhuri A, Yeh YW et al. Mucosal Immunol 2022;15(5):1028-1039
Spatial metabolomics for evaluating response to neoadjuvant therapy in non-small cell lung cancer patients. Shen J, Sun N et al. Cancer Commun (Lond) 2022;42(6):517-535
Imaging Mass Spectrometry (IMS) for drug discovery and development survey: Results on methods, applications and regulatory compliance. Solon E, Groseclose MR et al. Drug Metab Pharmacokinet 2022;43:100438
MALDI Mass Spectrometry Imaging Highlights Specific Metabolome and Lipidome Profiles in Salivary Gland Tumor Tissues. Sommella E, Salviati E et al. Metabolites 2022;12(6)
Spatially resolved characterization of tissue metabolic compartments in fasted and high-fat diet livers. Stopka SA, van der Reest J et al. PLoS One 2022;17(9):e0261803
Method To Visualize the Intratumor Distribution and Impact of Gemcitabine in Pancreatic Ductal Adenocarcinoma by Multimodal Imaging. Strittmatter N, Richards FM et al. Anal Chem 2022;94(3):1795-1803
MALDI Mass Spectrometry Imaging of Lipids on Free-Floating Brain Sections and Immunohistochemically Colocalized Markers of Neurodegeneration. Strnad Š, Strnadová V et al. Methods Mol Biol 2022;2437:229-239
Visualizing the spatial distribution and alteration of metabolites in continuously cropped Salvia miltiorrhiza Bge using MALDI-MSI. Sun C, Cui L et al. J Pharm Anal 2022;12(5):719-724
FT-ICR Mass Spectrometry Imaging at Extreme Mass Resolving Power Using a Dynamically Harmonized ICR Cell with 1ω or 2ω Detection. Tiquet M, La Rocca R et al. Anal Chem 2022;94(26):9316-9326
Exposure to solar ultraviolet radiation establishes a novel immune suppressive lipidome in skin-draining lymph nodes. Tse BCY, Ferguson AL et al. Front Immunol 2022;13:1045731
Mapping of MeLiM melanoma combining ICP-MS and MALDI-MSI methods. Vaníčková L, Do T et al. Int J Biol Macromol 2022;203:583-592
Spatial Mapping of Plant N-Glycosylation Cellular Heterogeneity Inside Soybean Root Nodules Provided Insights Into Legume-Rhizobia Symbiosis. Veličković D, Liao YC et al. Front Plant Sci 2022;13:869281
PALP: A rapid imaging technique for stratifying ferroptosis sensitivity in normal and tumor tissues in situ. Wang F, Graham ET et al. Cell Chem Biol 2022;29(1):157-170.e6
Analyzing cell-type-specific dynamics of metabolism in kidney repair. Wang G, Heijs B et al. Nat Metab 2022;4(9):1109-1118
Spatial dynamic metabolomics identifies metabolic cell fate trajectories in human kidney differentiation. Wang G, Heijs B et al. Cell Stem Cell 2022;29(11):1580-1593.e7
PARP-inhibition reprograms macrophages toward an anti-tumor phenotype. Wang L, Wang D et al. Cell Rep 2022;41(2):111462
A simple preparation step to remove excess liquid lipids in white adipose tissue enabling improved detection of metabolites via MALDI-FTICR imaging MS. Wang Q, Sun N et al. Histochem Cell Biol 2022;157(5):595-605
Visualizing the Distribution of Lipids in Peanut Seeds by MALDI Mass Spectrometric Imaging. Wang X, Chen Y et al. Foods 2022;11(23)
Klebsiella pneumoniae induces host metabolic stress that promotes tolerance to pulmonary infection. Wong Fok Lung T, Charytonowicz D et al. Cell Metab 2022;34(5):761-774.e9
Three-Dimensional Mass Spectrometry Imaging Reveals Distributions of Lipids and the Drug Metabolite Associated with the Enhanced Growth of Colon Cancer Cell Spheroids Treated with Triclosan. Xie P, Zhang H et al. Anal Chem 2022;94(40):13667-13675
Impact of Skin Tissue Collection Method on Downstream MALDI-Imaging. Yadav M, Chaudhary PP et al. Metabolites 2022;12(6)
Optimization of Zebrafish Larvae Sectioning for Mass Spectrometry Imaging. Yang J, Rendino L et al. Pharmaceuticals (Basel) 2022;15(10)
In situ mass spectrometry imaging reveals heterogeneous glycogen stores in human normal and cancerous tissues. Young LEA, Conroy LR et al. EMBO Mol Med 2022;14(11):e16029
Mapping Glucose Uptake, Transport and Metabolism in the Bovine Lens Cortex. Zahraei A, Guo G et al. Front Physiol 2022;13:901407
Enhanced Spatial Mapping of Histone Proteoforms in Human Kidney Through MALDI-MSI by High-Field UHMR-Orbitrap Detection. Zemaitis KJ, Veličković D et al. Anal Chem 2022;94(37):12604-12613
On-tissue amidation of sialic acid with aniline for sensitive imaging of sialylated N-glycans from FFPE tissue sections via MALDI mass spectrometry. Zhang H, Shi X et al. Anal Bioanal Chem 2022;414(18):5263-5274
Generation and multiomic profiling of a TP53/CDKN2A double-knockout gastroesophageal junction organoid model. Zhao H, Cheng Y et al. Sci Transl Med 2022;14(673):eabq6146
Multiplatform Metabolomics Studies of Human Cancers With NMR and Mass Spectrometry Imaging. Zhong AB, Muti IH et al. Front Mol Biosci 2022;9:785232
Application of artificial intelligence in the diagnosis and prognostic prediction of ovarian cancer. Zhou J, Cao W et al. Comput Biol Med 2022;146:105608

SCiLS Lab Bibliography 2021

Title Author Publication Link
Peak learning of mass spectrometry imaging data using artificial neural networks. Abdelmoula WM, Lopez BG et al. Nat Commun 2021;12(1):5544
GD3 synthase deletion alters retinal structure and impairs visual function in mice. Abreu CA, Teixeira-Pinheiro LC et al. J Neurochem 2021;158:694-709
Spatial differentiation of metabolism in prostate cancer tissue by MALDI-TOF MSI. Andersen MK, Høiem TS et al. Cancer Metab 2021;9(1):9
Electroblotting through Enzymatic Membranes to Enhance Molecular Tissue Imaging. Andrews WT, Bickner AN et al. J Am Soc Mass Spectrom 2021;32:1689-1699
Visualizing Cholesterol in the Brain by On-Tissue Derivatization and Quantitative Mass Spectrometry Imaging. Angelini R, Yutuc E et al. Anal Chem 2021;93(11):4932-4943
Machine learning for grading and prognosis of esophageal dysplasia using mass spectrometry and histological imaging. Beuque M, Martin-Lorenzo M et al. Comput Biol Med 2021;138:104918
Molecular insights into symbiosis-mapping sterols in a marine flatworm-algae-system using high spatial resolution MALDI-2-MS imaging with ion mobility separation. Bien T, Hambleton EA et al. Anal Bioanal Chem 2021;413:2767-2777
