Title | Author | Publication | Link |
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Impact of spatial metabolomics on immune-microenvironment in oral cancer prognosis: a clinical report. | Bag S, Oetjen J et al. | Mol Cell Biochem 2023 | https://doi.org/10.1007/s11010-023-04713-3 |
Spatial resolution of renal amyloid deposits through MALDI-MSI: a combined digital and molecular approach to monoclonal gammopathies. | Bindi G, Smith A et al. | J Clin Pathol 2023 | https://doi.org/10.1136/jcp-2023-208790 |
Rewiring of the N-Glycome with prostate cancer progression and therapy resistance. | Butler W, McDowell C et al. | NPJ Precis Oncol 2023;7(1):22 | https://doi.org/10.1038/s41698-023-00363-2 |
3D bioprinted colorectal cancer models based on hyaluronic acid and signalling glycans. | Cadamuro F, Marongiu L et al. | Carbohydr Polym 2023;302:120395 | https://doi.org/10.1016/j.carbpol.2022.120395 |
A Comparison of Different Sample Processing Protocols for MALDI Imaging Mass Spectrometry Analysis of Formalin-Fixed Multiple Myeloma Cells. | Casadonte R, Kriegsmann J et al. | Cancers (Basel) 2023;15(3) | https://doi.org/10.3390/cancers15030974 |
Imaging Mass Spectrometry for the Classification of Melanoma Based on BRAF/NRAS Mutational Status. | Casadonte R, Kriegsmann M et al. | Int J Mol Sci 2023;24(6) | https://doi.org/10.3390/ijms24065110 |
MALDI-IHC-Guided In-Depth Spatial Proteomics: Targeted and Untargeted MSI Combined. | Claes BSR, Krestensen KK et al. | Anal Chem 2023;95(4):2329-2338 | https://doi.org/10.1021/acs.analchem.2c04220 |
In Situ Imaging of O-Linked β-N-Acetylglucosamine Using On-Tissue Hydrolysis and MALDI Mass Spectrometry. | Escobar EE, Seeley EH et al. | Cancers (Basel) 2023;15(4) | https://doi.org/10.3390/cancers15041224 |
Longitudinal spatial mapping of lipid metabolites reveals pre-symptomatic changes in the hippocampi of Huntington's disease transgenic mice. | Farzana F, McConville MJ et al. | Neurobiol Dis 2023;176:105933 | https://doi.org/10.1016/j.nbd.2022.105933 |
MALDI mass spectrometry imaging shows a gradual change in the proteome landscape during mouse ovarian folliculogenesis. | Fiorentino G, Smith A et al. | Mol Hum Reprod 2023;29(4) | https://doi.org/10.1093/molehr/gaad006 |
Titania Nanosheet as a Matrix for Surface-Assisted Laser Desorption/Ionization Mass Spectrometry Analysis and Imaging. | Gao C, Wang Y et al. | Anal Chem 2023;95(2):650-658 | https://doi.org/10.1021/acs.analchem.2c01878 |
MALDI Imaging, a Powerful Multiplex Approach to Decipher Intratumoral Heterogeneity: Combined Hepato-Cholangiocarcinomas as Proof of Concept. | Gigante E, Cazier H et al. | Cancers (Basel) 2023;15(7) | https://doi.org/10.3390/cancers15072143 |
Characterization of Hormone Receptor and HER2 Status in Breast Cancer Using Mass Spectrometry Imaging. | Gonçalves JPL, Bollwein C et al. | Int J Mol Sci 2023;24(3) | https://doi.org/10.3390/ijms24032860 |
Optimized protocol for MALDI MSI of N-glycans using an on-tissue digestion in fresh frozen tissue sections. | Grgic A ,Krestensen KK ,Heeren RMA | Sci Rep 2023;13(1):2776 | https://doi.org/10.1038/s41598-023-29560-6 |
Divide and Conquer: A Flexible Deep Learning Strategy for Exploring Metabolic Heterogeneity from Mass Spectrometry Imaging Data. | Guo L, Dong J et al. | Anal Chem 2023;95(3):1924-32 | https://doi.org/10.1021/acs.analchem.2c04045 |
Sample preparation for lipid analysis of intra-articular adipose tissue by using matrix-assisted laser desorption/ionization imaging. | Haartmans MJJ, Claes BSR et al. | Anal Biochem 2023;662:115018 | https://doi.org/10.1016/j.ab.2022.115018 |
Tumor ratio of unsaturated to saturated sulfatide species is associated with disease-free survival in intrahepatic cholangiocarcinoma. | Huizing L, Chen L et al. | Cell Oncol (Dordr) 2023 | https://doi.org/10.1007/s13402-022-00766-6 |
Investigation of Phospholipid Differences in Valproic Acid-Induced Autistic Mouse Model Brain Using Mass Spectrometry Imaging. | Jang HJ, Kwon KJ et al. | Metabolites 2023;13(2) | https://doi.org/10.3390/metabo13020178 |
Effect of Micro-Patterned Mucin on Quinolone and Rhamnolipid Profiles of Mucoid Pseudomonas aeruginosa under Antibiotic Stress. | Jia J, Parmar D et al. | ACS Infect Dis 2023;9(1):150-161 | https://doi.org/10.1021/acsinfecdis.2c00519 |
Classification of Pancreatic Ductal Adenocarcinoma Using MALDI Mass Spectrometry Imaging Combined with Neural Networks. | Kanter F, Lellmann J et al. | Cancers (Basel) 2023;15(3) | https://doi.org/10.3390/cancers15030686 |
In Situ Self-Assembled Formation of Nitrogen-Rich Ag@Ti3C2 Film for Sensitive Detection and Spatial Imaging of Pesticides with Laser Desorption/Ionization Mass Spectrometry (LDI-MS). | Li W, He Q et al. | ACS Appl Mater Interfaces 2023;15(14):18402-18413 | https://doi.org/10.1021/acsami.2c22347 |
Spatial metabolomics reveals skeletal myofiber subtypes. | Luo L, Ma W et al. | Sci Adv 2023;9(5):eadd0455 | https://doi.org/10.1126/sciadv.add0455 |
Applications and continued evolution of glycan imaging mass spectrometry. | McDowell CT, Lu X et al. | Mass Spectrom Rev 2023;42(2):674-705 | https://doi.org/10.1002/mas.21725 |
Targeting succinate metabolism to decrease brain injury upon mechanical thrombectomy treatment of ischemic stroke. | Mottahedin A, Prag HA et al. | Redox Biol 2023;59:102600 | https://doi.org/10.1016/j.redox.2023.102600 |
Lipidized PrRP Analog Exhibits Strong Anti-Obesity and Antidiabetic Properties in Old WKY Rats with Obesity and Glucose Intolerance. | Mráziková L, Hojná S et al. | Nutrients 2023;15(2) | https://doi.org/10.3390/nu15020280 |
Monoisotopic silver nanoparticles-based mass spectrometry imaging of human bladder cancer tissue: Biomarker discovery. | Ossoliński K, Ruman T et al. | Adv Med Sci 2023;68(1):38-45 | https://doi.org/10.1016/j.advms.2022.12.002 |
Spatially Resolved Molecular Approaches for the Characterisation of Non-Invasive Follicular Tumours with Papillary-like Features (NIFTPs). | Piga I, L'Imperio V et al. | Int J Mol Sci 2023;24(3) | https://doi.org/10.3390/ijms24032567 |
Fast and Reproducible Matrix Deposition for MALDI Mass Spectrometry Imaging with Improved Glass Sublimation Setup. | Shanmugaraj N, Rutten T et al. | J Am Soc Mass Spectrom 2023;34(3):513-517 | https://doi.org/10.1021/jasms.2c00301 |
Development of Spheroid-FPOP: An In-Cell Protein Footprinting Method for 3D Tumor Spheroids. | Shortt RL, Wang Y et al. | J Am Soc Mass Spectrom 2023;34(3):417-425 | https://doi.org/10.1021/jasms.2c00307 |
A multimodal pipeline using NMR spectroscopy and MALDI-TOF mass spectrometry imaging from the same tissue sample. | Tressler CM, Ayyappan V et al. | NMR Biomed 2023;36(4):e4770 | https://doi.org/10.1002/nbm.4770 |
Detection of early proteomic alterations in 5xFAD Alzheimer's disease neonatal mouse model via MALDI-MSI. | Uras I, Karayel-Basar M et al. | Alzheimers Dement 2023 | https://doi.org/10.1002/alz.13008 |
Hepatic glutamine synthetase controls N5-methylglutamine in homeostasis and cancer. | Villar VH, Allega MF et al. | Nat Chem Biol 2023;19(3):292-300 | https://doi.org/10.1038/s41589-022-01154-9 |
Commensal microbiome promotes hair follicle regeneration by inducing keratinocyte HIF-1α signaling and glutamine metabolism. | Wang G, Sweren E et al. | Sci Adv 2023;9(1):eabo7555 | https://doi.org/10.1126/sciadv.abo7555 |
Mobility-resolved broadband dissociation and parallel reaction monitoring for laser desorption/ionization-mass spectrometry - Tattoo pigment identification supported by trapped ion mobility spectrometry. | Wolf C, Behrens A et al. | Anal Chim Acta 2023;1242:340796 | https://doi.org/10.1016/j.aca.2023.340796 |
Region-resolved multi-omics of the mouse eye. | Xiang H, Zhang B et al. | Cell Rep 2023;42(2):112121 | https://doi.org/10.1016/j.celrep.2023.112121 |
Exposure to isocyanates predicts atopic dermatitis prevalence and disrupts therapeutic pathways in commensal bacteria. | Zeldin J, Chaudhary PP et al. | Sci Adv 2023;9(1):eade8898 | https://doi.org/10.1126/sciadv.ade8898 |
Tandemly duplicated CYP82Ds catalyze 14-hydroxylation in triptolide biosynthesis and precursor production in Saccharomyces cerevisiae. | Zhang Y, Gao J et al. | Nat Commun 2023;14(1):875 | https://doi.org/10.1038/s41467-023-36353-y |
Title | Author | Publication | Link |
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The fatal trajectory of pulmonary COVID-19 is driven by lobular ischemia and fibrotic remodelling. | Ackermann M, Kamp JC et al. | EBioMedicine 2022;85:104296 | https://doi.org/10.1016/j.ebiom.2022.104296 |
A Protocol for the Acquisition of Comprehensive Proteomics Data from Single Cases Using Formalin-Fixed Paraffin Embedded Sections. | Acland M, Mittal P et al. | Methods Protoc 2022;5(4) | https://doi.org/10.3390/mps5040057 |
Venoms for all occasions: The functional toxin profiles of different anatomical regions in sea anemones are related to their ecological function. | Ashwood LM, Undheim EAB et al. | Mol Ecol 2022;31(3):866-883 | https://doi.org/10.1111/mec.16286 |
An overview of image registration for aligning mass spectrometry imaging with clinically relevant imaging modalities. | Balluff B ,Heeren RMA ,Race AM | J Mass Spectrom Adv Clin Lab 2022;23:26-38 | https://doi.org/10.1016/j.jmsacl.2021.12.006 |
Mass spectrometry-based metabolomics in microbiome investigations. | Bauermeister A, Mannochio-Russo H et al. | Nat Rev Microbiol 2022;20(3):143-160 | https://doi.org/10.1038/s41579-021-00621-9 |
Fallopian tube secreted protein affects ovarian metabolites in high grade serous ovarian cancer. | Bergsten TM, Levy SE et al. | Front Cell Dev Biol 2022;10:1042734 | https://doi.org/10.3389/fcell.2022.1042734 |
Mass spectrometry imaging to explore molecular heterogeneity in cell culture. | Bien T, Koerfer K et al. | Proc Natl Acad Sci U S A 2022;119(29):e2114365119 | https://doi.org/10.1073/pnas.2114365119 |
Integrating age, BMI, and serum N-glycans detected by MALDI mass spectrometry to classify suspicious mammogram findings as benign lesions or breast cancer. | Blaschke CRK, Hill EG et al. | Sci Rep 2022;12(1):20801 | https://doi.org/10.1038/s41598-022-25401-0 |
Neuroinflammation in neuronopathic Gaucher disease: Role of microglia and NK cells, biomarkers, and response to substrate reduction therapy. | Boddupalli CS, Nair S et al. | Elife 2022;11 | https://doi.org/10.7554/eLife.79830 |
MALDI Mass Spectrometry Imaging for the Distinction of Adenocarcinomas of the Pancreas and Biliary Tree. | Bollwein C, Gonҫalves JPL et al. | Molecules 2022;27(11) | https://doi.org/10.3390/molecules27113464 |
Evaluation of Quantitative Platforms for Single Target Mass Spectrometry Imaging. | Bowman AP, Sawicki J et al. | Pharmaceuticals (Basel) 2022;15(10) | https://doi.org/10.3390/ph15101180 |
High-Mannose N-Glycans as Malignant Progression Markers in Early-Stage Colorectal Cancer. | Boyaval F, Dalebout H et al. | Cancers (Basel) 2022;14(6) | https://doi.org/10.3390/cancers14061552 |
Spatial metabolomics reveals upregulation of several pyrophosphate-producing pathways in cortical bone of Hyp mice. | Buck A, Prade VM et al. | JCI Insight 2022;7(20) | https://doi.org/10.1172/jci.insight.162138 |
