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Microbiology & Diagnostics

Microbial Identification

Unbiased and fast identification of microorganisms down to the species level

Identification of microorganisms

Significant advances in microbiology have been achieved thanks to continuous innovations in mass spectrometry (MS) over the past decade. Now the standard in microorganism identification, Matrix-Assisted Laser Desorption/Ionization Time-Of-Flight (MALDI-TOF) MS enables microbiology laboratories to reliably and rapidly identify microbes, in a cost-effective manner.

A revolution in microbiology

Microorganisms identification to the species level is a key task of microbiology. Traditionally has been achieved by carrying out labour-intensive and time-consuming biochemical assays. Though current sequencing technologies may provide very precise insights, they are still far too slow and expensive. Bruker has successfully introduced an innovative, molecular-based mass spectrometric identification method that enables faster and more efficient analysis than conventional assays or sequencing.

By using our experience and expertise as a worldwide leading provider of MALDI-TOF mass spectrometry, Bruker developed the MALDI Biotyper® - a revolutionary approach for the analysis of microorganisms. This "Open Microbiology Concept" includes interfacing, own library creation and can be easily integrated into any laboratory environment. Within just a few years, the MALDI Biotyper® has become the worldwide leading solution for clinical microbiology, as well as for water, pharmaceutical and food testing.

MALDI Biotyper® - Changing microbiology

The MALDI Biotyper® (MBT) is a microbial identification system based on MALDI-TOF mass spectrometry, allowing unbiased identification of microorganisms within a few minutes down to the species level. The MBT is an easy, rapid, robust, high-throughput, cost-effective and efficient identification technology, ideally suited to microbial laboratories.

Due to its broad applicability, speed of analysis and low sample processing costs, the MBT is ideally suited to the role of microorganism identification. MALDI-TOF MS determines the unique proteomic fingerprint of an organism, and matches characteristic patterns with an extensive reference library to determine the organism´s identity. Continuous expansion of the reference library ensures that a broad range of microorganisms can be identified easily.

Bruker´s state-of-the art MALDI Biotyper® solutions

The best technology from the experts in mass spectrometry. As the leader in MALDI-TOF technology it is of great importance to Bruker to design robust, compact high-performance platforms intended for extensive and routine use in the microbiology laboratory.
The MALDI Biotyper® is a modular system designed to be configured according to individual laboratory needs. Bruker offers laboratories the choice of the microbial MALDI-TOF mass spectrometer that best fits their needs. Continuous hardware development has led to the 4th generation of Bruker´s benchtop MALDI Biotyper® system.

  • The NEW MALDI Biotyper® sirius one GP or RUO System, with Bruker´s proprietary lifetime* smartbeam™ solid state laser technology at 200 Hz repetition rate and positive ion mode. System improvements, including the newest electronics and high-performance vacuum system, generate very fast target exchange.
  • The NEW MALDI Biotyper® sirius GP or RUO System, with the same improvements, smartbeam™ 200 Hz laser and positive as well as negative ion detection. The additional capability of analysis in negative ion mode broadens the research applications, such as the analysis of lipids.
* Lifetime meaning 7 years or 500 million shots, whichever comes first.

 

For General Purpose use [In the United States, Japan and Taiwan: For Research Use Only (RUO)].

Not for use in clinical diagnostic procedures. Please contact your local representative for availability in your country.

MALDI Biotyper® sirius one System (GP + RUO)

The new MALDI Biotyper® sirius one RUO System / MALDI Biotyper® sirius one GP System is the latest instrument in the market leading MALDI Biotyper product portfolio for rapid and accurate microorganism identification.

MALDI Biotyper® sirius System (GP + RUO)

The new MALDI Biotyper® sirius System (GP + RUO) has been launched in the scope of broadening research capabilities, including resistance detection applications based on the analysis of lipids in the negative ion mode. Microbial identification is performed using positive ion mode only.

MALDI Biotyper® Library RUO

The principle behind identification of microorganisms with the MALDI Biotyper® (MBT) is the comparison of the mass spectrum of an unknown organism with a library of reference mass spectra.

Pharmaceutical Microbiology

Pharmaceutical microbiologists are responsible for ensuring that the supply of life-saving drugs and vaccines are free from microorganism contamination. By maintaining product safety and quality with reliable microbial testing, the downtime of production and delay in deliveries can be minimized, while ensuring regulatory compliance. Pharmaceutical companies require microbial identification not only for production line control, but also for sterile products such as vaccines.

Veterinary Microbiology

Among the current critical challenges facing veterinary microbiologists is the need to obtain secure species identification of rare and challenging organisms affecting animals, in a timely manner.

Water Testing Microbiology

Accurate identification of waterborne pathogens and quality indicators is key in microbial water testing.

Food & Beverage Microbiology

Accurate microbiological testing technology is vital for the detection of foodborne pathogens, possible food spoilage organisms and technological strains. Rapid identification and confirmation methods enable food and beverage manufacturers to make fast quality and safety decisions.

Microbiological Research

Identify and classify microorganisms for microbiological research and resistance testing

Microbial Strain Typing

Fast, easy and cost-effective strain typing for effective hospital hygiene management and microbial quality control in food and beverage production.