Direct N-Glycosylation Profiling of Urine and Prostatic Fluid Glycoproteins and Extracellular Vesicles. Blaschke CRK, Hartig JP et al. Front Chem 2021;9:734280
Cross-Normalization of MALDI Mass Spectrometry Imaging Data Improves Site-to-Site Reproducibility. Boskamp T, Casadonte R et al. Anal Chem 2021;93(30):10584-10592
N-Glycomic Signature of Stage II Colorectal Cancer and Its Association With the Tumor Microenvironment. Boyaval F, van Zeijl R et al. Mol Cell Proteomics 2021;20:100057
GSK-3 Inhibition Is Cytotoxic in Glioma Stem Cells through Centrosome Destabilization and Enhances the Effect of Radiotherapy in Orthotopic Models. Brüning-Richardson A, Shaw GC et al. Cancers (Basel) 2021;13(23)
Use of MALDI Mass Spectrometry Imaging to Identify Proteomic Signatures in Aortic Aneurysms after Endovascular Repair. Buerger M, Klein O et al. Biomedicines 2021;9(9)
Lipidomic Profiling of Clinical Prostate Cancer Reveals Targetable Alterations in Membrane Lipid Composition. Butler LM, Mah CY et al. Cancer Res 2021;81(19):4981-4993
Mass spectrometry imaging of L-[ring-13C6]-labeled phenylalanine and tyrosine kinetics in non-small cell lung carcinoma. Cao J, Balluff B et al. Cancer Metab 2021;9(1):26
Imaging Mass Spectrometry-Based Proteomic Analysis to Differentiate Melanocytic Nevi and Malignant Melanoma. Casadonte R, Kriegsmann M et al. Cancers (Basel) 2021;13(13)
Visualization of HIV-1 reservoir: an imaging perspective. Chapon C, Moysi E et al. Curr Opin HIV AIDS 2021;16(4):232-239
Trends in oligomannosylation and α1,2-mannosidase expression in human cancers. Chatterjee S, Ugonotti J et al. Oncotarget 2021;12(21):2188-2205
Mass spectrometry imaging revealed alterations of lipid metabolites in multicellular tumor spheroids in response to hydroxychloroquine. Chen Y, Wang T et al. Anal Chim Acta 2021;1184:339011
Multiplexed imaging mass spectrometry of the extracellular matrix using serial enzyme digests from formalin-fixed paraffin-embedded tissue sections. Clift CL, Drake RR et al. Anal Bioanal Chem 2021;413:2709-2719
Proteomic Analysis Identifies FNDC1, A1BG, and Antigen Processing Proteins Associated with Tumor Heterogeneity and Malignancy in a Canine Model of Breast Cancer. Cordeiro YG, Mulder LM et al. Cancers (Basel) 2021;13(23)
Muscle metabolic remodelling patterns in Duchenne muscular dystrophy revealed by ultra-high-resolution mass spectrometry imaging. Dabaj I, Ferey J et al. Sci Rep 2021;11(1):1906
N-Glycosylation Patterns Correlate with Hepatocellular Carcinoma Genetic Subtypes. DelaCourt A, Black A et al. Mol Cancer Res 2021;19(11):1868-1877
Reproducible Lipid Alterations in Patient-Derived Breast Cancer Xenograft FFPE Tissue Identified with MALDI MSI for Pre-Clinical and Clinical Application. Denti V, Andersen MK et al. Metabolites 2021;11(9)
Lipidomic Typing of Colorectal Cancer Tissue Containing Tumour-Infiltrating Lymphocytes by MALDI Mass Spectrometry Imaging. Denti V, Mahajneh A et al. Metabolites 2021;11(9)
Lesion Penetration and Activity Limit the Utility of Second-Line Injectable Agents in Pulmonary Tuberculosis. Ernest JP, Sarathy J et al. Antimicrob Agents Chemother 2021;65(10):e0050621
Heterogeneity of Lipid and Protein Cartilage Profiles Associated with Human Osteoarthritis with or without Type 2 Diabetes Mellitus. Eveque-Mourroux MR, Emans PJ et al. J Proteome Res 2021;20(5):2973-2982
Molecular Mapping of Neutral Lipids Using Silicon Nanopost Arrays and TIMS Imaging Mass Spectrometry. Fincher JA, Djambazova KV et al. J Am Soc Mass Spectrom 2021;32(10):2519-2527
Comparison of Osteosarcoma Aggregated Tumour Models with Human Tissue by Multimodal Mass Spectrometry Imaging. Flint LE, Hamm G et al. Metabolites 2021;11(8)
Mass spectrometry imaging identifies abnormally elevated brain l-DOPA levels and extrastriatal monoaminergic dysregulation in l-DOPA-induced dyskinesia. Fridjonsdottir E, Shariatgorji R et al. Sci Adv 2021;7(2)
Connecting structure and function from organisms to molecules in small-animal symbioses through chemo-histo-tomography. Geier B, Oetjen J et al. Proc Natl Acad Sci U S A 2021;118(27)
Integrative Metabolomics Reveals Deep Tissue and Systemic Metabolic Remodeling in Glioblastoma. Gilard V, Ferey J et al. Cancers (Basel) 2021;13(20)
The Impact of Histological Annotations for Accurate Tissue Classification Using Mass Spectrometry Imaging. Gonçalves JPL, Bollwein C et al. Metabolites 2021;11(11)
Lipid Analysis of Fracture Hematoma With MALDI-MSI: Specific Lipids are Associated to Bone Fracture Healing Over Time. Groven RVM, Nauta SP et al. Front Chem 2021;9:780626
Data Filtering and Its Prioritization in Pipelines for Spatial Segmentation of Mass Spectrometry Imaging. Guo L, Hu Z et al. Anal Chem 2021;93(11):4788-4793
Transcriptomic, peptidomic, and mass spectrometry imaging analysis of the brain in the ant Cataglyphis nodus. Habenstein J, Schmitt F et al. J Neurochem 2021;158:391-412
Path to Clonal Theranostics in Luminal Breast Cancers. Hajjaji N, Aboulouard S et al. Front Oncol 2021;11:802177
Complementing Matrix-Assisted Laser Desorption Ionization-Mass Spectrometry Imaging with Chromatography Data for Improved Assignment of Isobaric and Isomeric Phospholipids Utilizing Trapped Ion Mobility-Mass Spectrometry. Helmer PO, Nordhorn ID et al. Anal Chem 2021;93:2135-2143
Registration of Image Modalities for Analyses of Tissue Samples Using 3D Image Modelling. Hermann J, Brehmer K et al. Proteomics Clin Appl 2021;15(1):e1900143
An imaging mass spectrometry atlas of lipids in the human neurologically normal and Huntington's disease caudate nucleus. Hunter M, Demarais NJ et al. J Neurochem 2021;157:2158-2172
Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging of Phospholipid Changes in a Drosophila Model of Early Amyotrophic Lateral Sclerosis. Jang HJ, Le MUT et al. J Am Soc Mass Spectrom 2021;32(10):2536-2545
Biopolymer Patterning-Directed Secretion in Mucoid and Nonmucoid Strains of Pseudomonas aeruginosa Revealed by Multimodal Chemical Imaging. Jia J, Ellis JF et al. ACS Infect Dis 2021;7(3):598-607