Metabolic tumor constitution is superior to tumor regression grading for evaluating response to neoadjuvant therapy of esophageal adenocarcinoma patients. | Buck A, Prade VM et al. | J Pathol 2022;256(2):202-213 | https://doi.org/10.1002/path.5828 |
Orthotopic Glioblastoma Models for Evaluation of the Clinical Target Volume Concept. | Bütof R, Hönscheid P et al. | Cancers (Basel) 2022;14(19) | https://doi.org/10.3390/cancers14194559 |
Protective Mechanism of Polygonum perfoliatum L. Extract on Chronic Alcoholic Liver Injury Based on UHPLC-QExactive Plus Mass Spectrometry Lipidomics and MALDI-TOF/TOF Mass Spectrometry Imaging. | Chen H, Peng L et al. | Foods 2022;11(11) | https://doi.org/10.3390/foods11111583 |
In situ metabolic profile and spatial distribution of ocular tissues: New insights into dry eye disease. | Chen X, Zhang C et al. | Ocul Surf 2022;24:51-63 | https://doi.org/10.1016/j.jtos.2021.12.013 |
Unraveling metabolic alterations in transgenic mouse model of Alzheimer's disease using MALDI MS imaging with 4-aminocinnoline-3-carboxamide matrix. | Chen Y, Hu D et al. | Anal Chim Acta 2022;1192:339337 | https://doi.org/10.1016/j.aca.2021.339337 |
Spatially revealed perfluorooctane sulfonate-induced nephrotoxicity in mouse kidney using atmospheric pressure MALDI mass spectrometry imaging. | Chen Y, Jiang L et al. | Sci Total Environ 2022;838(Pt 3):156380 | https://doi.org/10.1016/j.scitotenv.2022.156380 |
Glycosphingolipids are mediators of cancer plasticity through independent signaling pathways. | Cumin C, Huang YL et al. | Cell Rep 2022;40(7):111181 | https://doi.org/10.1016/j.celrep.2022.111181 |
'On the Spot' Digital Pathology of Breast Cancer Based on Single-Cell Mass Spectrometry Imaging. | Cuypers E, Claes BSR et al. | Anal Chem 2022;94(16):6180-6190 | https://doi.org/10.1021/acs.analchem.1c05238 |
Correlating Mass Spectrometry Imaging and Liquid Chromatography-Tandem Mass Spectrometry for Tissue-Based Pharmacokinetic Studies. | Dannhorn A, Kazanc E et al. | Metabolites 2022;12(3) | https://doi.org/10.3390/metabo12030261 |
Evaluation of Formalin-Fixed and FFPE Tissues for Spatially Resolved Metabolomics and Drug Distribution Studies. | Dannhorn A, Swales JG et al. | Pharmaceuticals (Basel) 2022;15(11) | https://doi.org/10.3390/ph15111307 |
Resolving the developmental distribution patterns of polyphenols and related primary metabolites in bilberry (Vaccinium myrtillus) fruit. | Dare AP, Günther CS et al. | Food Chem 2022;374:131703 | https://doi.org/10.1016/j.foodchem.2021.131703 |
Multicenter Evaluation of Tissue Classification by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging. | Deininger SO, Bollwein C et al. | Anal Chem 2022;94(23):8194-8201 | https://doi.org/10.1021/acs.analchem.2c00097 |
Novel Combined Enzymatic Approach to Analyze Nonsialylated N-Linked Glycans through MALDI Imaging Mass Spectrometry. | DelaCourt AT, Liang H et al. | J Proteome Res 2022;21(8):1930-1938 | https://doi.org/10.1021/acs.jproteome.2c00193 |
Spatial Multiomics of Lipids, N-Glycans, and Tryptic Peptides on a Single FFPE Tissue Section. | Denti V, Capitoli G et al. | J Proteome Res 2022;21(11):2798-2809 | https://doi.org/10.1021/acs.jproteome.2c00601 |
iMS2Net: A multiscale networking methodology to decipher metabolic synergy of organism. | Dong J, Peng Q et al. | iScience 2022;25(9):104896 | https://doi.org/10.1016/j.isci.2022.104896 |
MALDI-2 and t-MALDI-2 Mass Spectrometry Imaging. | Dreisewerd K ,Bien T ,Soltwisch J | Methods Mol Biol 2022;2437:21-40 | https://doi.org/10.1007/978-1-0716-2030-4_2 |
Spatial analysis of the glioblastoma proteome reveals specific molecular signatures and markers of survival. | Duhamel M, Drelich L et al. | Nat Commun 2022;13(1):6665 | https://doi.org/10.1038/s41467-022-34208-6 |
Dissecting the Kinetic Mechanism of Human Lysine Methyltransferase 2D and Its Interactions with the WRAD2 Complex. | Edwardes LV, Caswell SJ et al. | Biochemistry 2022;61(18):1974-1987 | https://doi.org/10.1021/acs.biochem.2c00385 |
Sphingomyelinases in retinas and optic nerve heads: Effects of ocular hypertension and ischemia. | Fan J, Liu J et al. | Exp Eye Res 2022;224:109250 | https://doi.org/10.1016/j.exer.2022.109250 |
Region-Specific and Age-Dependent Multitarget Effects of Acetylcholinesterase Inhibitor Tacrine on Comprehensive Neurotransmitter Systems. | Fridjonsdottir E, Vallianatou T et al. | ACS Chem Biol 2022;17(1):147-158 | https://doi.org/10.1021/acschembio.1c00803 |
Device-Controlled Microcondensation for Spatially Confined On-Tissue Digests in MALDI Imaging of N-Glycans. | Fülöp A, Marsching C et al. | Pharmaceuticals (Basel) 2022;15(11) | https://doi.org/10.3390/ph15111356 |
Mass Spectrometry Imaging Spatial Tissue Analysis toward Personalized Medicine. | Gonçalves JPL ,Bollwein C ,Schwamborn K | Life (Basel) 2022;12(7) | https://doi.org/10.3390/life12071037 |
MALDI-MSI: A Powerful Approach to Understand Primary Pancreatic Ductal Adenocarcinoma and Metastases. | Gonçalves JPL, Bollwein C et al. | Molecules 2022;27(15) | https://doi.org/10.3390/molecules27154811 |
High Spatial Resolution MALDI Imaging Mass Spectrometry of Fresh-Frozen Bone. | Good CJ, Neumann EK et al. | Anal Chem 2022;94(7):3165-3172 | https://doi.org/10.1021/acs.analchem.1c04604 |
In Situ N-Glycosylation Signatures of Epithelial Ovarian Cancer Tissue as Defined by MALDI Mass Spectrometry Imaging. | Grzeski M, Taube ET et al. | Cancers (Basel) 2022;14(4) | https://doi.org/10.3390/cancers14041021 |
Multimodal Imaging Mass Spectrometry of Murine Gastrointestinal Tract with Retained Luminal Content. | Guiberson ER, Good CJ et al. | J Am Soc Mass Spectrom 2022;33(6):1073-1076 | https://doi.org/10.1021/jasms.1c00360 |
iSegMSI: An Interactive Strategy to Improve Spatial Segmentation of Mass Spectrometry Imaging Data. | Guo L, Liu X et al. | Anal Chem 2022;94(42):14522-14529 | https://doi.org/10.1021/acs.analchem.2c01456 |
Cryo-ultramicrotomy and Mass Spectrometry Imaging Analysis of Nudibranch Microstructures. | Hamilton BR, Chan W et al. | J Am Soc Mass Spectrom 2022;33(3):592-597 | https://doi.org/10.1021/jasms.1c00254 |
Pharmacological inhibition of MERTK induces in vivo retinal degeneration: a multimodal imaging ocular safety assessment. | Hamm G, Maglennon G et al. | Arch Toxicol 2022;96(2):613-624 | https://doi.org/10.1007/s00204-021-03197-8 |
On-tissue derivatization for isomer-specific mass spectrometry imaging and relative quantification of monosaccharides in biological tissues. | Han Y, Zhao Y et al. | Anal Chim Acta 2022;1225:340241 | https://doi.org/10.1016/j.aca.2022.340241 |
Acute lyme disease IgG N-linked glycans contrast the canonical inflammatory signature. | Haslund-Gourley BS, Grauzam S et al. | Front Immunol 2022;13:949118 | https://doi.org/10.3389/fimmu.2022.949118 |
Multimodal Lung Cancer Subtyping Using Deep Learning Neural Networks on Whole Slide Tissue Images and MALDI MSI. | Janßen C, Boskamp T et al. | Cancers (Basel) 2022;14(24) | https://doi.org/10.3390/cancers14246181 |
Robust subtyping of non-small cell lung cancer whole sections through MALDI mass spectrometry imaging. | Janßen C, Boskamp T et al. | Proteomics Clin Appl 2022;16(4):e2100068 | https://doi.org/10.1002/prca.202100068 |
Visualizing the spatial distribution of functional metabolites in Forsythia suspensa at different harvest stages by MALDI mass spectrometry imaging. | Jing F, Wang L et al. | Fitoterapia 2022;162:105285 | https://doi.org/10.1016/j.fitote.2022.105285 |
Spatial quantitation of antibiotics in bone tissue compartments by laser-capture microdissection coupled with UHPLC-tandem mass spectrometry. | Kaya F, Zimmerman MD et al. | Anal Bioanal Chem 2022;414(23):6919-6927 | https://doi.org/10.1007/s00216-022-04257-3 |
Physiological constraints dictate toxin spatial heterogeneity in snake venom glands. | Kazandjian TD, Hamilton BR et al. | BMC Biol 2022;20(1):148 | https://doi.org/10.1186/s12915-022-01350-y |
Mass spectrometry imaging spatially identifies complex-type N-glycans as putative cartilage degradation markers in human knee osteoarthritis tissue. | Lee YR, Briggs MT et al. | Anal Bioanal Chem 2022;414(26):7597-7607 | https://doi.org/10.1007/s00216-022-04289-9 |
Multi-omics profiling of collagen-induced arthritis mouse model reveals early metabolic dysregulation via SIRT1 axis. | Li L, Freitag J et al. | Sci Rep 2022;12(1):11830 | https://doi.org/10.1038/s41598-022-16005-9 |
Reduced Hemoglobin Signal and Improved Detection of Endogenous Proteins in Blood-Rich Tissues for MALDI Mass Spectrometry Imaging. | Lin M ,Eberlin LS ,Seeley EH | J Am Soc Mass Spectrom 2022;33(2):296-303 | https://doi.org/10.1021/jasms.1c00300 |
Deep multilayer brain omics identifies the potential involvement of menopause molecular networks in Gliomas' disease progression. | Liu C, Zhang W et al. | FASEB J 2022;36(10):e22570 | https://doi.org/10.1096/fj.202200427RR |
High-throughput screening and spatial profiling of low-mass pesticides using a novel Ti3C2 MXene nanowire (TMN) as MALDI MS matrix. | Ma C, Wang X et al. | Chemosphere 2022;286(Pt 2):131826 | https://doi.org/10.1016/j.chemosphere.2021.131826 |
Sample preparation optimization of insects and zebrafish for whole-body mass spectrometry imaging. | Ma L, Xie Q et al. | Anal Bioanal Chem 2022;414(16):4777-4790 | https://doi.org/10.1007/s00216-022-04102-7 |
Matrix-assisted laser desorption/ionization mass spectrometry imaging reveals Spatial-Temporal-Content" changes of parishins in Gastrodiae Rhizoma during the steaming process." | Ma T, Sun C et al. | Food Res Int 2022;162(Pt B):112092 | https://doi.org/10.1016/j.foodres.2022.112092 |
Quaternized Acridine Maleimide MALDI Probe Enables Mass Spectrometry Imaging of Thiols. | Ma Z, Yuan J et al. | Anal Chem 2022;94(43):14917-14924 | https://doi.org/10.1021/acs.analchem.2c02292 |
On-tissue spatially resolved glycoproteomics guided by N-glycan imaging reveal global dysregulation of canine glioma glycoproteomic landscape. | Malaker SA, Quanico J et al. | Cell Chem Biol 2022;29:30-42.e4 | https://doi.org/10.1016/j.chembiol.2021.05.007 |
CD138 Is Expressed in Different Entities of Salivary Gland Cancer and Their Lymph Node Metastases and Therefore Represents a Potential Therapeutic Target. | Mayer M, Nachtsheim L et al. | Int J Mol Sci 2022;23(16) | https://doi.org/10.3390/ijms23169037 |
Utilizing imaging mass spectrometry to analyze microbial biofilm chemical responses to exogenous compounds. | McCaughey CS, Trebino MA et al. | Methods Enzymol 2022;665:281-304 | https://doi.org/10.1016/bs.mie.2021.11.014 |
Structural Characterization and Spatial Mapping of Tetrodotoxins in Australian Polyclads. | McNab JM, Briggs MT et al. | Mar Drugs 2022;20(12) | https://doi.org/10.3390/md20120788 |
Pro-inflammatory IgG1 N-glycan signature correlates with primary graft dysfunction onset in COPD patients. | McQuiston A, Scott D et al. | Transpl Immunol 2022;71:101491 | https://doi.org/10.1016/j.trim.2021.101491 |
