Bruker Center of Excellence in Proteomics
UCSF San Francisco, CA
Unveiling the Future of Proteomics: Bruker Center of Excellence Grand Opening
QBI presents for the exciting grand opening of the Bruker Center of Excellence in Proteomics, a cutting-edge Mass Spectrometry Facility housed within the UCSF Joan & Sanford I. Weill Neurosciences Building.
This is your chance to:
- Be among the first to explore this state-of-the-art facility
- Gain insights into the latest advancements in single-cell proteomics
- Network with leading researchers in the field
- Enjoy a complimentary lunch discussion with renowned experts
Featured speakers
Ryan Kelly, Professor, Department of Chemistry and Biochemistry, Brigham Young University, Provo, UT, USA
Chris Rose, Ph.D., Distinguished Scientist and Senior Director, Discovery Proteomics, Genentech, San Francisco, CA, USA
Danielle Swaney, Ph.D., Assistant Professor, Cellular Molecular Pharmacology, University of California, San Francisco, CA, USA
Agenda
11:00 - 12:00 am - Registration and Check-In
12:00 - 12:15 pm - Grand Opening Ceremony - Ribbon Cutting
12:15 - 12:45 pm - Single-Cell Proteomics: Recent Developments and Near-Term Prospects
Abstract: Biological tissues are highly heterogeneous, consisting of a variety of cell types, states and subpopulations, and understanding heterogeneity at the single cell level is of great interest for biomedical research. We have developed strategies to minimize sample losses normally incurred during sample processing. In combination ultra-low-flow separations and latest-generation mass spectrometry instrumentation, we now achieve in-depth proteome coverage for low-input samples including single cells. To date, we can quantify >3000 proteins from single mammalian cells and achieve similar coverage for frozen and FFPE tissue squares as small as 50 µm. I will describe advances in cell isolation, sample preparation, ultrasensitive separations, MS acquisition and data analysis that have made this possible, as well as efforts to minimize or eliminate the need for custom instrumentation for such analyses. Finally, prospects for further dramatically improving the measurement throughput, depth of proteome coverage and quantitative accuracy for single-cell and other low-input proteomics studies will be discussed.
Speaker: Ryan Kelly
Discussion led by Danielle Swaney and Chris Rose
12:45 pm - Q&A Session
Don't miss this exciting opportunity to participate in the future of proteomics research. Space is limited. Secure your spot now!
Registration is closed
For Research Use Only. Not for use in clinical diagnostic procedures.