Classification of Molecular Subtypes of High-Grade Serous Ovarian Cancer by MALDI-Imaging. Kassuhn W, Klein O et al. Cancers (Basel) 2021;13(7)
Protease-dependent defects in N-cadherin processing drive PMM2-CDG pathogenesis. Klaver EJ, Dukes-Rimsky L et al. JCI Insight 2021;6(24)
Toward Revealing Microcystin Distribution in Mouse Liver Tissue Using MALDI-MS Imaging. Kucheriavaia D, Veličković D et al. Toxins (Basel) 2021;13(10)
Patterns of Carbon-Bound Exogenous Compounds in Patients with Lung Cancer and Association with Disease Pathophysiology. Kunzke T, Prade VM et al. Cancer Res 2021;81(23):5862-5875
MALDI-IMS combined with shotgun proteomics identify and localize new factors in male infertility. Lahiri S, Aftab W et al. Life Sci Alliance 2021;4(3)
Absolute quantification of 2-hydroxyglutarate on tissue by matrix-assisted laser desorption/ionization mass spectrometry imaging for rapid and precise identification of isocitrate dehydrogenase mutations in human glioma. Lan C, Li H et al. Int J Cancer 2021;149(12):2091-2098
Mitochondrial Ndufa4l2 Enhances Deposition of Lipids and Expression of Ca9 in the TRACK Model of Early Clear Cell Renal Cell Carcinoma. Laursen KB, Chen Q et al. Front Oncol 2021;11:783856
Therapeutic Potential of Fosmanogepix (APX001) for Intra-abdominal Candidiasis: from Lesion Penetration to Efficacy in a Mouse Model. Lee A, Wang N et al. Antimicrob Agents Chemother 2021;65
A digital single-molecule nanopillar SERS platform for predicting and monitoring immune toxicities in immunotherapy. Li J, Wuethrich A et al. Nat Commun 2021;12(1):1087
Three-Dimensional Imaging of Whole-Body Zebrafish Revealed Lipid Disorders Associated with Niemann-Pick Disease Type C1. Liang X, Cao S et al. Anal Chem 2021;93:8178-8187
Spatially Resolved Metabolomics and Lipidomics Reveal Salinity and Drought-Tolerant Mechanisms of Cottonseeds. Liu B, Wang X et al. J Agric Food Chem 2021;69(28):8028-8037
Examination of lipid profiles in abdominal fascial healing using MALDI-TOF to identify potential therapeutic targets. Liu H, Cao J et al. J Mass Spectrom Adv Clin Lab 2021;20:35-41
Peptide Signatures for Prognostic Markers of Pancreatic Cancer by MALDI Mass Spectrometry Imaging. Loch FN, Klein O et al. Biology (Basel) 2021;10(10)
Tumor resistance to ferroptosis driven by Stearoyl-CoA Desaturase-1 (SCD1) in cancer cells and Fatty Acid Biding Protein-4 (FABP4) in tumor microenvironment promote tumor recurrence. Luis G, Godfroid A et al. Redox Biol 2021;43:102006
A Mass Spectrometry Imaging Based Approach for Prognosis Prediction in UICC Stage I/II Colon Cancer. Martin B, Gonçalves JPL et al. Cancers (Basel) 2021;13(21)
Rapid visualization of lipopeptides and potential bioactive groups of compounds by combining ion mobility and MALDI imaging mass spectrometry. McCann A, Kune C et al. Drug Discov Today Technol 2021;39:81-88
Imaging Mass Spectrometry and Lectin Analysis of N-Linked Glycans in Carbohydrate Antigen-Defined Pancreatic Cancer Tissues. McDowell CT, Klamer Z et al. Mol Cell Proteomics 2021;20:100012
Study of the Distribution of Acetaminophen and Its Metabolites in Rats, from the Whole-Body to Isolated Organ Levels, by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging after On-Tissue Chemical Derivatization. Merdas M, Lagarrigue M et al. Anal Chem 2021;93(39):13242-13250
Mass Spectrometry Spatial-Omics on a Single Conductive Slide. Mezger STP, Mingels AMA et al. Anal Chem 2021;93:2527-2533
Cancer Tissue Classification Using Supervised Machine Learning Applied to MALDI Mass Spectrometry Imaging. Mittal P, Condina MR et al. Cancers (Basel) 2021;13(21)
Lipid signature of advanced human carotid atherosclerosis assessed by mass spectrometry imaging. Moerman AM, Visscher M et al. J Lipid Res 2021;62:100020
Complementary Lipidomic, Proteomic, and Mass Spectrometry Imaging Approach to the Characterization of the Acute Effects of Radiation in the Non-human Primate Mesenteric Lymph Node after Partial-body Irradiation with Minimal Bone Marrow Sparing. Muller L, Huang W et al. Health Phys 2021;121(4):372-383
Imaging lipids in biological samples with surface-assisted laser desorption/ionization mass spectrometry: A concise review of the last decade. Müller WH, De Pauw E et al. Prog Lipid Res 2021;83:101114
Spatial metabolomics using imaging mass spectrometry to identify the localization of asparaptine A in Asparagus officinalis. Nakabayashi R, Hashimoto K et al. Plant Biotechnol (Tokyo) 2021;38(3):311-315
A new technological approach in diagnostic pathology: mass spectrometry imaging-based metabolomics for biomarker detection in urachal cancer. Neumann JM, Niehaus K et al. Lab Invest 2021;101:1281-1288
A new technological approach in diagnostic pathology: mass spectrometry imaging-based metabolomics for biomarker detection in urachal cancer. Neumann JM, Niehaus K et al. Lab Invest 2021;101(9):1281-1288
Mass spectrometry-based protein identification in proteomics-a review. Noor Z, Ahn SB et al. Brief Bioinform 2021;22(2):1620-1638
Tryptophan metabolism is inversely regulated in the tumor and blood of patients with glioblastoma. Panitz V, Končarević S et al. Theranostics 2021;11(19):9217-9233
MALDI-IMS as a Tool to Determine the Myocardial Response to Syndecan-2-Selected Mesenchymal Stromal Cell Application in an Experimental Model of Diabetic Cardiomyopathy. Pappritz K, Klein O et al. Proteomics Clin Appl 2021;15(1):e2000050
Fast Nanoliter-Scale Cell Assays Using Droplet Microarray-Mass Spectrometry Imaging. RamalloGuevara C, Paulssen D et al. Adv Biol (Weinh) 2021;5(3):e2000279
Mineralization of 3D Osteogenic Model Based on Gelatin-Dextran Hybrid Hydrogel Scaffold Bioengineered with Mesenchymal Stromal Cells: A Multiparametric Evaluation. Re F, Sartore L et al. Materials (Basel) 2021;14(14)
Complete spatial characterisation of N-glycosylation upon striatal neuroinflammation in the rodent brain. Rebelo AL, Gubinelli F et al. J Neuroinflammation 2021;18(1):116
Safety, Tissue Distribution, and Metabolism of LNA-Containing Antisense Oligonucleotides in Rats. Romero-Palomo F, Festag M et al. Toxicol Pathol 2021;49:1174-1192