Protein Alterations in Cardiac Ischemia/Reperfusion Revealed by Spatial-Omics. | Mezger STP, Mingels AMA et al. | Int J Mol Sci 2022;23(22) | https://doi.org/10.3390/ijms232213847 |
Mass Spectrometry Imaging of Lipids Using MALDI Coupled with Plasma-Based Post-Ionization on a Trapped Ion Mobility Mass Spectrometer. | Michael JA, Mutuku SM et al. | Anal Chem 2022;94(50):17494-17503 | https://doi.org/10.1021/acs.analchem.2c03745 |
Chemical traits of cerebral amyloid angiopathy in familial British-, Danish-, and non-Alzheimer's dementias. | Michno W, Koutarapu S et al. | J Neurochem 2022;163(3):233-246 | https://doi.org/10.1111/jnc.15694 |
Structural amyloid plaque polymorphism is associated with distinct lipid accumulations revealed by trapped ion mobility mass spectrometry imaging. | Michno W, Wehrli PM et al. | J Neurochem 2022;160(4):482-498 | https://doi.org/10.1111/jnc.15557 |
Multiomic Mass Spectrometry Imaging to Advance Future Pathological Understanding of Ocular Disease. | Millar J, Ozaki E et al. | Metabolites 2022;12(12) | https://doi.org/10.3390/metabo12121239 |
Unravelling Prostate Cancer Heterogeneity Using Spatial Approaches to Lipidomics and Transcriptomics. | Mutuku SM, Spotbeen X et al. | Cancers (Basel) 2022;14(7) | https://doi.org/10.3390/cancers14071702 |
Imaging Mass Spectrometry Reveals Alterations in N-Linked Glycosylation That Are Associated With Histopathological Changes in Nonalcoholic Steatohepatitis in Mouse and Human. | Ochoa-Rios S, O'Connor IP et al. | Mol Cell Proteomics 2022;21(5):100225 | https://doi.org/10.1016/j.mcpro.2022.100225 |
Mass Spectrometry-Based Differentiation of Oral Tongue Squamous Cell Carcinoma and Nontumor Regions With the SpiderMass Technology. | Ogrinc N, Attencourt C et al. | Front Oral Health 2022;3:827360 | https://doi.org/10.3389/froh.2022.827360 |
The metabolic landscape in chronic rotator cuff tear reveals tissue-region-specific signatures. | Olie CS, van Zeijl R et al. | J Cachexia Sarcopenia Muscle 2022;13(1):532-543 | https://doi.org/10.1002/jcsm.12873 |
Mass spectrometry imaging discriminates glioblastoma tumor cell subpopulations and different microvascular formations based on their lipid profiles. | O'Neill KC, Liapis E et al. | Sci Rep 2022;12(1):17069 | https://doi.org/10.1038/s41598-022-22093-4 |
Caffeine intake exerts dual genome-wide effects on hippocampal metabolism and learning-dependent transcription. | Paiva I, Cellai L et al. | J Clin Invest 2022;132(12) | https://doi.org/10.1172/JCI149371 |
Hornerin deposits in neuronal intranuclear inclusion disease: direct identification of proteins with compositionally biased regions in inclusions. | Park H, Yamanaka T et al. | Acta Neuropathol Commun 2022;10(1):28 | https://doi.org/10.1186/s40478-022-01333-8 |
Induction of Liver Size Reduction in Zebrafish Larvae by the Emerging Synthetic Cannabinoid 4F-MDMB-BINACA and Its Impact on Drug Metabolism. | Park YM, Dahlem C et al. | Molecules 2022;27(4) | https://doi.org/10.3390/molecules27041290 |
Multi-Class Cancer Subtyping in Salivary Gland Carcinomas with MALDI Imaging and Deep Learning. | Pertzborn D, Arolt C et al. | Cancers (Basel) 2022;14(17) | https://doi.org/10.3390/cancers14174342 |
Spatially resolved multi-omics deciphers bidirectional tumor-host interdependence in glioblastoma. | Ravi VM, Will P et al. | Cancer Cell 2022;40(6):639-655.e13 | https://doi.org/10.1016/j.ccell.2022.05.009 |
Imaging mass spectrometry reveals complex lipid distributions across Staphylococcus aureus biofilm layers. | Rivera ES, Weiss A et al. | J Mass Spectrom Adv Clin Lab 2022;26:36-46 | https://doi.org/10.1016/j.jmsacl.2022.09.003 |
Metabolic Links to Socioeconomic Stresses Uniquely Affecting Ancestry in Normal Breast Tissue at Risk for Breast Cancer. | Rujchanarong D, Scott D et al. | Front Oncol 2022;12:876651 | https://doi.org/10.3389/fonc.2022.876651 |
Atlas of exercise metabolism reveals time-dependent signatures of metabolic homeostasis. | Sato S, Dyar KA et al. | Cell Metab 2022;34(2):329-345.e8 | https://doi.org/10.1016/j.cmet.2021.12.016 |
MALDI imaging mass spectrometry: an emerging tool in neurology. | Schnackenberg LK, Thorn DA et al. | Metab Brain Dis 2022;37(1):105-121 | https://doi.org/10.1007/s11011-021-00797-2 |
Bioactive lipid screening during respiratory tract infections with bacterial and viral pathogens in mice. | Schultz D, Cuypers F et al. | Metabolomics 2022;18(6):39 | https://doi.org/10.1007/s11306-022-01898-4 |
GlycoFibroTyper: A Novel Method for the Glycan Analysis of IgG and the Development of a Biomarker Signature of Liver Fibrosis. | Scott DA, Wang M et al. | Front Immunol 2022;13:797460 | https://doi.org/10.3389/fimmu.2022.797460 |
A non-dividing cell population with high pyruvate dehydrogenase kinase activity regulates metabolic heterogeneity and tumorigenesis in the intestine. | Sebastian C, Ferrer C et al. | Nat Commun 2022;13(1):1503 | https://doi.org/10.1038/s41467-022-29085-y |
S100A4 exerts robust mucosal adjuvant activity for co-administered antigens in mice. | Sen Chaudhuri A, Yeh YW et al. | Mucosal Immunol 2022;15(5):1028-1039 | https://doi.org/10.1038/s41385-022-00535-6 |
Spatial metabolomics for evaluating response to neoadjuvant therapy in non-small cell lung cancer patients. | Shen J, Sun N et al. | Cancer Commun (Lond) 2022;42(6):517-535 | https://doi.org/10.1002/cac2.12310 |
Imaging Mass Spectrometry (IMS) for drug discovery and development survey: Results on methods, applications and regulatory compliance. | Solon E, Groseclose MR et al. | Drug Metab Pharmacokinet 2022;43:100438 | https://doi.org/10.1016/j.dmpk.2021.100438 |
MALDI Mass Spectrometry Imaging Highlights Specific Metabolome and Lipidome Profiles in Salivary Gland Tumor Tissues. | Sommella E, Salviati E et al. | Metabolites 2022;12(6) | https://doi.org/10.3390/metabo12060530 |
Spatially resolved characterization of tissue metabolic compartments in fasted and high-fat diet livers. | Stopka SA, van der Reest J et al. | PLoS One 2022;17(9):e0261803 | https://doi.org/10.1371/journal.pone.0261803 |
Method To Visualize the Intratumor Distribution and Impact of Gemcitabine in Pancreatic Ductal Adenocarcinoma by Multimodal Imaging. | Strittmatter N, Richards FM et al. | Anal Chem 2022;94(3):1795-1803 | https://doi.org/10.1021/acs.analchem.1c04579 |
MALDI Mass Spectrometry Imaging of Lipids on Free-Floating Brain Sections and Immunohistochemically Colocalized Markers of Neurodegeneration. | Strnad Š, Strnadová V et al. | Methods Mol Biol 2022;2437:229-239 | https://doi.org/10.1007/978-1-0716-2030-4_16 |
Visualizing the spatial distribution and alteration of metabolites in continuously cropped Salvia miltiorrhiza Bge using MALDI-MSI. | Sun C, Cui L et al. | J Pharm Anal 2022;12(5):719-724 | https://doi.org/10.1016/j.jpha.2021.09.011 |
FT-ICR Mass Spectrometry Imaging at Extreme Mass Resolving Power Using a Dynamically Harmonized ICR Cell with 1ω or 2ω Detection. | Tiquet M, La Rocca R et al. | Anal Chem 2022;94(26):9316-9326 | https://doi.org/10.1021/acs.analchem.2c00754 |
Exposure to solar ultraviolet radiation establishes a novel immune suppressive lipidome in skin-draining lymph nodes. | Tse BCY, Ferguson AL et al. | Front Immunol 2022;13:1045731 | https://doi.org/10.3389/fimmu.2022.1045731 |
Mapping of MeLiM melanoma combining ICP-MS and MALDI-MSI methods. | Vaníčková L, Do T et al. | Int J Biol Macromol 2022;203:583-592 | https://doi.org/10.1016/j.ijbiomac.2022.01.139 |
Spatial Mapping of Plant N-Glycosylation Cellular Heterogeneity Inside Soybean Root Nodules Provided Insights Into Legume-Rhizobia Symbiosis. | Veličković D, Liao YC et al. | Front Plant Sci 2022;13:869281 | https://doi.org/10.3389/fpls.2022.869281 |
PALP: A rapid imaging technique for stratifying ferroptosis sensitivity in normal and tumor tissues in situ. | Wang F, Graham ET et al. | Cell Chem Biol 2022;29(1):157-170.e6 | https://doi.org/10.1016/j.chembiol.2021.11.001 |
Analyzing cell-type-specific dynamics of metabolism in kidney repair. | Wang G, Heijs B et al. | Nat Metab 2022;4(9):1109-1118 | https://doi.org/10.1038/s42255-022-00615-8 |
Spatial dynamic metabolomics identifies metabolic cell fate trajectories in human kidney differentiation. | Wang G, Heijs B et al. | Cell Stem Cell 2022;29(11):1580-1593.e7 | https://doi.org/10.1016/j.stem.2022.10.008 |
PARP-inhibition reprograms macrophages toward an anti-tumor phenotype. | Wang L, Wang D et al. | Cell Rep 2022;41(2):111462 | https://doi.org/10.1016/j.celrep.2022.111462 |
A simple preparation step to remove excess liquid lipids in white adipose tissue enabling improved detection of metabolites via MALDI-FTICR imaging MS. | Wang Q, Sun N et al. | Histochem Cell Biol 2022;157(5):595-605 | https://doi.org/10.1007/s00418-022-02088-y |
Visualizing the Distribution of Lipids in Peanut Seeds by MALDI Mass Spectrometric Imaging. | Wang X, Chen Y et al. | Foods 2022;11(23) | https://doi.org/10.3390/foods11233888 |
Klebsiella pneumoniae induces host metabolic stress that promotes tolerance to pulmonary infection. | Wong Fok Lung T, Charytonowicz D et al. | Cell Metab 2022;34(5):761-774.e9 | https://doi.org/10.1016/j.cmet.2022.03.009 |
Three-Dimensional Mass Spectrometry Imaging Reveals Distributions of Lipids and the Drug Metabolite Associated with the Enhanced Growth of Colon Cancer Cell Spheroids Treated with Triclosan. | Xie P, Zhang H et al. | Anal Chem 2022;94(40):13667-13675 | https://doi.org/10.1021/acs.analchem.2c00768 |
Impact of Skin Tissue Collection Method on Downstream MALDI-Imaging. | Yadav M, Chaudhary PP et al. | Metabolites 2022;12(6) | https://doi.org/10.3390/metabo12060497 |
Optimization of Zebrafish Larvae Sectioning for Mass Spectrometry Imaging. | Yang J, Rendino L et al. | Pharmaceuticals (Basel) 2022;15(10) | https://doi.org/10.3390/ph15101230 |
In situ mass spectrometry imaging reveals heterogeneous glycogen stores in human normal and cancerous tissues. | Young LEA, Conroy LR et al. | EMBO Mol Med 2022;14(11):e16029 | https://doi.org/10.15252/emmm.202216029 |
Mapping Glucose Uptake, Transport and Metabolism in the Bovine Lens Cortex. | Zahraei A, Guo G et al. | Front Physiol 2022;13:901407 | https://doi.org/10.3389/fphys.2022.901407 |
Enhanced Spatial Mapping of Histone Proteoforms in Human Kidney Through MALDI-MSI by High-Field UHMR-Orbitrap Detection. | Zemaitis KJ, Veličković D et al. | Anal Chem 2022;94(37):12604-12613 | https://doi.org/10.1021/acs.analchem.2c01034 |
On-tissue amidation of sialic acid with aniline for sensitive imaging of sialylated N-glycans from FFPE tissue sections via MALDI mass spectrometry. | Zhang H, Shi X et al. | Anal Bioanal Chem 2022;414(18):5263-5274 | https://doi.org/10.1007/s00216-022-03894-y |
Generation and multiomic profiling of a TP53/CDKN2A double-knockout gastroesophageal junction organoid model. | Zhao H, Cheng Y et al. | Sci Transl Med 2022;14(673):eabq6146 | https://doi.org/10.1126/scitranslmed.abq6146 |
Multiplatform Metabolomics Studies of Human Cancers With NMR and Mass Spectrometry Imaging. | Zhong AB, Muti IH et al. | Front Mol Biosci 2022;9:785232 | https://doi.org/10.3389/fmolb.2022.785232 |
