NMR Software


Bruker has created CMC-assist for assisted NMR data interpretation and workflow streamlining. Its main application is synthesis control

CMC-assist is Bruker’s NMR software for assisted NMR data interpretation and workflow streamlining.


We would like to inform you, that from April 1st, 2022 CMC-assist will no longer be available for purchase. Our support for CMC-assist users will continue until March 31st, 2025.

Assisted NMR Data Interpretation and Workflow Streamlining

Designed for NMR end-users, CMC-assist efficiently extracts information from complex NMR data, conducts consistency and concentration assessments and generates detailed reports for direct transfer to publications, patents and lab journals.

The main application of CMC-assist is synthesis control of small organic molecules.

CMC-assist not only excels as an off-line analysis interface but its automated NMR interpretation power can also be used to generate results directly at any Bruker NMR instrument equipped with the latest control software, making it the most efficient and streamlined NMR workflow on the market.

For teaching purposes, CMC-assist is also available as a Classroom edition, which includes all the chemistry centered NMR features of CMC-assist, except the automatic spectra assignment. In addition, extensive supporting materials and training data sets is available.

The Classroom edition is available only for academia, since March 1st 2019 is the CMC-se Classroom license integral part of Topspin for academia.


Different reports can be generated at the click of a button.

  • Detailed format with consistency information, concentration, assignment table, overview spectrum, detailed expansions and string descriptions in various formats
  • Short format with assignment table, concentration and consistency statement
  • Patent and publication string providing direct transfer to any other application in various journal formats (including Journal of Organic Chemistry (JOC); Journal of Medicinal Chemistry; Journal of the American Chemical Society (JACS); Angewandte Chemie; Chemistry, a European Journal; Helvetica Chimica Acta; Tetrahedron Letters; Journal of Natural Products; Analytical Chemistry; Planta Medica; Organic Letters; Phytochemistry; Fitoterapia; Bioorganic and Medicinal Chemistry Letters)
  • CMC-assist supports the NMReData format

Technical Details

Data Processing

CMC-assist enables all 1D and 2D NMR processing steps such as fourier transformation or phase- and baseline correction. These steps can be performed automatically or manually.

Automatic Spectra Interpretation

CMC-assist features the most innovative, high performance system for automatic spectra interpretation including automatic structure verification (ASV), concentration determination, spectrum assignment as well as integral and multiplet interpretation.

Manual Analysis Refinement

The intuitive graphical user interface enables quick manual refinement of automated analytical results.


Service & Life Cycle Support for Magnetic Resonance and Preclinical Imaging

Bruker’s commitment to provide customers with unparalleled help throughout the buying cycle, from initial inquiry to evaluation, installation, and the lifetime of the instrument is now characterized by the LabScape service concept.

LabScape Maintenance Agreements, On-Site On-Demand and Enhance Your Lab are designed to offer a new approach to maintenance and service for the modern laboratory