Defining the Tumor Microenvironment by Integration of Immunohistochemistry and Extracellular Matrix Targeted Imaging Mass Spectrometry. Rujchanarong D, Lefler J et al. Cancers (Basel) 2021;13(17)
Clinical importance of high-mannose, fucosylated, and complex N-glycans in breast cancer metastasis. Ščupáková K, Adelaja OT et al. JCI Insight 2021;6(24)
CRL4AMBRA1 is a master regulator of D-type cyclins. Simoneschi D, Rona G et al. Nature 2021;592(7856):789-793
Elaboration Pipeline for the Management of MALDI-MS Imaging Datasets. Smith A, Piga I et al. Methods Mol Biol 2021;2361:129-142
Traumatic brain injury induces region-specific glutamate metabolism changes as measured by multiple mass spectrometry methods. Sowers JL, Sowers ML et al. iScience 2021;24(10):103108
Inhibition of Ganglioside Synthesis Suppressed Liver Cancer Cell Proliferation through Targeting Kinetochore Metaphase Signaling. Su T, Qin XY et al. Metabolites 2021;11(3)
Visualizing the distributions and spatiotemporal changes of metabolites in Panax notoginseng by MALDI mass spectrometry imaging. Sun C, Ma S et al. J Ginseng Res 2021;45(6):726-733
Integration of Mass Spectrometry Imaging and Machine Learning Visualizes Region-Specific Age-Induced and Drug-Target Metabolic Perturbations in the Brain. Vallianatou T, Shariatgorji R et al. ACS Chem Neurosci 2021;12(10):1811-1823
Rapid Automated Annotation and Analysis of N-Glycan Mass Spectrometry Imaging Data Sets Using NGlycDB in METASPACE. Veličković D, Bečejac T et al. Anal Chem 2021;93(40):13421-13425
Activation of the integrated stress response confers vulnerability to mitoribosome-targeting antibiotics in melanoma. Vendramin R, Katopodi V et al. J Exp Med 2021;218(9)
Experimental and Data Analysis Considerations for Three-Dimensional Mass Spectrometry Imaging in Biomedical Research. Vos DRN, Ellis SR et al. Mol Imaging Biol 2021;23:149-159
On-Slide Heat Sterilization Enables Mass Spectrometry Imaging of Tissue Infected with High-Threat Pathogens Outside of Biocontainment: A Study Directed at Mycobacterium tuberculosis. Wang N, Sarathy JP et al. J Am Soc Mass Spectrom 2021;32(11):2664-2674
Spatial-resolved metabolomics reveals tissue-specific metabolic reprogramming in diabetic nephropathy by using mass spectrometry imaging. Wang Z, Fu W et al. Acta Pharm Sin B 2021;11(11):3665-3677
Clostridioides difficile infection induces a rapid influx of bile acids into the gut during colonization of the host. Wexler AG, Guiberson ER et al. Cell Rep 2021;36(10):109683
Trophoblast Cell Surface Antigen 2 (Trop-2) Protein is Highly Expressed in Salivary Gland Carcinomas and Represents a Potential Therapeutic Target. Wolber P, Nachtsheim L et al. Head Neck Pathol 2021;15:1147-1155
Icaritin Provides Neuroprotection in Parkinson's Disease by Attenuating Neuroinflammation, Oxidative Stress, and Energy Deficiency. Wu H, Liu X et al. Antioxidants (Basel) 2021;10(4)
Discovery of Spatial Peptide Signatures for Neuroblastoma Risk Assessment by MALDI Mass Spectrometry Imaging. Wu Z, Hundsdoerfer P et al. Cancers (Basel) 2021;13(13)
Lipidomic Analysis Reveals the Protection Mechanism of GLP-1 Analogue Dulaglutide on High-Fat Diet-Induced Chronic Kidney Disease in Mice. Yeung MHY, Leung KL et al. Front Pharmacol 2021;12:777395
Integration of omics analysis and atmospheric pressure MALDI mass spectrometry imaging reveals the cadmium toxicity on female ICR mouse. Zeng T, Guo W et al. Sci Total Environ 2021;801:149803
Airborne fine particulate matter induces cognitive and emotional disorders in offspring mice exposed during pregnancy. Zhao C, Xie P et al. Sci Bull (Beijing) 2021;66(6):578-591
A Small Molecule Coordinates Symbiotic Behaviors in a Host Organ. Zink KE, Ludvik DA et al. mBio 2021;12(2)
MALDI mass Spectrometry based proteomics for drug discovery & development. Zubair F Drug Discov Today Technol 2021;40:29-35

SCiLS Lab Bibliography 2020

Title Author Publication Link
Simultaneous Detection of Zinc and Its Pathway Metabolites Using MALDI MS Imaging of Prostate Tissue. Andersen MK, Krossa S et al. Anal Chem 2020;92:3171-3179
In situ metabolite and lipid analysis of GluN2D-/- and wild-type mice after ischemic stroke using MALDI MSI. Andrews WT, Donahue D et al. Anal Bioanal Chem 2020;412(24):6275-6285
Extracellular matrix alterations in low-grade lung adenocarcinoma compared with normal lung tissue by imaging mass spectrometry. Angel PM, Bruner E et al. J Mass Spectrom 2020;55:e4450
Zonal regulation of collagen-type proteins and posttranslational modifications in prostatic benign and cancer tissues by imaging mass spectrometry. Angel PM, Spruill L et al. Prostate 2020;80(13):1071-1086
Imaging Study by Mass Spectrometry of the Spatial Variation of Cellulose and Hemicellulose Structures in Corn Stalks. Arnaud B, Durand S et al. J Agric Food Chem 2020;68(13):4042-4050
MALDI-TOF Mass Spectrometry Revealed Significant Lipid Variations in Follicular Fluid and Somatic Follicular Cells but Not in Enclosed Oocytes between the Large Dominant and Small Subordinate Follicles in Bovine Ovary. Bertevello PS, Teixeira-Gomes AP et al. Int J Mol Sci 2020;21(18)
µ Opioid Receptor Agonism for L-DOPA-Induced Dyskinesia in Parkinson's Disease. Bezard E, Li Q et al. J Neurosci 2020;40(35):6812-6819
Visualizing Microbial Community Dynamics via a Controllable Soil Environment. Bhattacharjee A, Velickovic D et al. mSystems 2020;5(1)
Detection of small molecule concentration gradients in ocular tissues and humours. Boughton BA, Thomas ORB et al. J Mass Spectrom 2020;55:e4460
N-glycomic signature of stage II colorectal cancer and its association with the tumor microenvironment. Boyaval F, Van Zeijl R et al. Mol Cell Proteomics 2020
Welding fume inhalation exposure and high-fat diet change lipid homeostasis in rat liver. Boyce GR, Shoeb M et al. Toxicol Rep 2020;7:1350-1355
A Simple and Effective Sample Preparation Strategy for MALDI-MS Imaging of Neuropeptide Changes in the Crustacean Brain Due to Hypoxia and Hypercapnia Stress. Buchberger AR, Vu NQ et al. J Am Soc Mass Spectrom 2020;31(5):1058-1065