Application of artificial intelligence in the diagnosis and prognostic prediction of ovarian cancer. | Zhou J, Cao W et al. | Comput Biol Med 2022;146:105608 | https://doi.org/10.1016/j.compbiomed.2022.105608 |
Title | Author | Publication | Link |
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Peak learning of mass spectrometry imaging data using artificial neural networks. | Abdelmoula WM, Lopez BG et al. | Nat Commun 2021;12(1):5544 | https://doi.org/10.1038/s41467-021-25744-8 |
GD3 synthase deletion alters retinal structure and impairs visual function in mice. | Abreu CA, Teixeira-Pinheiro LC et al. | J Neurochem 2021;158:694-709 | https://doi.org/10.1111/jnc.15443 |
Spatial differentiation of metabolism in prostate cancer tissue by MALDI-TOF MSI. | Andersen MK, Høiem TS et al. | Cancer Metab 2021;9(1):9 | https://doi.org/10.1186/s40170-021-00242-z |
Electroblotting through Enzymatic Membranes to Enhance Molecular Tissue Imaging. | Andrews WT, Bickner AN et al. | J Am Soc Mass Spectrom 2021;32:1689-1699 | https://doi.org/10.1021/jasms.1c00046 |
Visualizing Cholesterol in the Brain by On-Tissue Derivatization and Quantitative Mass Spectrometry Imaging. | Angelini R, Yutuc E et al. | Anal Chem 2021;93(11):4932-4943 | https://doi.org/10.1021/acs.analchem.0c05399 |
Machine learning for grading and prognosis of esophageal dysplasia using mass spectrometry and histological imaging. | Beuque M, Martin-Lorenzo M et al. | Comput Biol Med 2021;138:104918 | https://doi.org/10.1016/j.compbiomed.2021.104918 |
Molecular insights into symbiosis-mapping sterols in a marine flatworm-algae-system using high spatial resolution MALDI-2-MS imaging with ion mobility separation. | Bien T, Hambleton EA et al. | Anal Bioanal Chem 2021;413:2767-2777 | https://doi.org/10.1007/s00216-020-03070-0 |
Direct N-Glycosylation Profiling of Urine and Prostatic Fluid Glycoproteins and Extracellular Vesicles. | Blaschke CRK, Hartig JP et al. | Front Chem 2021;9:734280 | https://doi.org/10.3389/fchem.2021.734280 |
Cross-Normalization of MALDI Mass Spectrometry Imaging Data Improves Site-to-Site Reproducibility. | Boskamp T, Casadonte R et al. | Anal Chem 2021;93(30):10584-10592 | https://doi.org/10.1021/acs.analchem.1c01792 |
N-Glycomic Signature of Stage II Colorectal Cancer and Its Association With the Tumor Microenvironment. | Boyaval F, van Zeijl R et al. | Mol Cell Proteomics 2021;20:100057 | https://doi.org/10.1074/mcp.RA120.002215 |
GSK-3 Inhibition Is Cytotoxic in Glioma Stem Cells through Centrosome Destabilization and Enhances the Effect of Radiotherapy in Orthotopic Models. | Brüning-Richardson A, Shaw GC et al. | Cancers (Basel) 2021;13(23) | https://doi.org/10.3390/cancers13235939 |
Use of MALDI Mass Spectrometry Imaging to Identify Proteomic Signatures in Aortic Aneurysms after Endovascular Repair. | Buerger M, Klein O et al. | Biomedicines 2021;9(9) | https://doi.org/10.3390/biomedicines9091088 |
Lipidomic Profiling of Clinical Prostate Cancer Reveals Targetable Alterations in Membrane Lipid Composition. | Butler LM, Mah CY et al. | Cancer Res 2021;81(19):4981-4993 | https://doi.org/10.1158/0008-5472.CAN-20-3863 |
Mass spectrometry imaging of L-[ring-13C6]-labeled phenylalanine and tyrosine kinetics in non-small cell lung carcinoma. | Cao J, Balluff B et al. | Cancer Metab 2021;9(1):26 | https://doi.org/10.1186/s40170-021-00262-9 |
Imaging Mass Spectrometry-Based Proteomic Analysis to Differentiate Melanocytic Nevi and Malignant Melanoma. | Casadonte R, Kriegsmann M et al. | Cancers (Basel) 2021;13(13) | https://doi.org/10.3390/cancers13133197 |
Visualization of HIV-1 reservoir: an imaging perspective. | Chapon C, Moysi E et al. | Curr Opin HIV AIDS 2021;16(4):232-239 | https://doi.org/10.1097/COH.0000000000000691 |
Trends in oligomannosylation and α1,2-mannosidase expression in human cancers. | Chatterjee S, Ugonotti J et al. | Oncotarget 2021;12(21):2188-2205 | https://doi.org/10.18632/oncotarget.28064 |
Mass spectrometry imaging revealed alterations of lipid metabolites in multicellular tumor spheroids in response to hydroxychloroquine. | Chen Y, Wang T et al. | Anal Chim Acta 2021;1184:339011 | https://doi.org/10.1016/j.aca.2021.339011 |
Multiplexed imaging mass spectrometry of the extracellular matrix using serial enzyme digests from formalin-fixed paraffin-embedded tissue sections. | Clift CL, Drake RR et al. | Anal Bioanal Chem 2021;413:2709-2719 | https://doi.org/10.1007/s00216-020-03047-z |
Proteomic Analysis Identifies FNDC1, A1BG, and Antigen Processing Proteins Associated with Tumor Heterogeneity and Malignancy in a Canine Model of Breast Cancer. | Cordeiro YG, Mulder LM et al. | Cancers (Basel) 2021;13(23) | https://doi.org/10.3390/cancers13235901 |
Muscle metabolic remodelling patterns in Duchenne muscular dystrophy revealed by ultra-high-resolution mass spectrometry imaging. | Dabaj I, Ferey J et al. | Sci Rep 2021;11(1):1906 | https://doi.org/10.1038/s41598-021-81090-1 |
N-Glycosylation Patterns Correlate with Hepatocellular Carcinoma Genetic Subtypes. | DelaCourt A, Black A et al. | Mol Cancer Res 2021;19(11):1868-1877 | https://doi.org/10.1158/1541-7786.MCR-21-0348 |
Reproducible Lipid Alterations in Patient-Derived Breast Cancer Xenograft FFPE Tissue Identified with MALDI MSI for Pre-Clinical and Clinical Application. | Denti V, Andersen MK et al. | Metabolites 2021;11(9) | https://doi.org/10.3390/metabo11090577 |
Lipidomic Typing of Colorectal Cancer Tissue Containing Tumour-Infiltrating Lymphocytes by MALDI Mass Spectrometry Imaging. | Denti V, Mahajneh A et al. | Metabolites 2021;11(9) | https://doi.org/10.3390/metabo11090599 |
Lesion Penetration and Activity Limit the Utility of Second-Line Injectable Agents in Pulmonary Tuberculosis. | Ernest JP, Sarathy J et al. | Antimicrob Agents Chemother 2021;65(10):e0050621 | https://doi.org/10.1128/AAC.00506-21 |
Heterogeneity of Lipid and Protein Cartilage Profiles Associated with Human Osteoarthritis with or without Type 2 Diabetes Mellitus. | Eveque-Mourroux MR, Emans PJ et al. | J Proteome Res 2021;20(5):2973-2982 | https://doi.org/10.1021/acs.jproteome.1c00186 |
Molecular Mapping of Neutral Lipids Using Silicon Nanopost Arrays and TIMS Imaging Mass Spectrometry. | Fincher JA, Djambazova KV et al. | J Am Soc Mass Spectrom 2021;32(10):2519-2527 | https://doi.org/10.1021/jasms.1c00159 |
Comparison of Osteosarcoma Aggregated Tumour Models with Human Tissue by Multimodal Mass Spectrometry Imaging. | Flint LE, Hamm G et al. | Metabolites 2021;11(8) | https://doi.org/10.3390/metabo11080506 |
Mass spectrometry imaging identifies abnormally elevated brain l-DOPA levels and extrastriatal monoaminergic dysregulation in l-DOPA-induced dyskinesia. | Fridjonsdottir E, Shariatgorji R et al. | Sci Adv 2021;7(2) | https://doi.org/10.1126/sciadv.abe5948 |
Connecting structure and function from organisms to molecules in small-animal symbioses through chemo-histo-tomography. | Geier B, Oetjen J et al. | Proc Natl Acad Sci U S A 2021;118(27) | https://doi.org/10.1073/pnas.2023773118 |
Integrative Metabolomics Reveals Deep Tissue and Systemic Metabolic Remodeling in Glioblastoma. | Gilard V, Ferey J et al. | Cancers (Basel) 2021;13(20) | https://doi.org/10.3390/cancers13205157 |
The Impact of Histological Annotations for Accurate Tissue Classification Using Mass Spectrometry Imaging. | Gonçalves JPL, Bollwein C et al. | Metabolites 2021;11(11) | https://doi.org/10.3390/metabo11110752 |
Lipid Analysis of Fracture Hematoma With MALDI-MSI: Specific Lipids are Associated to Bone Fracture Healing Over Time. | Groven RVM, Nauta SP et al. | Front Chem 2021;9:780626 | https://doi.org/10.3389/fchem.2021.780626 |
Data Filtering and Its Prioritization in Pipelines for Spatial Segmentation of Mass Spectrometry Imaging. | Guo L, Hu Z et al. | Anal Chem 2021;93(11):4788-4793 | https://doi.org/10.1021/acs.analchem.0c05242 |
Transcriptomic, peptidomic, and mass spectrometry imaging analysis of the brain in the ant Cataglyphis nodus. | Habenstein J, Schmitt F et al. | J Neurochem 2021;158:391-412 | https://doi.org/10.1111/jnc.15346 |
Path to Clonal Theranostics in Luminal Breast Cancers. | Hajjaji N, Aboulouard S et al. | Front Oncol 2021;11:802177 | https://doi.org/10.3389/fonc.2021.802177 |
Complementing Matrix-Assisted Laser Desorption Ionization-Mass Spectrometry Imaging with Chromatography Data for Improved Assignment of Isobaric and Isomeric Phospholipids Utilizing Trapped Ion Mobility-Mass Spectrometry. | Helmer PO, Nordhorn ID et al. | Anal Chem 2021;93:2135-2143 | https://doi.org/10.1021/acs.analchem.0c03942 |
Registration of Image Modalities for Analyses of Tissue Samples Using 3D Image Modelling. | Hermann J, Brehmer K et al. | Proteomics Clin Appl 2021;15(1):e1900143 | https://doi.org/10.1002/prca.201900143 |
An imaging mass spectrometry atlas of lipids in the human neurologically normal and Huntington's disease caudate nucleus. | Hunter M, Demarais NJ et al. | J Neurochem 2021;157:2158-2172 | https://doi.org/10.1111/jnc.15325 |
Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging of Phospholipid Changes in a Drosophila Model of Early Amyotrophic Lateral Sclerosis. | Jang HJ, Le MUT et al. | J Am Soc Mass Spectrom 2021;32(10):2536-2545 | https://doi.org/10.1021/jasms.1c00167 |
Biopolymer Patterning-Directed Secretion in Mucoid and Nonmucoid Strains of Pseudomonas aeruginosa Revealed by Multimodal Chemical Imaging. | Jia J, Ellis JF et al. | ACS Infect Dis 2021;7(3):598-607 | https://doi.org/10.1021/acsinfecdis.0c00765 |
Classification of Molecular Subtypes of High-Grade Serous Ovarian Cancer by MALDI-Imaging. | Kassuhn W, Klein O et al. | Cancers (Basel) 2021;13(7) | https://doi.org/10.3390/cancers13071512 |
Protease-dependent defects in N-cadherin processing drive PMM2-CDG pathogenesis. | Klaver EJ, Dukes-Rimsky L et al. | JCI Insight 2021;6(24) | https://doi.org/10.1172/jci.insight.153474 |
Toward Revealing Microcystin Distribution in Mouse Liver Tissue Using MALDI-MS Imaging. | Kucheriavaia D, Veličković D et al. | Toxins (Basel) 2021;13(10) | https://doi.org/10.3390/toxins13100709 |
Patterns of Carbon-Bound Exogenous Compounds in Patients with Lung Cancer and Association with Disease Pathophysiology. | Kunzke T, Prade VM et al. | Cancer Res 2021;81(23):5862-5875 | https://doi.org/10.1158/0008-5472.CAN-21-1175 |
MALDI-IMS combined with shotgun proteomics identify and localize new factors in male infertility. | Lahiri S, Aftab W et al. | Life Sci Alliance 2021;4(3) | https://doi.org/10.26508/lsa.202000672 |
Absolute quantification of 2-hydroxyglutarate on tissue by matrix-assisted laser desorption/ionization mass spectrometry imaging for rapid and precise identification of isocitrate dehydrogenase mutations in human glioma. | Lan C, Li H et al. | Int J Cancer 2021;149(12):2091-2098 | https://doi.org/10.1002/ijc.33729 |
Mitochondrial Ndufa4l2 Enhances Deposition of Lipids and Expression of Ca9 in the TRACK Model of Early Clear Cell Renal Cell Carcinoma. | Laursen KB, Chen Q et al. | Front Oncol 2021;11:783856 | https://doi.org/10.3389/fonc.2021.783856 |
