Comparative assessment of mAb higher order structure in biopharmaceutical development using novel NMR and chemometric analysis
Webinar Overview
Developments in pulse sequences and instrumentation along with the incorporation of chemometric tools permit NMR spectroscopy to report comparative metrics for higher order structure analysis (HOS) of intact monoclonal antibodies (mAbs). These 1D and 2D NMR chemometric methods can be used in different applications, including forced degradation HOS studies on mAbs, given the high sensitivity and resolution of the technique.
This presentation was part of the Well Characterized Biologics 2021 Conference program.
October 26, 2021
Key Learning Topics
- Importance of biologics and NMR in the pharmaceutical industry
- Chemometric tools in NMR HOS comparability
- Case Study: FD study of adalimumab and trastuzumab
Who should attend
The webinar is aimed for those working in the pharmaceutical industry, especially in drug development and production of pharmaceuticals and biopharmaceuticals. Laboratory managers, heads of R&D, analytical development, quality control and manufacturing.
Additionally, the webinar is also of interest to those academics collaborating with pharmaceutical industry and to other industries who face challenges in formulating both solid and liquid mixtures.