MALDI-MSI spatially maps N-glycan alterations to histologically distinct pulmonary pathologies following irradiation. Carter CL, Parker GA et al. Sci Rep 2020;10(1):11559
Antigen Retrieval and Its Effect on the MALDI-MSI of Lipids in Formalin-Fixed Paraffin-Embedded Tissue. Denti V, Piga I et al. J Am Soc Mass Spectrom 2020;31:1619-1624
MS Imaging-Guided Microproteomics for Spatial Omics on a Single Instrument. Dewez F, Oejten J et al. Proteomics 2020;20:e1900369
MALDI MSI Reveals the Spatial Distribution of Protein Markers in Tracheobronchial Lymph Nodes and Lung of Pigs after Respiratory Infection. Do T, Guran R et al. Molecules 2020;25(23)
Defining the human kidney N-glycome in normal and cancer tissues using MALDI imaging mass spectrometry. Drake RR, McDowell C et al. J Mass Spectrom 2020;55:e4490
Validation of MALDI-MS imaging data of selected membrane lipids in murine brain with and without laser postionization by quantitative nano-HPLC-MS using laser microdissection. Eiersbrock FB ,Orthen JM ,Soltwisch J Anal Bioanal Chem 2020;412(25):6875-6886
Spatial metabolomics of in situ host-microbe interactions at the micrometre scale. Geier B, Sogin EM et al. Nat Microbiol 2020;5(3):498-510
Revealing the Regional Localization and Differential Lung Retention of Inhaled Compounds by Mass Spectrometry Imaging. Hamm GR, Bäckström E et al. J Aerosol Med Pulm Drug Deliv 2020;33:43-53
MALDI-2 for the Enhanced Analysis of N-Linked Glycans by Mass Spectrometry Imaging. Heijs B, Potthoff A et al. Anal Chem 2020;92(20):13904-13911
Simultaneous mass spectrometry imaging of multiple neuropeptides in the brain and alterations induced by experimental parkinsonism and L-DOPA therapy. Hulme H, Fridjonsdottir E et al. Neurobiol Dis 2020;137:104738
Sample preparation strategies for high-throughput mass spectrometry imaging of primary tumor organoids. Johnson J, Sharick JT et al. J Mass Spectrom 2020;55:e4452
Glioblastoma multiforme: Metabolic differences to peritumoral tissue and IDH-mutated gliomas revealed by mass spectrometry imaging. Kampa JM, Kellner U et al. Neuropathology 2020;40(6):546-558
Mass spectrometry imaging reveals lipid upregulation and bile acid changes indicating amitriptyline induced steatosis in a rat model. Kampa JM, Sahin M et al. Toxicol Lett 2020;325:43-50
Multiplex enzyme activity imaging by MALDI-IMS of substrate library conversions. Klein O, Haeckel A et al. Sci Rep 2020;10(1):15522
Comparison of Dietary Oils with Different Polyunsaturated Fatty Acid n-3 and n-6 Content in the Rat Model of Cutaneous Wound Healing. Komprda T, Sladek Z et al. Int J Mol Sci 2020;21(21)
Discovery of Prognostic Markers for Early-Stage High-Grade Serous Ovarian Cancer by Maldi-Imaging. Kulbe H, Klein O et al. Cancers (Basel) 2020;12(8)
Derangements of amino acids in cachectic skeletal muscle are caused by mitochondrial dysfunction. Kunzke T, Buck A et al. J Cachexia Sarcopenia Muscle 2020;11(1):226-240
Hepatotoxic effects of inhalation exposure to polycyclic aromatic hydrocarbons on lipid metabolism of C57BL/6 mice. Li F, Xiang B et al. Environ Int 2020;134:105000
Peak detection for MALDI mass spectrometry imaging data using sparse frame multipliers. Lieb F ,Boskamp T ,Stark HG J Proteomics 2020;225:103852
Storage Conditions of Human Kidney Tissue Sections Affect Spatial Lipidomics Analysis Reproducibility. Lukowski JK, Pamreddy A et al. J Am Soc Mass Spectrom 2020;31:2538-2546
Evaluation of Data Analysis Platforms and Compatibility with MALDI-TOF Imaging Mass Spectrometry Data Sets. Luu GT, Condren AR et al. J Am Soc Mass Spectrom 2020;31(6):1313-1320
Imaging Mass Spectrometry and Lectin Analysis of N-linked Glycans in Carbohydrate Antigen Defined Pancreatic Cancer Tissues. McDowell CT, Klamer Z et al. Mol Cell Proteomics 2020
Chemical imaging of evolving amyloid plaque pathology and associated Aβ peptide aggregation in a transgenic mouse model of Alzheimer's disease. Michno W, Wehrli P et al. J Neurochem 2020;152:602-616
Lipid signature of advanced human carotid atherosclerosis assessed by mass spectrometry imaging. Moerman AM, Visscher M et al. J Lipid Res 2020
A Co-registration Pipeline for Multimodal MALDI and Confocal Imaging Analysis of Stem Cell Colonies. Nikitina A, Huang D et al. J Am Soc Mass Spectrom 2020;31(4):986-989
Localized Metabolomic Gradients in Patient-Derived Xenograft Models of Glioblastoma. Randall EC, Lopez BGC et al. Cancer Res 2020;80:1258-1267
Unique and highly specific cyanogenic glycoside localization in stigmatic cells and pollen in the genus Lomatia (Proteaceae). Ritmejerytė E, Boughton BA et al. Ann Bot 2020;126(3):387-400
Dual Mass Spectrometric Tissue Imaging of Nanocarrier Distributions and Their Biochemical Effects. Sikora KN, Hardie JM et al. Anal Chem 2020;92:2011-2018
Detecting Proteomic Indicators to Distinguish Diabetic Nephropathy from Hypertensive Nephrosclerosis by Integrating Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging with High-Mass Accuracy Mass Spectrometry. Smith A, Iablokov V et al. Kidney Blood Press Res 2020;45(2):233-248
On-Tissue Derivatization Strategy for Mass Spectrometry Imaging of Carboxyl-Containing Metabolites in Biological Tissues. Sun C, Liu W et al. Anal Chem 2020;92(18):12126-12131
Development of a high-coverage matrix-assisted laser desorption/ionization mass spectrometry imaging method for visualizing the spatial dynamics of functional metabolites in Salvia miltiorrhiza Bge. Sun C, Liu W et al. J Chromatogr A 2020;1614:460704
1,1'-binaphthyl-2,2'-diamine as a novel MALDI matrix to enhance the in situ imaging of metabolic heterogeneity in lung cancer. Sun C, Liu W et al. Talanta 2020;209:120557
The choice of tissue fixative is a key determinant for mass spectrometry imaging based tumor metabolic reprogramming characterization. Sun C, Wang F et al. Anal Bioanal Chem 2020;412(13):3123-3134
A spatially-resolved approach to visualize the distribution and biosynthesis of flavones in Scutellaria baicalensis Georgi. Sun C, Zhang M et al. J Pharm Biomed Anal 2020;179:113014