Therapeutic Potential of Fosmanogepix (APX001) for Intra-abdominal Candidiasis: from Lesion Penetration to Efficacy in a Mouse Model. | Lee A, Wang N et al. | Antimicrob Agents Chemother 2021;65 | https://doi.org/10.1128/AAC.02476-20 |
A digital single-molecule nanopillar SERS platform for predicting and monitoring immune toxicities in immunotherapy. | Li J, Wuethrich A et al. | Nat Commun 2021;12(1):1087 | https://doi.org/10.1038/s41467-021-21431-w |
Three-Dimensional Imaging of Whole-Body Zebrafish Revealed Lipid Disorders Associated with Niemann-Pick Disease Type C1. | Liang X, Cao S et al. | Anal Chem 2021;93:8178-8187 | https://doi.org/10.1021/acs.analchem.1c00196 |
Spatially Resolved Metabolomics and Lipidomics Reveal Salinity and Drought-Tolerant Mechanisms of Cottonseeds. | Liu B, Wang X et al. | J Agric Food Chem 2021;69(28):8028-8037 | https://doi.org/10.1021/acs.jafc.1c01598 |
Examination of lipid profiles in abdominal fascial healing using MALDI-TOF to identify potential therapeutic targets. | Liu H, Cao J et al. | J Mass Spectrom Adv Clin Lab 2021;20:35-41 | https://doi.org/10.1016/j.jmsacl.2021.06.002 |
Peptide Signatures for Prognostic Markers of Pancreatic Cancer by MALDI Mass Spectrometry Imaging. | Loch FN, Klein O et al. | Biology (Basel) 2021;10(10) | https://doi.org/10.3390/biology10101033 |
Tumor resistance to ferroptosis driven by Stearoyl-CoA Desaturase-1 (SCD1) in cancer cells and Fatty Acid Biding Protein-4 (FABP4) in tumor microenvironment promote tumor recurrence. | Luis G, Godfroid A et al. | Redox Biol 2021;43:102006 | https://doi.org/10.1016/j.redox.2021.102006 |
A Mass Spectrometry Imaging Based Approach for Prognosis Prediction in UICC Stage I/II Colon Cancer. | Martin B, Gonçalves JPL et al. | Cancers (Basel) 2021;13(21) | https://doi.org/10.3390/cancers13215371 |
Rapid visualization of lipopeptides and potential bioactive groups of compounds by combining ion mobility and MALDI imaging mass spectrometry. | McCann A, Kune C et al. | Drug Discov Today Technol 2021;39:81-88 | https://doi.org/10.1016/j.ddtec.2021.08.003 |
Imaging Mass Spectrometry and Lectin Analysis of N-Linked Glycans in Carbohydrate Antigen-Defined Pancreatic Cancer Tissues. | McDowell CT, Klamer Z et al. | Mol Cell Proteomics 2021;20:100012 | https://doi.org/10.1074/mcp.RA120.002256 |
Study of the Distribution of Acetaminophen and Its Metabolites in Rats, from the Whole-Body to Isolated Organ Levels, by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging after On-Tissue Chemical Derivatization. | Merdas M, Lagarrigue M et al. | Anal Chem 2021;93(39):13242-13250 | https://doi.org/10.1021/acs.analchem.1c02487 |
Mass Spectrometry Spatial-Omics on a Single Conductive Slide. | Mezger STP, Mingels AMA et al. | Anal Chem 2021;93:2527-2533 | https://doi.org/10.1021/acs.analchem.0c04572 |
Cancer Tissue Classification Using Supervised Machine Learning Applied to MALDI Mass Spectrometry Imaging. | Mittal P, Condina MR et al. | Cancers (Basel) 2021;13(21) | https://doi.org/10.3390/cancers13215388 |
Lipid signature of advanced human carotid atherosclerosis assessed by mass spectrometry imaging. | Moerman AM, Visscher M et al. | J Lipid Res 2021;62:100020 | https://doi.org/10.1194/jlr.RA120000974 |
Complementary Lipidomic, Proteomic, and Mass Spectrometry Imaging Approach to the Characterization of the Acute Effects of Radiation in the Non-human Primate Mesenteric Lymph Node after Partial-body Irradiation with Minimal Bone Marrow Sparing. | Muller L, Huang W et al. | Health Phys 2021;121(4):372-383 | https://doi.org/10.1097/HP.0000000000001470 |
Imaging lipids in biological samples with surface-assisted laser desorption/ionization mass spectrometry: A concise review of the last decade. | Müller WH, De Pauw E et al. | Prog Lipid Res 2021;83:101114 | https://doi.org/10.1016/j.plipres.2021.101114 |
Spatial metabolomics using imaging mass spectrometry to identify the localization of asparaptine A in Asparagus officinalis. | Nakabayashi R, Hashimoto K et al. | Plant Biotechnol (Tokyo) 2021;38(3):311-315 | https://doi.org/10.5511/plantbiotechnology.21.0504b |
A new technological approach in diagnostic pathology: mass spectrometry imaging-based metabolomics for biomarker detection in urachal cancer. | Neumann JM, Niehaus K et al. | Lab Invest 2021;101:1281-1288 | https://doi.org/10.1038/s41374-021-00612-7 |
A new technological approach in diagnostic pathology: mass spectrometry imaging-based metabolomics for biomarker detection in urachal cancer. | Neumann JM, Niehaus K et al. | Lab Invest 2021;101(9):1281-1288 | https://doi.org/10.1038/s41374-021-00612-7 |
Mass spectrometry-based protein identification in proteomics-a review. | Noor Z, Ahn SB et al. | Brief Bioinform 2021;22(2):1620-1638 | https://doi.org/10.1093/bib/bbz163 |
Tryptophan metabolism is inversely regulated in the tumor and blood of patients with glioblastoma. | Panitz V, Končarević S et al. | Theranostics 2021;11(19):9217-9233 | https://doi.org/10.7150/thno.60679 |
MALDI-IMS as a Tool to Determine the Myocardial Response to Syndecan-2-Selected Mesenchymal Stromal Cell Application in an Experimental Model of Diabetic Cardiomyopathy. | Pappritz K, Klein O et al. | Proteomics Clin Appl 2021;15(1):e2000050 | https://doi.org/10.1002/prca.202000050 |
Fast Nanoliter-Scale Cell Assays Using Droplet Microarray-Mass Spectrometry Imaging. | RamalloGuevara C, Paulssen D et al. | Adv Biol (Weinh) 2021;5(3):e2000279 | https://doi.org/10.1002/adbi.202000279 |
Mineralization of 3D Osteogenic Model Based on Gelatin-Dextran Hybrid Hydrogel Scaffold Bioengineered with Mesenchymal Stromal Cells: A Multiparametric Evaluation. | Re F, Sartore L et al. | Materials (Basel) 2021;14(14) | https://doi.org/10.3390/ma14143852 |
Complete spatial characterisation of N-glycosylation upon striatal neuroinflammation in the rodent brain. | Rebelo AL, Gubinelli F et al. | J Neuroinflammation 2021;18(1):116 | https://doi.org/10.1186/s12974-021-02163-6 |
Safety, Tissue Distribution, and Metabolism of LNA-Containing Antisense Oligonucleotides in Rats. | Romero-Palomo F, Festag M et al. | Toxicol Pathol 2021;49:1174-1192 | https://doi.org/10.1177/01926233211011615 |
Defining the Tumor Microenvironment by Integration of Immunohistochemistry and Extracellular Matrix Targeted Imaging Mass Spectrometry. | Rujchanarong D, Lefler J et al. | Cancers (Basel) 2021;13(17) | https://doi.org/10.3390/cancers13174419 |
Clinical importance of high-mannose, fucosylated, and complex N-glycans in breast cancer metastasis. | Ščupáková K, Adelaja OT et al. | JCI Insight 2021;6(24) | https://doi.org/10.1172/jci.insight.146945 |
CRL4AMBRA1 is a master regulator of D-type cyclins. | Simoneschi D, Rona G et al. | Nature 2021;592(7856):789-793 | https://doi.org/10.1038/s41586-021-03445-y |
Elaboration Pipeline for the Management of MALDI-MS Imaging Datasets. | Smith A, Piga I et al. | Methods Mol Biol 2021;2361:129-142 | https://doi.org/10.1007/978-1-0716-1641-3_8 |
Traumatic brain injury induces region-specific glutamate metabolism changes as measured by multiple mass spectrometry methods. | Sowers JL, Sowers ML et al. | iScience 2021;24(10):103108 | https://doi.org/10.1016/j.isci.2021.103108 |
Inhibition of Ganglioside Synthesis Suppressed Liver Cancer Cell Proliferation through Targeting Kinetochore Metaphase Signaling. | Su T, Qin XY et al. | Metabolites 2021;11(3) | https://doi.org/10.3390/metabo11030167 |
Visualizing the distributions and spatiotemporal changes of metabolites in Panax notoginseng by MALDI mass spectrometry imaging. | Sun C, Ma S et al. | J Ginseng Res 2021;45(6):726-733 | https://doi.org/10.1016/j.jgr.2021.04.001 |
Integration of Mass Spectrometry Imaging and Machine Learning Visualizes Region-Specific Age-Induced and Drug-Target Metabolic Perturbations in the Brain. | Vallianatou T, Shariatgorji R et al. | ACS Chem Neurosci 2021;12(10):1811-1823 | https://doi.org/10.1021/acschemneuro.1c00103 |
Rapid Automated Annotation and Analysis of N-Glycan Mass Spectrometry Imaging Data Sets Using NGlycDB in METASPACE. | Veličković D, Bečejac T et al. | Anal Chem 2021;93(40):13421-13425 | https://doi.org/10.1021/acs.analchem.1c02347 |
Activation of the integrated stress response confers vulnerability to mitoribosome-targeting antibiotics in melanoma. | Vendramin R, Katopodi V et al. | J Exp Med 2021;218(9) | https://doi.org/10.1084/jem.20210571 |
Experimental and Data Analysis Considerations for Three-Dimensional Mass Spectrometry Imaging in Biomedical Research. | Vos DRN, Ellis SR et al. | Mol Imaging Biol 2021;23:149-159 | https://doi.org/10.1007/s11307-020-01541-5 |
On-Slide Heat Sterilization Enables Mass Spectrometry Imaging of Tissue Infected with High-Threat Pathogens Outside of Biocontainment: A Study Directed at Mycobacterium tuberculosis. | Wang N, Sarathy JP et al. | J Am Soc Mass Spectrom 2021;32(11):2664-2674 | https://doi.org/10.1021/jasms.1c00205 |
Spatial-resolved metabolomics reveals tissue-specific metabolic reprogramming in diabetic nephropathy by using mass spectrometry imaging. | Wang Z, Fu W et al. | Acta Pharm Sin B 2021;11(11):3665-3677 | https://doi.org/10.1016/j.apsb.2021.05.013 |
Clostridioides difficile infection induces a rapid influx of bile acids into the gut during colonization of the host. | Wexler AG, Guiberson ER et al. | Cell Rep 2021;36(10):109683 | https://doi.org/10.1016/j.celrep.2021.109683 |
Trophoblast Cell Surface Antigen 2 (Trop-2) Protein is Highly Expressed in Salivary Gland Carcinomas and Represents a Potential Therapeutic Target. | Wolber P, Nachtsheim L et al. | Head Neck Pathol 2021;15:1147-1155 | https://doi.org/10.1007/s12105-021-01325-5 |
Icaritin Provides Neuroprotection in Parkinson's Disease by Attenuating Neuroinflammation, Oxidative Stress, and Energy Deficiency. | Wu H, Liu X et al. | Antioxidants (Basel) 2021;10(4) | https://doi.org/10.3390/antiox10040529 |
Discovery of Spatial Peptide Signatures for Neuroblastoma Risk Assessment by MALDI Mass Spectrometry Imaging. | Wu Z, Hundsdoerfer P et al. | Cancers (Basel) 2021;13(13) | https://doi.org/10.3390/cancers13133184 |
Lipidomic Analysis Reveals the Protection Mechanism of GLP-1 Analogue Dulaglutide on High-Fat Diet-Induced Chronic Kidney Disease in Mice. | Yeung MHY, Leung KL et al. | Front Pharmacol 2021;12:777395 | https://doi.org/10.3389/fphar.2021.777395 |
Integration of omics analysis and atmospheric pressure MALDI mass spectrometry imaging reveals the cadmium toxicity on female ICR mouse. | Zeng T, Guo W et al. | Sci Total Environ 2021;801:149803 | https://doi.org/10.1016/j.scitotenv.2021.149803 |
Airborne fine particulate matter induces cognitive and emotional disorders in offspring mice exposed during pregnancy. | Zhao C, Xie P et al. | Sci Bull (Beijing) 2021;66(6):578-591 | https://doi.org/10.1016/j.scib.2020.08.036 |
A Small Molecule Coordinates Symbiotic Behaviors in a Host Organ. | Zink KE, Ludvik DA et al. | mBio 2021;12(2) | https://doi.org/10.1128/mBio.03637-20 |
MALDI mass Spectrometry based proteomics for drug discovery & development. | Zubair F | Drug Discov Today Technol 2021;40:29-35 | https://doi.org/10.1016/j.ddtec.2021.09.002 |
