Introduction to NMR applications used in pharmaceutical industry for QC, screening and mixture analysis.
In lectures and practical sessions the concepts of 1D and 2D NMR experiments like waterLOGSY, Saturation Transfer Difference and relaxation based methods to probe for binding of small-molecules to biomolecular targets are elaborated. The participants will learn practical aspects of data analysis in small groups. Further topics are the use of CMCa and ASSURE for quality control of fragment libraries and mixture analysis. In most cases, the above applications are run in high-throughput with appropriate automation routines and robotics which will be introduced to the participants during hands-on sessions. Lectures about the theory of fragment binding to biomolecular targets in the context of the NMR time scale complete the program.
The broad scope of the training course makes it a perfect introduction for scientist from academia and industry with a background in chemistry, biology or biochemistry with interest in using NMR for the above applications.
Open to all AVANCE spectrometer users from academia and industry interested in the above topics
September 6th-8th, 2017
€ 1200 plus VAT
(incl. documentation, coffee breaks and lunch)
Mrs. Svetlana Startseva
Bruker BioSpin AG