Mass Spectrometry Imaging Establishes 2 Distinct Metabolic Phenotypes of Aldosterone-Producing Cell Clusters in Primary Aldosteronism. Sun N, Meyer LS et al. Hypertension 2020;75:634-644
Effects of Thymoquinone on Small-Molecule Metabolites in a Rat Model of Cerebral Ischemia Reperfusion Injury Assessed using MALDI-MSI. Tian F, Liu R et al. Metabolites 2020;10(1)
Considerations for MALDI-Based Quantitative Mass Spectrometry Imaging Studies. Tobias F ,Hummon AB J Proteome Res 2020;19(9):3620-3630
Sample Preparation for Metabolic Profiling using MALDI Mass Spectrometry Imaging. Veerasammy K, Chen YX et al. J Vis Exp 2020
Response Surface Methodology As a New Approach for Finding Optimal MALDI Matrix Spraying Parameters for Mass Spectrometry Imaging. Veličković D, Zhang G et al. J Am Soc Mass Spectrom 2020;31(3):508-516
Investigation of Xenobiotics Metabolism In Salix alba Leaves via Mass Spectrometry Imaging. Villette C ,Maurer L ,Heintz D J Vis Exp 2020
Localization of the lens intermediate filament switch by imaging mass spectrometry. Wang Z ,Ryan DJ ,Schey KL Exp Eye Res 2020;198:108134
Opisthobranch grazing results in mobilisation of spherulous cells and re-allocation of secondary metabolites in the sponge Aplysina aerophoba. Wu YC, García-Altares M et al. Sci Rep 2020;10(1):21934
Spatial Lipidomics Reveals Anticancer Mechanisms of Bufalin in Combination with Cinobufagin in Tumor-Bearing Mice. Zhang J, Hong Y et al. Front Pharmacol 2020;11:593815
Evaluation of the splenic injury following exposure of mice to bisphenol S: A mass spectrometry-based lipidomics and imaging analysis. Zhao C, Yong T et al. Environ Int 2020;135:105378

SCiLS Lab Bibliography 2019

Title Author Publication Link
Extracellular Matrix Alterations in Low Grade Lung Adenocarcinoma Compared to Normal Lung Tissue by Imaging Mass Spectrometry Angel PM, Bruner E et al. Journal of Mass Spectrometry. 2019
Extracellular Matrix Imaging of Breast Tissue Pathologies by MALDI–Imaging Mass Spectrometry Angel PM, Schwamborn K et al. PROTEOMICS–Clinical Applications. 2019;13(1):1700152
Neratinib protects pancreatic beta cells in diabetes Ardestani A, Li S et al. Nature communications. 2019;10(1):1-17
Integrative Clustering in Mass Spectrometry Imaging for Enhanced Patient Stratification Balluff B, Buck A et al. PROTEOMICS–Clinical Applications. 2019;13(1):1800137
Dual strategy for reduced signal-suppression effects in matrix-assisted laser desorption/ionization mass spectrometry imaging Bastrup J, Birkelund S et al. Rapid Communications in Mass Spectrometry. 2019;33(22):1711-21
Metal Oxide Laser Ionization Mass Spectrometry Imaging (MOLI MSI) Using Cerium (IV) Oxide Basu SS, McMinn MH et al. Analytical chemistry. 2019;91(10):6800-7
Rapid MALDI mass spectrometry imaging for surgical pathology Basu SS, Regan MS et al. NPJ precision oncology. 2019;3(1):1-5
MALDI Mass Spectrometry Imaging Linked with Top-Down Proteomics as a Tool to Study the Non-Small-Cell Lung Cancer Tumor Microenvironment Berghmans E, Van Raemdonck G et al. Methods and protocols. 2019;2(2):44
Antibody Panel Based N-Glycan Imaging for N-Glycoprotein Biomarker Discovery Black AP, Angel PM et al. Current protocols in protein science. 2019;98(1):e99
A novel mass spectrometry platform for multiplexed N-Glycoprotein biomarker discovery from patient biofluids by antibody panel based N-Glycan imaging Black AP, Liang H et al. Analytical chemistry. 2019;91(13):8429-35
Using the chemical noise background in MALDI mass spectrometry imaging for mass alignment and calibration Boskamp T, Lachmund D et al. Analytical Chemistry. 2019
Detection of small molecule concentration gradients in ocular tissues and humours Boughton BA, Thomas OR et al. Journal of Mass Spectrometry. 2019
MALDI Mass Spectrometry Imaging of Early- and Late-Stage Serous Ovarian Cancer Tissue Reveals Stage-Specific N-Glycans Briggs MT, Condina MR et al. Proteomics. 2019;19(21-22):1800482
Translating N-glycan analytical applications into clinical strategies for ovarian cancer Briggs MT, Condina MR et al. PROTEOMICS–Clinical Applications. 2019;13(3):1800099
Mass spectrometry-based integration and expansion of the chemical diversity harbored within a marine sponge Cantrell TP, Freeman CJ et al. Journal of The American Society for Mass Spectrometry. 2019;30(8):1373-84
Development of a class prediction model to discriminate pancreatic ductal adenocarcinoma from pancreatic neuroendocrine tumor by MALDI mass spectrometry imaging Casadonte R, Kriegsmann M et al. PROTEOMICS–Clinical Applications. 2019;13(1):1800046
Biofilm inhibitor taurolithocholic acid alters colony morphology, specialized metabolism, and virulence of Pseudomonas aeruginosa Condren AR, Kahl LJ et al. ACS Infectious Diseases. 2019
Targeted feature extraction in MALDI mass spectrometry imaging to discriminate proteomic profiles of breast and ovarian cancer Cordero Hernandez Y, Boskamp T et al. PROTEOMICS–Clinical Applications. 2019;13(1):1700168
Assessing the effect of nitisinone induced hypertyrosinaemia on monoamine neurotransmitters in brain tissue from a murine model of alkaptonuria using mass spectrometry imaging Davison AS, Strittmatter N et al. Metabolomics. 2019;15(5):68
Age-related spatial differences of human lens UV filters revealed by negative ion mode MALDI imaging mass spectrometry Demarais NJ, Donaldson PJ, Grey AC Experimental eye research. 2019;184:146-51
Defining the Human Kidney N-Glycome in Normal and Cancer Tissues Using MALDI Imaging Mass Spectrometry Drake RR, McDowell C et al. Journal of Mass Spectrometry. 2019:e4490
Spatially resolved endogenous improved metabolite detection in human osteoarthritis cartilage by matrix assisted laser desorption ionization mass spectrometry imaging Eveque-Mourroux M, Emans P et al. Analyst. 2019;144(20):5953-8
Pre-and Postoperative Neratinib for HER2-Positive Breast Cancer Brain Metastases: Translational Breast Cancer Research Consortium 022 Freedman RA, Gelman RS et al. Clinical breast cancer. 2019