Title | Author | Publication | Link |
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Simultaneous Detection of Zinc and Its Pathway Metabolites Using MALDI MS Imaging of Prostate Tissue. | Andersen MK, Krossa S et al. | Anal Chem 2020;92:3171-3179 | https://doi.org/10.1021/acs.analchem.9b04903 |
In situ metabolite and lipid analysis of GluN2D-/- and wild-type mice after ischemic stroke using MALDI MSI. | Andrews WT, Donahue D et al. | Anal Bioanal Chem 2020;412(24):6275-6285 | https://doi.org/10.1007/s00216-020-02477-z |
Extracellular matrix alterations in low-grade lung adenocarcinoma compared with normal lung tissue by imaging mass spectrometry. | Angel PM, Bruner E et al. | J Mass Spectrom 2020;55:e4450 | https://doi.org/10.1002/jms.4450 |
Zonal regulation of collagen-type proteins and posttranslational modifications in prostatic benign and cancer tissues by imaging mass spectrometry. | Angel PM, Spruill L et al. | Prostate 2020;80(13):1071-1086 | https://doi.org/10.1002/pros.24031 |
Imaging Study by Mass Spectrometry of the Spatial Variation of Cellulose and Hemicellulose Structures in Corn Stalks. | Arnaud B, Durand S et al. | J Agric Food Chem 2020;68(13):4042-4050 | https://doi.org/10.1021/acs.jafc.9b07579 |
MALDI-TOF Mass Spectrometry Revealed Significant Lipid Variations in Follicular Fluid and Somatic Follicular Cells but Not in Enclosed Oocytes between the Large Dominant and Small Subordinate Follicles in Bovine Ovary. | Bertevello PS, Teixeira-Gomes AP et al. | Int J Mol Sci 2020;21(18) | https://doi.org/10.3390/ijms21186661 |
µ Opioid Receptor Agonism for L-DOPA-Induced Dyskinesia in Parkinson's Disease. | Bezard E, Li Q et al. | J Neurosci 2020;40(35):6812-6819 | https://doi.org/10.1523/JNEUROSCI.0610-20.2020 |
Visualizing Microbial Community Dynamics via a Controllable Soil Environment. | Bhattacharjee A, Velickovic D et al. | mSystems 2020;5(1) | https://doi.org/10.1128/mSystems.00645-19 |
Detection of small molecule concentration gradients in ocular tissues and humours. | Boughton BA, Thomas ORB et al. | J Mass Spectrom 2020;55:e4460 | https://doi.org/10.1002/jms.4460 |
N-glycomic signature of stage II colorectal cancer and its association with the tumor microenvironment. | Boyaval F, Van Zeijl R et al. | Mol Cell Proteomics 2020 | https://doi.org/10.1074/mcp.RA120.002215 |
Welding fume inhalation exposure and high-fat diet change lipid homeostasis in rat liver. | Boyce GR, Shoeb M et al. | Toxicol Rep 2020;7:1350-1355 | https://doi.org/10.1016/j.toxrep.2020.10.008 |
A Simple and Effective Sample Preparation Strategy for MALDI-MS Imaging of Neuropeptide Changes in the Crustacean Brain Due to Hypoxia and Hypercapnia Stress. | Buchberger AR, Vu NQ et al. | J Am Soc Mass Spectrom 2020;31(5):1058-1065 | https://doi.org/10.1021/jasms.9b00107 |
MALDI-MSI spatially maps N-glycan alterations to histologically distinct pulmonary pathologies following irradiation. | Carter CL, Parker GA et al. | Sci Rep 2020;10(1):11559 | https://doi.org/10.1038/s41598-020-68508-y |
Antigen Retrieval and Its Effect on the MALDI-MSI of Lipids in Formalin-Fixed Paraffin-Embedded Tissue. | Denti V, Piga I et al. | J Am Soc Mass Spectrom 2020;31:1619-1624 | https://doi.org/10.1021/jasms.0c00208 |
MS Imaging-Guided Microproteomics for Spatial Omics on a Single Instrument. | Dewez F, Oejten J et al. | Proteomics 2020;20:e1900369 | https://doi.org/10.1002/pmic.201900369 |
MALDI MSI Reveals the Spatial Distribution of Protein Markers in Tracheobronchial Lymph Nodes and Lung of Pigs after Respiratory Infection. | Do T, Guran R et al. | Molecules 2020;25(23) | https://doi.org/10.3390/molecules25235723 |
Defining the human kidney N-glycome in normal and cancer tissues using MALDI imaging mass spectrometry. | Drake RR, McDowell C et al. | J Mass Spectrom 2020;55:e4490 | https://doi.org/10.1002/jms.4490 |
Validation of MALDI-MS imaging data of selected membrane lipids in murine brain with and without laser postionization by quantitative nano-HPLC-MS using laser microdissection. | Eiersbrock FB ,Orthen JM ,Soltwisch J | Anal Bioanal Chem 2020;412(25):6875-6886 | https://doi.org/10.1007/s00216-020-02818-y |
Spatial metabolomics of in situ host-microbe interactions at the micrometre scale. | Geier B, Sogin EM et al. | Nat Microbiol 2020;5(3):498-510 | https://doi.org/10.1038/s41564-019-0664-6 |
Revealing the Regional Localization and Differential Lung Retention of Inhaled Compounds by Mass Spectrometry Imaging. | Hamm GR, Bäckström E et al. | J Aerosol Med Pulm Drug Deliv 2020;33:43-53 | https://doi.org/10.1089/jamp.2019.1536 |
MALDI-2 for the Enhanced Analysis of N-Linked Glycans by Mass Spectrometry Imaging. | Heijs B, Potthoff A et al. | Anal Chem 2020;92(20):13904-13911 | https://doi.org/10.1021/acs.analchem.0c02732 |
Simultaneous mass spectrometry imaging of multiple neuropeptides in the brain and alterations induced by experimental parkinsonism and L-DOPA therapy. | Hulme H, Fridjonsdottir E et al. | Neurobiol Dis 2020;137:104738 | https://doi.org/10.1016/j.nbd.2020.104738 |
Sample preparation strategies for high-throughput mass spectrometry imaging of primary tumor organoids. | Johnson J, Sharick JT et al. | J Mass Spectrom 2020;55:e4452 | https://doi.org/10.1002/jms.4452 |
Glioblastoma multiforme: Metabolic differences to peritumoral tissue and IDH-mutated gliomas revealed by mass spectrometry imaging. | Kampa JM, Kellner U et al. | Neuropathology 2020;40(6):546-558 | https://doi.org/10.1111/neup.12671 |
Mass spectrometry imaging reveals lipid upregulation and bile acid changes indicating amitriptyline induced steatosis in a rat model. | Kampa JM, Sahin M et al. | Toxicol Lett 2020;325:43-50 | https://doi.org/10.1016/j.toxlet.2020.02.007 |
Multiplex enzyme activity imaging by MALDI-IMS of substrate library conversions. | Klein O, Haeckel A et al. | Sci Rep 2020;10(1):15522 | https://doi.org/10.1038/s41598-020-72436-2 |
Comparison of Dietary Oils with Different Polyunsaturated Fatty Acid n-3 and n-6 Content in the Rat Model of Cutaneous Wound Healing. | Komprda T, Sladek Z et al. | Int J Mol Sci 2020;21(21) | https://doi.org/10.3390/ijms21217911 |
Discovery of Prognostic Markers for Early-Stage High-Grade Serous Ovarian Cancer by Maldi-Imaging. | Kulbe H, Klein O et al. | Cancers (Basel) 2020;12(8) | https://doi.org/10.3390/cancers12082000 |
Derangements of amino acids in cachectic skeletal muscle are caused by mitochondrial dysfunction. | Kunzke T, Buck A et al. | J Cachexia Sarcopenia Muscle 2020;11(1):226-240 | https://doi.org/10.1002/jcsm.12498 |
Hepatotoxic effects of inhalation exposure to polycyclic aromatic hydrocarbons on lipid metabolism of C57BL/6 mice. | Li F, Xiang B et al. | Environ Int 2020;134:105000 | https://doi.org/10.1016/j.envint.2019.105000 |
Peak detection for MALDI mass spectrometry imaging data using sparse frame multipliers. | Lieb F ,Boskamp T ,Stark HG | J Proteomics 2020;225:103852 | https://doi.org/10.1016/j.jprot.2020.103852 |
Storage Conditions of Human Kidney Tissue Sections Affect Spatial Lipidomics Analysis Reproducibility. | Lukowski JK, Pamreddy A et al. | J Am Soc Mass Spectrom 2020;31:2538-2546 | https://doi.org/10.1021/jasms.0c00256 |
Evaluation of Data Analysis Platforms and Compatibility with MALDI-TOF Imaging Mass Spectrometry Data Sets. | Luu GT, Condren AR et al. | J Am Soc Mass Spectrom 2020;31(6):1313-1320 | https://doi.org/10.1021/jasms.0c00039 |
Imaging Mass Spectrometry and Lectin Analysis of N-linked Glycans in Carbohydrate Antigen Defined Pancreatic Cancer Tissues. | McDowell CT, Klamer Z et al. | Mol Cell Proteomics 2020 | https://doi.org/10.1074/mcp.RA120.002256 |
Chemical imaging of evolving amyloid plaque pathology and associated Aβ peptide aggregation in a transgenic mouse model of Alzheimer's disease. | Michno W, Wehrli P et al. | J Neurochem 2020;152:602-616 | https://doi.org/10.1111/jnc.14888 |
Lipid signature of advanced human carotid atherosclerosis assessed by mass spectrometry imaging. | Moerman AM, Visscher M et al. | J Lipid Res 2020 | https://doi.org/10.1194/jlr.RA120000974 |
A Co-registration Pipeline for Multimodal MALDI and Confocal Imaging Analysis of Stem Cell Colonies. | Nikitina A, Huang D et al. | J Am Soc Mass Spectrom 2020;31(4):986-989 | https://doi.org/10.1021/jasms.9b00094 |
Localized Metabolomic Gradients in Patient-Derived Xenograft Models of Glioblastoma. | Randall EC, Lopez BGC et al. | Cancer Res 2020;80:1258-1267 | https://doi.org/10.1158/0008-5472.CAN-19-0638 |
Unique and highly specific cyanogenic glycoside localization in stigmatic cells and pollen in the genus Lomatia (Proteaceae). | Ritmejerytė E, Boughton BA et al. | Ann Bot 2020;126(3):387-400 | https://doi.org/10.1093/aob/mcaa038 |
Dual Mass Spectrometric Tissue Imaging of Nanocarrier Distributions and Their Biochemical Effects. | Sikora KN, Hardie JM et al. | Anal Chem 2020;92:2011-2018 | https://doi.org/10.1021/acs.analchem.9b04398 |
Detecting Proteomic Indicators to Distinguish Diabetic Nephropathy from Hypertensive Nephrosclerosis by Integrating Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging with High-Mass Accuracy Mass Spectrometry. | Smith A, Iablokov V et al. | Kidney Blood Press Res 2020;45(2):233-248 | https://doi.org/10.1159/000505187 |
On-Tissue Derivatization Strategy for Mass Spectrometry Imaging of Carboxyl-Containing Metabolites in Biological Tissues. | Sun C, Liu W et al. | Anal Chem 2020;92(18):12126-12131 | https://doi.org/10.1021/acs.analchem.0c02303 |
Development of a high-coverage matrix-assisted laser desorption/ionization mass spectrometry imaging method for visualizing the spatial dynamics of functional metabolites in Salvia miltiorrhiza Bge. | Sun C, Liu W et al. | J Chromatogr A 2020;1614:460704 | https://doi.org/10.1016/j.chroma.2019.460704 |
1,1'-binaphthyl-2,2'-diamine as a novel MALDI matrix to enhance the in situ imaging of metabolic heterogeneity in lung cancer. | Sun C, Liu W et al. | Talanta 2020;209:120557 | https://doi.org/10.1016/j.talanta.2019.120557 |
The choice of tissue fixative is a key determinant for mass spectrometry imaging based tumor metabolic reprogramming characterization. | Sun C, Wang F et al. | Anal Bioanal Chem 2020;412(13):3123-3134 | https://doi.org/10.1007/s00216-020-02562-3 |
A spatially-resolved approach to visualize the distribution and biosynthesis of flavones in Scutellaria baicalensis Georgi. | Sun C, Zhang M et al. | J Pharm Biomed Anal 2020;179:113014 | https://doi.org/10.1016/j.jpba.2019.113014 |
Mass Spectrometry Imaging Establishes 2 Distinct Metabolic Phenotypes of Aldosterone-Producing Cell Clusters in Primary Aldosteronism. | Sun N, Meyer LS et al. | Hypertension 2020;75:634-644 | https://doi.org/10.1161/HYPERTENSIONAHA.119.14041 |
Effects of Thymoquinone on Small-Molecule Metabolites in a Rat Model of Cerebral Ischemia Reperfusion Injury Assessed using MALDI-MSI. | Tian F, Liu R et al. | Metabolites 2020;10(1) | https://doi.org/10.3390/metabo10010027 |