Spatial UBE2N protein expression indicates genomic instability in colorectal cancers Gemoll T, Miroll E et al. BMC cancer. 2019;19(1):710
MALDI-Mass Spectrometry Imaging to Investigate Lipid and Bile Acid Modifications Caused by Lentil Extract Used as a Potential Hypocholesterolemic Treatment Genangeli M, Heijens AM et al. Journal of the American Society for Mass Spectrometry. 2019;30(10):2041-50
Spatio-Temporal Metabolite and Elemental Profiling of Salt Stressed Barley Seeds During Initial Stages of Germination by MALDI-MSI and μ-XRF Spectrometry Gupta SVK, Rupasinghe TWT et al. Frontiers in plant science. 2019;10:1139
Revealing the Regional Localization and Differential Lung Retention of Inhaled Compounds by Mass Spectrometry Imaging Hamm GR, Bäckström E et al. Journal of aerosol medicine and pulmonary drug delivery. 2019
Polydopamine-capped AgNPs as a novel matrix overcoming the ion suppression of phosphatidylcholine for MALDI MS comprehensive imaging of glycerophospholipids and sphingolipids in impact-induced injured brain Han C, Li S et al. Analyst. 2019;144(21):6304-12
MALDI Imaging Mass Spectrometry: Neurochemical Imaging of Proteins and Peptides Hanrieder J, Zetterberg H, Blennow K. Neuroproteomics: Springer; 2019. p. 179-97
Identification of Proteomic Markers in Head and Neck Cancer Using MALDI–MS Imaging, LC–MS/MS, and Immunohistochemistry Hoffmann F, Umbreit C et al. PROTEOMICS – Clinical Applications. 2019;13(1):1700173. doi: 10.1002/prca.201700173
Matrix-assisted laser desorption/ionization mass spectrometry imaging to uncover protein alterations associated with the progression of IgA nephropathy Ivanova M, Dyadyk O et al. Virchows Archiv. 2019:1-12
Sample Preparation Strategies for High-Throughput Mass Spectrometry Imaging of Primary Tumor Organoids Johnson J, Sharick JT et al. Journal of Mass Spectrometry. 2019
MALDI-Imaging for Classification of Epithelial Ovarian Cancer Histotypes from a Tissue Microarray Using Machine Learning Methods Klein O, Kanter F et al. PROTEOMICS–Clinical Applications. 2019;13(1):1700181
The Emerging Role of Cytoskeletal Proteins as Reliable Biomarkers Klingler-Hoffmann M, Mittal P, Hoffmann P Proteomics. 2019;19(21-22):1800483
Mapping natural dyes in archeological textiles by imaging mass spectrometry Kramell AE, García-Altares M et al. Scientific reports. 2019;9(1):1-9
MALDI imaging for proteomic painting of heterogeneous tissue structures Kriegsmann J, Kriegsmann M et al. PROTEOMICS–Clinical Applications. 2019;13(1):1800045
Combined Immunohistochemistry after Mass Spectrometry Imaging for superior spatial information Kriegsmann K, Longuespée R et al. PROTEOMICS–Clinical Applications. 2019;13(1):1800035
Derangements of amino acids in cachectic skeletal muscle are caused by mitochondrial dysfunction Kunzke T, Buck A et al. Journal of Cachexia, Sarcopenia and Muscle. 2019
MALDI imaging in Fabry nephropathy: a multicenter study L’Imperio V, Smith A et al. Journal of nephrology. 2019:1-8
Histopathology-guided mass spectrometry differentiates benign nevi from malignant melanoma Lazova R, Smoot K et al. Journal of cutaneous pathology. 2019
MALDI–MSI Pilot Study Highlights Glomerular Deposits of Macrophage Migration Inhibitory Factor as a Possible Indicator of Response to Therapy in Membranous Nephropathy L’Imperio V, Smith A et al. PROTEOMICS–Clinical Applications. 2019;13(3):1800019
Metabolomics profiling of methamphetamine addicted human serum and three rat brain areas Lin M, Xu J et al. RSC Advances. 2019;9(70):41107-19
Effect of Shenfu injection on lipopolysaccharide (LPS)-induced septic shock in rabbits Liu X, Liu R et al. Journal of ethnopharmacology. 2019;234:36-43
In MALDI–Mass Spectrometry Imaging on Formalin-Fixed Paraffin-Embedded Tissue Specimen Section Thickness Significantly Influences m/z Peak Intensity Longuespée R, Kriegsmann K et al. PROTEOMICS–Clinical Applications. 2019;13(1):1800074
Site-to-Site Reproducibility and Spatial Resolution in MALDI–MSI of Peptides from Formalin-Fixed Paraffin-Embedded Samples Ly A, Longuespée R et al. PROTEOMICS–Clinical Applications. 2019;13(1):1800029
Enhanced Coverage of Insect Neuropeptides in Tissue Sections by an Optimized Mass-Spectrometry-Imaging Protocol Ly A, Ragionieri L et al. Analytical chemistry. 2019;91(3):1980-8
Maldi msi of lipids in experimental model of traumatic brain injury detects acylcarnitines as injury related markers lah K, Quanico J et al. 2019
Distinguishing core from penumbra by lipid profiles using Mass Spectrometry Imaging in a transgenic mouse model of ischemic stroke Mulder I, Potočnik NO et al. Scientific reports. 2019;9(1):1-10
Intratumoral immunotherapy with TLR7/8 agonist MEDI9197 modulates the tumor microenvironment leading to enhanced activity when combined with other immunotherapies Mullins SR, Vasilakos JP et al. Journal for immunotherapy of cancer. 2019;7(1):1-18
Evaluation of Small Molecule Drug Uptake in patient-Derived prostate cancer explants by Mass Spectrometry Mutuku SM, Trim PJ et al. Scientific reports. 2019;9(1):1-11
Keeping the shape of plant tissue for visualizing metabolite features in segmentation and correlation analysis of imaging mass spectrometry in Asparagus officinalis Nakabayashi R, Hashimoto K et al. Metabolomics. 2019;15(2):24
Unsupervised machine learning using an imaging mass spectrometry dataset automatically reassembles grey and white matter Nampei M, Horikawa M et al. Scientific reports. 2019;9(1):1-11
MALDI-imaging mass spectrometry screening of lipid profile changes in the rat model for tauopathies Olesova D, Majerova P, Kovac A 4th Meeting of Middle European Societies for Immunology and Allergology; 2019: Wiley Online Library
Higher mass accuracy MALDI-TOF/TOF lipid imaging of human brain tissue in Alzheimer’s disease O’Rourke MB, Smith CC et al. Current protocols in molecular biology. 2019;126(1):e86
‘What did I do wrong?’ An empirical evaluation of sample preparation methodologies in matrix-assisted laser desorption/ionization-mass spectrometry imaging O’Rourke MB, Smith CC et al. Future Science OA. 2019;5(4):FSO362