Considerations for MALDI-Based Quantitative Mass Spectrometry Imaging Studies. | Tobias F ,Hummon AB | J Proteome Res 2020;19(9):3620-3630 | https://doi.org/10.1021/acs.jproteome.0c00443 |
Sample Preparation for Metabolic Profiling using MALDI Mass Spectrometry Imaging. | Veerasammy K, Chen YX et al. | J Vis Exp 2020 | https://doi.org/10.3791/62008 |
Response Surface Methodology As a New Approach for Finding Optimal MALDI Matrix Spraying Parameters for Mass Spectrometry Imaging. | Veličković D, Zhang G et al. | J Am Soc Mass Spectrom 2020;31(3):508-516 | https://doi.org/10.1021/jasms.9b00074 |
Investigation of Xenobiotics Metabolism In Salix alba Leaves via Mass Spectrometry Imaging. | Villette C ,Maurer L ,Heintz D | J Vis Exp 2020 | https://doi.org/10.3791/61011 |
Localization of the lens intermediate filament switch by imaging mass spectrometry. | Wang Z ,Ryan DJ ,Schey KL | Exp Eye Res 2020;198:108134 | https://doi.org/10.1016/j.exer.2020.108134 |
Opisthobranch grazing results in mobilisation of spherulous cells and re-allocation of secondary metabolites in the sponge Aplysina aerophoba. | Wu YC, García-Altares M et al. | Sci Rep 2020;10(1):21934 | https://doi.org/10.1038/s41598-020-78667-7 |
Spatial Lipidomics Reveals Anticancer Mechanisms of Bufalin in Combination with Cinobufagin in Tumor-Bearing Mice. | Zhang J, Hong Y et al. | Front Pharmacol 2020;11:593815 | https://doi.org/10.3389/fphar.2020.593815 |
Evaluation of the splenic injury following exposure of mice to bisphenol S: A mass spectrometry-based lipidomics and imaging analysis. | Zhao C, Yong T et al. | Environ Int 2020;135:105378 | https://doi.org/10.1016/j.envint.2019.105378 |
Title | Author | Publication | Link |
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Extracellular Matrix Alterations in Low Grade Lung Adenocarcinoma Compared to Normal Lung Tissue by Imaging Mass Spectrometry | Angel PM, Bruner E et al. | Journal of Mass Spectrometry. 2019 | https://doi.org/10.1002/jms.4450 |
Extracellular Matrix Imaging of Breast Tissue Pathologies by MALDI–Imaging Mass Spectrometry | Angel PM, Schwamborn K et al. | PROTEOMICS–Clinical Applications. 2019;13(1):1700152 | https://doi.org/10.1002/prca.201700152 |
Neratinib protects pancreatic beta cells in diabetes | Ardestani A, Li S et al. | Nature communications. 2019;10(1):1-17 | https://doi.org/10.1038/s41467-019-12880-5 |
Integrative Clustering in Mass Spectrometry Imaging for Enhanced Patient Stratification | Balluff B, Buck A et al. | PROTEOMICS–Clinical Applications. 2019;13(1):1800137 | https://doi.org/10.1002/prca.201800137 |
Dual strategy for reduced signal-suppression effects in matrix-assisted laser desorption/ionization mass spectrometry imaging | Bastrup J, Birkelund S et al. | Rapid Communications in Mass Spectrometry. 2019;33(22):1711-21 | https://doi.org/10.1002/rcm.8521 |
Metal Oxide Laser Ionization Mass Spectrometry Imaging (MOLI MSI) Using Cerium (IV) Oxide | Basu SS, McMinn MH et al. | Analytical chemistry. 2019;91(10):6800-7 | https://doi.org/10.1021/acs.analchem.9b00894 |
Rapid MALDI mass spectrometry imaging for surgical pathology | Basu SS, Regan MS et al. | NPJ precision oncology. 2019;3(1):1-5 | https://doi.org/10.1038/s41698-019-0089-y |
MALDI Mass Spectrometry Imaging Linked with Top-Down Proteomics as a Tool to Study the Non-Small-Cell Lung Cancer Tumor Microenvironment | Berghmans E, Van Raemdonck G et al. | Methods and protocols. 2019;2(2):44 | https://doi.org/10.3390/mps2020044 |
Antibody Panel Based N-Glycan Imaging for N-Glycoprotein Biomarker Discovery | Black AP, Angel PM et al. | Current protocols in protein science. 2019;98(1):e99 | https://doi.org/10.1002/cpps.99 |
A novel mass spectrometry platform for multiplexed N-Glycoprotein biomarker discovery from patient biofluids by antibody panel based N-Glycan imaging | Black AP, Liang H et al. | Analytical chemistry. 2019;91(13):8429-35 | https://doi.org/10.1021/acs.analchem.9b01445 |
Using the chemical noise background in MALDI mass spectrometry imaging for mass alignment and calibration | Boskamp T, Lachmund D et al. | Analytical Chemistry. 2019 | https://doi.org/10.1021/acs.analchem.9b04473 |
Detection of small molecule concentration gradients in ocular tissues and humours | Boughton BA, Thomas OR et al. | Journal of Mass Spectrometry. 2019 | https://doi.org/10.1002/jms.4460 |
MALDI Mass Spectrometry Imaging of Early- and Late-Stage Serous Ovarian Cancer Tissue Reveals Stage-Specific N-Glycans | Briggs MT, Condina MR et al. | Proteomics. 2019;19(21-22):1800482 | https://doi.org/10.1002/pmic.201800482 |
Translating N-glycan analytical applications into clinical strategies for ovarian cancer | Briggs MT, Condina MR et al. | PROTEOMICS–Clinical Applications. 2019;13(3):1800099 | https://doi.org/10.1002/prca.201800099 |
Mass spectrometry-based integration and expansion of the chemical diversity harbored within a marine sponge | Cantrell TP, Freeman CJ et al. | Journal of The American Society for Mass Spectrometry. 2019;30(8):1373-84 | https://doi.org/10.1021/jasms.8b06062 |
Development of a class prediction model to discriminate pancreatic ductal adenocarcinoma from pancreatic neuroendocrine tumor by MALDI mass spectrometry imaging | Casadonte R, Kriegsmann M et al. | PROTEOMICS–Clinical Applications. 2019;13(1):1800046 | https://doi.org/10.1002/prca.201800046 |
Biofilm inhibitor taurolithocholic acid alters colony morphology, specialized metabolism, and virulence of Pseudomonas aeruginosa | Condren AR, Kahl LJ et al. | ACS Infectious Diseases. 2019 | https://doi.org/10.1021/acsinfecdis.9b00424 |
Targeted feature extraction in MALDI mass spectrometry imaging to discriminate proteomic profiles of breast and ovarian cancer | Cordero Hernandez Y, Boskamp T et al. | PROTEOMICS–Clinical Applications. 2019;13(1):1700168 | https://doi.org/10.1002/prca.201700168 |
Assessing the effect of nitisinone induced hypertyrosinaemia on monoamine neurotransmitters in brain tissue from a murine model of alkaptonuria using mass spectrometry imaging | Davison AS, Strittmatter N et al. | Metabolomics. 2019;15(5):68 | https://doi.org/10.1007/s11306-019-1531-4 |
Age-related spatial differences of human lens UV filters revealed by negative ion mode MALDI imaging mass spectrometry | Demarais NJ, Donaldson PJ, Grey AC | Experimental eye research. 2019;184:146-51 | https://doi.org/10.1016/j.exer.2019.04.016 |
Defining the Human Kidney N-Glycome in Normal and Cancer Tissues Using MALDI Imaging Mass Spectrometry | Drake RR, McDowell C et al. | Journal of Mass Spectrometry. 2019:e4490 | https://doi.org/10.1002/jms.4490 |
Spatially resolved endogenous improved metabolite detection in human osteoarthritis cartilage by matrix assisted laser desorption ionization mass spectrometry imaging | Eveque-Mourroux M, Emans P et al. | Analyst. 2019;144(20):5953-8 | https://doi.org/10.1039/C9AN00944B |
Pre-and Postoperative Neratinib for HER2-Positive Breast Cancer Brain Metastases: Translational Breast Cancer Research Consortium 022 | Freedman RA, Gelman RS et al. | Clinical breast cancer. 2019 | https://doi.org/10.1016/j.clbc.2019.07.011 |
Spatial UBE2N protein expression indicates genomic instability in colorectal cancers | Gemoll T, Miroll E et al. | BMC cancer. 2019;19(1):710 | https://doi.org/10.1186/s12885-019-5856-1 |
MALDI-Mass Spectrometry Imaging to Investigate Lipid and Bile Acid Modifications Caused by Lentil Extract Used as a Potential Hypocholesterolemic Treatment | Genangeli M, Heijens AM et al. | Journal of the American Society for Mass Spectrometry. 2019;30(10):2041-50 | https://doi.org/10.1021/jasms.8b06217 |
Spatio-Temporal Metabolite and Elemental Profiling of Salt Stressed Barley Seeds During Initial Stages of Germination by MALDI-MSI and μ-XRF Spectrometry | Gupta SVK, Rupasinghe TWT et al. | Frontiers in plant science. 2019;10:1139 | https://doi.org/10.3389/fpls.2019.01139 |
Revealing the Regional Localization and Differential Lung Retention of Inhaled Compounds by Mass Spectrometry Imaging | Hamm GR, Bäckström E et al. | Journal of aerosol medicine and pulmonary drug delivery. 2019 | https://doi.org/10.1089/jamp.2019.1536 |
Polydopamine-capped AgNPs as a novel matrix overcoming the ion suppression of phosphatidylcholine for MALDI MS comprehensive imaging of glycerophospholipids and sphingolipids in impact-induced injured brain | Han C, Li S et al. | Analyst. 2019;144(21):6304-12 | https://doi.org/10.1039/C9AN01361J |
MALDI Imaging Mass Spectrometry: Neurochemical Imaging of Proteins and Peptides | Hanrieder J, Zetterberg H, Blennow K. | Neuroproteomics: Springer; 2019. p. 179-97 | https://doi.org/10.1007/978-1-4939-9662-9_15 |
Identification of Proteomic Markers in Head and Neck Cancer Using MALDI–MS Imaging, LC–MS/MS, and Immunohistochemistry | Hoffmann F, Umbreit C et al. | PROTEOMICS – Clinical Applications. 2019;13(1):1700173. doi: 10.1002/prca.201700173 | https://doi.org/10.1002/prca.201700173 |
Matrix-assisted laser desorption/ionization mass spectrometry imaging to uncover protein alterations associated with the progression of IgA nephropathy | Ivanova M, Dyadyk O et al. | Virchows Archiv. 2019:1-12 | https://doi.org/10.1007/s00428-019-02705-7 |
Sample Preparation Strategies for High-Throughput Mass Spectrometry Imaging of Primary Tumor Organoids | Johnson J, Sharick JT et al. | Journal of Mass Spectrometry. 2019 | https://doi.org/10.1002/jms.4452 |
MALDI-Imaging for Classification of Epithelial Ovarian Cancer Histotypes from a Tissue Microarray Using Machine Learning Methods | Klein O, Kanter F et al. | PROTEOMICS–Clinical Applications. 2019;13(1):1700181 | https://doi.org/10.1002/prca.201700181 |
The Emerging Role of Cytoskeletal Proteins as Reliable Biomarkers | Klingler-Hoffmann M, Mittal P, Hoffmann P | Proteomics. 2019;19(21-22):1800483 | https://doi.org/10.1002/pmic.201800483 |
Mapping natural dyes in archeological textiles by imaging mass spectrometry | Kramell AE, García-Altares M et al. | Scientific reports. 2019;9(1):1-9 | https://doi.org/10.1038/s41598-019-38706-4 |
MALDI imaging for proteomic painting of heterogeneous tissue structures | Kriegsmann J, Kriegsmann M et al. | PROTEOMICS–Clinical Applications. 2019;13(1):1800045 | https://doi.org/10.1002/prca.201800045 |
Combined Immunohistochemistry after Mass Spectrometry Imaging for superior spatial information | Kriegsmann K, Longuespée R et al. | PROTEOMICS–Clinical Applications. 2019;13(1):1800035 | https://doi.org/10.1002/prca.201800035 |
Derangements of amino acids in cachectic skeletal muscle are caused by mitochondrial dysfunction | Kunzke T, Buck A et al. | Journal of Cachexia, Sarcopenia and Muscle. 2019 | https://doi.org/10.1002/jcsm.12498 |
MALDI imaging in Fabry nephropathy: a multicenter study | L’Imperio V, Smith A et al. | Journal of nephrology. 2019:1-8 | https://doi.org/10.1007/s40620-019-00627-w |
Histopathology-guided mass spectrometry differentiates benign nevi from malignant melanoma | Lazova R, Smoot K et al. | Journal of cutaneous pathology. 2019 | https://doi.org/10.1111/cup.13610 |
MALDI–MSI Pilot Study Highlights Glomerular Deposits of Macrophage Migration Inhibitory Factor as a Possible Indicator of Response to Therapy in Membranous Nephropathy | L’Imperio V, Smith A et al. | PROTEOMICS–Clinical Applications. 2019;13(3):1800019 | https://doi.org/10.1002/prca.201800019 |
Metabolomics profiling of methamphetamine addicted human serum and three rat brain areas | Lin M, Xu J et al. | RSC Advances. 2019;9(70):41107-19 | https://doi.org/10.1039/C9RA08096A |
Effect of Shenfu injection on lipopolysaccharide (LPS)-induced septic shock in rabbits | Liu X, Liu R et al. | Journal of ethnopharmacology. 2019;234:36-43 | https://doi.org/10.1016/j.jep.2019.01.008 |
In MALDI–Mass Spectrometry Imaging on Formalin-Fixed Paraffin-Embedded Tissue Specimen Section Thickness Significantly Influences m/z Peak Intensity | Longuespée R, Kriegsmann K et al. | PROTEOMICS–Clinical Applications. 2019;13(1):1800074 | https://doi.org/10.1002/prca.201800074 |
Site-to-Site Reproducibility and Spatial Resolution in MALDI–MSI of Peptides from Formalin-Fixed Paraffin-Embedded Samples | Ly A, Longuespée R et al. | PROTEOMICS–Clinical Applications. 2019;13(1):1800029 | https://doi.org/10.1002/prca.201800180 |
Enhanced Coverage of Insect Neuropeptides in Tissue Sections by an Optimized Mass-Spectrometry-Imaging Protocol | Ly A, Ragionieri L et al. | Analytical chemistry. 2019;91(3):1980-8 | https://doi.org/10.1021/acs.analchem.8b04304 |
Maldi msi of lipids in experimental model of traumatic brain injury detects acylcarnitines as injury related markers | lah K, Quanico J et al. | 2019 | https://doi.org/10.1021/acs.analchem.9b02633 |
Distinguishing core from penumbra by lipid profiles using Mass Spectrometry Imaging in a transgenic mouse model of ischemic stroke | Mulder I, Potočnik NO et al. | Scientific reports. 2019;9(1):1-10 | https://doi.org/10.1038/s41598-018-37612-5 |
Intratumoral immunotherapy with TLR7/8 agonist MEDI9197 modulates the tumor microenvironment leading to enhanced activity when combined with other immunotherapies | Mullins SR, Vasilakos JP et al. | Journal for immunotherapy of cancer. 2019;7(1):1-18 | https://doi.org/10.1186/s40425-019-0724-8 |
Evaluation of Small Molecule Drug Uptake in patient-Derived prostate cancer explants by Mass Spectrometry | Mutuku SM, Trim PJ et al. | Scientific reports. 2019;9(1):1-11 | https://doi.org/10.1038/s41598-019-51549-3 |
Keeping the shape of plant tissue for visualizing metabolite features in segmentation and correlation analysis of imaging mass spectrometry in Asparagus officinalis | Nakabayashi R, Hashimoto K et al. | Metabolomics. 2019;15(2):24 | https://doi.org/10.1007/s11306-019-1486-5 |
Unsupervised machine learning using an imaging mass spectrometry dataset automatically reassembles grey and white matter | Nampei M, Horikawa M et al. | Scientific reports. 2019;9(1):1-11 | https://doi.org/10.1038/s41598-019-49819-1 |
MALDI-imaging mass spectrometry screening of lipid profile changes in the rat model for tauopathies | Olesova D, Majerova P, Kovac A | 4th Meeting of Middle European Societies for Immunology and Allergology; 2019: Wiley Online Library | https://doi.org/10.1002/eji.201970500 |
Higher mass accuracy MALDI-TOF/TOF lipid imaging of human brain tissue in Alzheimer’s disease | O’Rourke MB, Smith CC et al. | Current protocols in molecular biology. 2019;126(1):e86 | https://doi.org/10.1002/cpmb.86 |
‘What did I do wrong?’ An empirical evaluation of sample preparation methodologies in matrix-assisted laser desorption/ionization-mass spectrometry imaging | O’Rourke MB, Smith CC et al. | Future Science OA. 2019;5(4):FSO362 | https://doi.org/10.4155/fsoa-2018-0095 |
Three-dimensional mass spectrometry imaging identifies lipid markers of medulloblastoma metastasis | Paine MR, Liu J et al. | Scientific reports. 2019;9(1):1-10 | https://doi.org/10.1038/s41598-018-38257-0 |
Lipidomic changes in the rat hippocampus following cocaine conditioning, extinction, and reinstatement of drug-seeking | Pati S, Angel P et al. | Brain and behavior. 2019;9(12):e01451 | https://doi.org/10.1002/brb3.1451 |
Uncovering Matrix Effects on Lipid Analyses in MALDI Imaging Mass Spectrometry Experiments | Perry WJ, Patterson NH et al. | Journal of Mass Spectrometry. 2019:e4491 | https://doi.org/10.1002/jms.4491 |
Novel prognostic markers in triple-negative breast cancer discovered by MALDI-mass spectrometry imaging | Phillips L, Gill AJ, Baxter RC | Frontiers in oncology. 2019;9:379 | https://doi.org/10.3389/fonc.2019.00379 |
Molecular characterization of prostate cancer with associated Gleason score using mass spectrometry imaging | Randall EC, Zadra G et al. | Molecular Cancer Research. 2019;17(5):1155-65 | https://doi.org/10.1158/1541-7786.MCR-18-1057 |
Mapping insoluble indole metabolites in the gastrointestinal environment of a murine colorectal cancer model using desorption/ionisation on porous silicon imaging | Rudd DA, Benkendorff K et al. | Scientific reports. 2019;9(1):1-13 | https://doi.org/10.1038/s41598-019-48533-2 |
Comparative spatial lipidomics analysis reveals cellular lipid remodelling in different developmental zones of barley roots in response to salinity | Sarabia LD, Boughton BA et al. | Plant, cell & environment. 2019 | https://doi.org/10.1111/pce.13653 |
In plaque-mass spectrometry imaging of a bloom-forming alga during viral infection reveals a metabolic shift towards odd-chain fatty acid lipids | Schleyer G, Shahaf N et al. | Nature microbiology. 2019;4(3):527-38 | https://doi.org/10.1038/s41564-018-0336-y |
Maintenance of Deep Lung Architecture and Automated Airway Segmentation for 3D Mass Spectrometry Imaging | Scott AJ, Chandler CE et al. | Scientific Reports. 2019;9(1):1-12 | https://doi.org/10.1038/s41598-019-56364-4 |
Microscopy and Mass Spectrometry Imaging Reveals the Distributions of Curcumin Species in Dried Turmeric Root | Shimma S, Sagawa T | Journal of Agricultural and Food Chemistry. 2019;67(34):9652-7. doi: 10.1021/acs.jafc.9b02768 | https://doi.org/10.1021/acs.jafc.9b02768 |
Molecular signatures of medullary thyroid carcinoma by matrix-assisted laser desorption/ionisation mass spectrometry imaging | Smith A, Galli M et al. | Journal of proteomics. 2019;191:114-23 | https://doi.org/10.1016/j.jprot.2018.03.021 |
High Spatial Resolution MALDI-MS Imaging in the Study of Membranous Nephropathy | Smith A, L’Imperio V et al. | PROTEOMICS–Clinical Applications. 2019;13(1):1800016 | https://doi.org/10.1002/prca.201800016 |
High-Performance Molecular Imaging with MALDI Trapped Ion-Mobility Time-of-Flight (timsTOF) Mass Spectrometry | Spraggins JM, Djambazova KV et al. | Analytical chemistry. 2019;91(22):14552-60 | https://doi.org/10.1021/acs.analchem.9b03612 |
Ambient metabolic profiling and imaging of biological samples with ultrahigh molecular resolution using laser ablation electrospray ionization 21 tesla FTICR mass spectrometry | Stopka SA, Samarah LZ et al. | Analytical chemistry. 2019;91(8):5028-35 | https://doi.org/10.1021/acs.analchem.8b05084 |
Sarcosine is a prostate epigenetic modifier that elicits aberrant methylation patterns through the SAM e-Dnmts axis | Strmiska V, Michalek P et al. | Molecular oncology. 2019;13(5):1002-17 | https://doi.org/10.1002/1878-0261.12439 |
The use of 1, 5-diaminonaphthalene for matrix-assisted laser desorption/ionization mass spectrometry imaging of brain in neurodegenerative disorders | Strnad Š, Pražienková V et al. | Talanta. 2019;201:364-72 | https://doi.org/10.1016/j.talanta.2019.03.117 |
Acetone immersion enhanced MALDI-MS imaging of small molecule metabolites in biological tissues | Sun C, Li Z et al. | Journal of pharmaceutical and biomedical analysis. 2019;176:112797 | https://doi.org/10.1016/j.jpba.2019.112797 |
A process of convergent amplification and tissue-specific expression dominates the evolution of toxin and toxin-like genes in sea anemones | Surm JM, Smith HL et al. | Molecular ecology. 2019;28(9):2272-89 | https://doi.org/10.1111/mec.15084 |
Quantitative MALDI imaging of spatial distributions and dynamic changes of tetrandrine in multiple organs of rats | Tang W, Chen J et al. | Theranostics. 2019;9(4):932 | https://dx.doi.org/10.7150%2Fthno.30408 |
Deciphering PSE-like muscle defect in cooked hams: A signature from the tissue to the molecular scale | Théron L, Sayd T et al. | Food chemistry. 2019;270:359-66 | https://doi.org/10.1016/j.foodchem.2018.07.081 |
Developing a Drug Screening Platform: MALDI-Mass Spectrometry Imaging of Paper-Based Cultures | Tobias F, McIntosh JC et al. | Analytical chemistry. 2019;91(24):15370-6 | https://doi.org/10.1021/acs.analchem.9b03536 |
Peptide Profile Differences of Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features, Encapsulated Follicular Variant, and Classical Papillary Thyroid Carcinoma: An Application of Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging | Ucal Y, Tokat F et al. | Thyroid. 2019;29(8):1125-37 | https://doi.org/10.1089/thy.2018.0392 |
Molecular imaging identifies age-related attenuation of acetylcholine in retrosplenial cortex in response to acetylcholinesterase inhibition | Vallianatou T, Shariatgorji M et al. | Neuropsychopharmacology. 2019;44(12):2091-8 | https://doi.org/10.1038/s41386-019-0397-5 |
Rapid Identification of Ischemic Injury in Renal Tissue by Mass-Spectrometry Imaging | van Smaalen T, Ellis S et al. | Analytical chemistry. 2019;91(5):3575-81 | https://doi.org/10.1021/acs.analchem.8b05521 |
Mass spectrometric imaging of cysteine rich proteins in human skin | Vanickova L, Guran R et al. | International journal of biological macromolecules. 2019;125:270-7 | https://doi.org/10.1016/j.ijbiomac.2018.11.272 |
An approach for visualizing the spatial metabolome of an entire plant root system inspired by the Swiss-rolling technique | Veličković D, Chu RK et al. | Journal of Mass Spectrometry. 2019 | https://doi.org/10.1002/jms.4363 |
Spatiotemporal Transformation in the Alkaloid Profile of Pinus Roots in Response to Mycorrhization | Veličković D, Liao H-L et al. | Journal of natural products. 2019;82(5):1382-6 | https://doi.org/10.1021/acs.jnatprod.8b01050 |
In situ localization of micropollutants and associated stress response in Populus nigra leaves | Villette C, Maurer L et al. | Environment international. 2019;126:523-32 | https://doi.org/10.1016/j.envint.2019.02.066 |
Strategies for managing multi-patient 3D mass spectrometry imaging data | Vos D, Jansen I et al. | Journal of proteomics. 2019;193:184-91 | https://doi.org/10.1016/j.jprot.2018.10.008 |
Software solutions for evaluation and visualization of laser ablation inductively coupled plasma mass spectrometry imaging (LA-ICP-MSI) data: a short overview | Weiskirchen R, Weiskirchen S et al. | Journal of cheminformatics. 2019;11(1):16 | https://doi.org/10.1186/s13321-019-0338-7 |
Pharmacodynamic Evaluation of Shenfu Injection in Rats With Ischemic Heart Failure and Its Effect on Small Molecules Using Matrix-Assisted Laser Desorption/Ionization–Mass Spectrometry Imaging | Wu H, Dai Z et al. | Frontiers in Pharmacology. 2019;10(1424). doi: 10.3389/fphar.2019.01424 | https://doi.org/10.3389/fphar.2019.01424 |
For Research Use Only. Not for use in clinical diagnostic procedures.