Three-dimensional mass spectrometry imaging identifies lipid markers of medulloblastoma metastasis Paine MR, Liu J et al. Scientific reports. 2019;9(1):1-10
Lipidomic changes in the rat hippocampus following cocaine conditioning, extinction, and reinstatement of drug-seeking Pati S, Angel P et al. Brain and behavior. 2019;9(12):e01451
Uncovering Matrix Effects on Lipid Analyses in MALDI Imaging Mass Spectrometry Experiments Perry WJ, Patterson NH et al. Journal of Mass Spectrometry. 2019:e4491
Novel prognostic markers in triple-negative breast cancer discovered by MALDI-mass spectrometry imaging Phillips L, Gill AJ, Baxter RC Frontiers in oncology. 2019;9:379
Molecular characterization of prostate cancer with associated Gleason score using mass spectrometry imaging Randall EC, Zadra G et al. Molecular Cancer Research. 2019;17(5):1155-65
Mapping insoluble indole metabolites in the gastrointestinal environment of a murine colorectal cancer model using desorption/ionisation on porous silicon imaging Rudd DA, Benkendorff K et al. Scientific reports. 2019;9(1):1-13
Comparative spatial lipidomics analysis reveals cellular lipid remodelling in different developmental zones of barley roots in response to salinity Sarabia LD, Boughton BA et al. Plant, cell & environment. 2019
In plaque-mass spectrometry imaging of a bloom-forming alga during viral infection reveals a metabolic shift towards odd-chain fatty acid lipids Schleyer G, Shahaf N et al. Nature microbiology. 2019;4(3):527-38
Maintenance of Deep Lung Architecture and Automated Airway Segmentation for 3D Mass Spectrometry Imaging Scott AJ, Chandler CE et al. Scientific Reports. 2019;9(1):1-12
Microscopy and Mass Spectrometry Imaging Reveals the Distributions of Curcumin Species in Dried Turmeric Root Shimma S, Sagawa T Journal of Agricultural and Food Chemistry. 2019;67(34):9652-7. doi: 10.1021/acs.jafc.9b02768
Molecular signatures of medullary thyroid carcinoma by matrix-assisted laser desorption/ionisation mass spectrometry imaging Smith A, Galli M et al. Journal of proteomics. 2019;191:114-23
High Spatial Resolution MALDI-MS Imaging in the Study of Membranous Nephropathy Smith A, L’Imperio V et al. PROTEOMICS–Clinical Applications. 2019;13(1):1800016
High-Performance Molecular Imaging with MALDI Trapped Ion-Mobility Time-of-Flight (timsTOF) Mass Spectrometry Spraggins JM, Djambazova KV et al. Analytical chemistry. 2019;91(22):14552-60
Ambient metabolic profiling and imaging of biological samples with ultrahigh molecular resolution using laser ablation electrospray ionization 21 tesla FTICR mass spectrometry Stopka SA, Samarah LZ et al. Analytical chemistry. 2019;91(8):5028-35
Sarcosine is a prostate epigenetic modifier that elicits aberrant methylation patterns through the SAM e-Dnmts axis Strmiska V, Michalek P et al. Molecular oncology. 2019;13(5):1002-17
The use of 1, 5-diaminonaphthalene for matrix-assisted laser desorption/ionization mass spectrometry imaging of brain in neurodegenerative disorders Strnad Š, Pražienková V et al. Talanta. 2019;201:364-72
Acetone immersion enhanced MALDI-MS imaging of small molecule metabolites in biological tissues Sun C, Li Z et al. Journal of pharmaceutical and biomedical analysis. 2019;176:112797
A process of convergent amplification and tissue-specific expression dominates the evolution of toxin and toxin-like genes in sea anemones Surm JM, Smith HL et al. Molecular ecology. 2019;28(9):2272-89
Quantitative MALDI imaging of spatial distributions and dynamic changes of tetrandrine in multiple organs of rats Tang W, Chen J et al. Theranostics. 2019;9(4):932
Deciphering PSE-like muscle defect in cooked hams: A signature from the tissue to the molecular scale Théron L, Sayd T et al. Food chemistry. 2019;270:359-66
Developing a Drug Screening Platform: MALDI-Mass Spectrometry Imaging of Paper-Based Cultures Tobias F, McIntosh JC et al. Analytical chemistry. 2019;91(24):15370-6
Peptide Profile Differences of Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features, Encapsulated Follicular Variant, and Classical Papillary Thyroid Carcinoma: An Application of Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging Ucal Y, Tokat F et al. Thyroid. 2019;29(8):1125-37
Molecular imaging identifies age-related attenuation of acetylcholine in retrosplenial cortex in response to acetylcholinesterase inhibition Vallianatou T, Shariatgorji M et al. Neuropsychopharmacology. 2019;44(12):2091-8
Rapid Identification of Ischemic Injury in Renal Tissue by Mass-Spectrometry Imaging van Smaalen T, Ellis S et al. Analytical chemistry. 2019;91(5):3575-81
Mass spectrometric imaging of cysteine rich proteins in human skin Vanickova L, Guran R et al. International journal of biological macromolecules. 2019;125:270-7
An approach for visualizing the spatial metabolome of an entire plant root system inspired by the Swiss-rolling technique Veličković D, Chu RK et al. Journal of Mass Spectrometry. 2019
Spatiotemporal Transformation in the Alkaloid Profile of Pinus Roots in Response to Mycorrhization Veličković D, Liao H-L et al. Journal of natural products. 2019;82(5):1382-6
In situ localization of micropollutants and associated stress response in Populus nigra leaves Villette C, Maurer L et al. Environment international. 2019;126:523-32
Strategies for managing multi-patient 3D mass spectrometry imaging data Vos D, Jansen I et al. Journal of proteomics. 2019;193:184-91
Software solutions for evaluation and visualization of laser ablation inductively coupled plasma mass spectrometry imaging (LA-ICP-MSI) data: a short overview Weiskirchen R, Weiskirchen S et al. Journal of cheminformatics. 2019;11(1):16
Pharmacodynamic Evaluation of Shenfu Injection in Rats With Ischemic Heart Failure and Its Effect on Small Molecules Using Matrix-Assisted Laser Desorption/Ionization–Mass Spectrometry Imaging Wu H, Dai Z et al. Frontiers in Pharmacology. 2019;10(1424). doi: 10.3389/fphar.2019.01424


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